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Unit A Reproduction

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Figure 7 The zygote has divided several<br />

times. This ball of cells contains stem<br />

cells, which are unspecialized. As these<br />

cells divide, they can differentiate into all<br />

the different types of cells in the body.<br />

Figure 8 About one in 250 births<br />

produce identical twins.<br />

300X<br />

If you would like to learn more<br />

about stem cells, go to<br />

www.science.nelson.com GO<br />

Stem Cells and Differentiation<br />

The one-celled zygote has the instructions in its DNA to produce the more<br />

than 200 specialized types of cells in your body. Differentiation is the<br />

process of growing from unspecialized cells into many different specialized<br />

cells. After the zygote divides several times, it is a ball of roughly 150<br />

unspecialized cells (Figure 7). This ball has stem cells in it. Stem cells are<br />

unspecialized cells that have the ability to reproduce themselves. When stem<br />

cells undergo cell division, the daughter cells will either remain stem cells or<br />

begin differentiating into one of many different types of specialized cells.<br />

As the embryo grows and develops into a fetus, and these stem cells divide,<br />

they lose their ability to grow into all the different types of cells. These can<br />

then only differentiate into certain families of tissues. As the fetus develops<br />

further, stem cells are found in only certain tissues. Stem cells in these tissues<br />

can only form into the types of cells found in these tissues. For example, the<br />

stem cells found in the bone marrow can differentiate into the more than a<br />

dozen types of blood cells.<br />

Stem cells are of great interest to scientists because of their ability to<br />

differentiate into different types of cells. Scientists might be able to use this<br />

property of stem cells to develop new technologies. For example, scientists<br />

might be able to grow new heart muscle cells to replace cells that have been<br />

damaged in heart attacks. In order to do research, however, scientists need a<br />

source of stem cells. Stem cells can be found in certain adult tissues, such as<br />

bone marrow, and in the blood in the umbilical cord of a newborn. Another<br />

possible source is the extra embryos produced after in vitro fertilization (You<br />

will learn about in vitro fertilization in humans in Section 4.7.) Many eggs<br />

are fertilized, but only a few embryos are implanted. The extra embryos are<br />

frozen for future use. There is much controversy around stem cell research,<br />

and legislation in Canada controls the use of extra embryos for research. GO<br />

Twins<br />

Occasionally, more than one fetus develops inside the uterus. There are two<br />

types of twins: identical twins and fraternal twins. Fraternal twins occur<br />

when two eggs are released at the same time, usually one from each ovary.<br />

Since there are plenty of sperm cells in the oviducts, both eggs are fertilized.<br />

Each zygote develops its own placenta. Fraternal twins have the same<br />

birth date, but they are as similar or different as any brothers and sisters.<br />

They have different genetic material.<br />

Identical twins (Figure 8) result from one fertilized egg that splits at the<br />

zygote or early embryo stage. Normally, the zygote undergoes mitosis to<br />

become a ball of cells, which stay together and become an embryo.<br />

Occasionally, when the zygote undergoes cell division, the daughter cells<br />

separate from each other and each daughter cell develops into an embryo.<br />

However, they share the same placenta. These twins contain identical<br />

genetic material because they came from the same egg and sperm.<br />

Identical twins are the same gender because they contain identical DNA.<br />

120 <strong>Unit</strong> A <strong>Reproduction</strong><br />

NEL

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