Biology - HOT Science Lab
Biology - HOT Science Lab
Biology - HOT Science Lab
You also want an ePaper? Increase the reach of your titles
YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.
Student<br />
6. Prepare six individual nucleotides: use toothpicks to connect one black to one red<br />
Licorice piece. Then add one color candy piece perpendicularly to the black candy. Is this<br />
a full DNA strand Explain why or why not. ________________________________<br />
7. Assemble nucleotides into a polynucleotide strand by connecting the red piece of one<br />
nucleotide to the black of another. Continue until a strand of six nucleotides has been<br />
constructed. DRAW THIS IN YOUR JOURNAL.<br />
8. Which combinations of two bases form the complimentary base pair ―rungs‖ of DNA<br />
____________________________________________________________<br />
9. Assemble a strand that is complementary to the strand that you have already built. Place<br />
the second strand next to the first so that the complimentary "bases" touch. DRAW THIS<br />
STRUCTURE IN YOUR JOURNAL.<br />
10. Have your teacher check your model and initial your journal.<br />
11. You are now ready to REPLICATE!!!!<br />
12. To demonstrate replication, first make 12 more nucleotides with the same nitrogen bases<br />
as the first two strands.<br />
13. "Unzip" the DNA double strand, one ―rung‖ at a time.<br />
14. Assemble the proper nucleotides, one by one. DRAW THIS NEW STRUCTURE ALONG<br />
WITH THE ―OLD‖ ONE<br />
15. Once you have finished replicating, have your teacher check your model and initial your<br />
journal ________________________.<br />
16. After you demonstrate this to the teacher you may dispose of your models. This is one<br />
case where you may eat your science project, if you have kept everything clean. Be sure<br />
to remove toothpicks before you eat!!!<br />
17. Clean up, being sure that no toothpicks or sticky residue is left behind. Wash your hands!<br />
Observations/Data: Draw and describe the Nucleotides (step 7), the DNA strand (step 9), and<br />
the unzipped DNA strand (steps 12-14).<br />
Data Analysis/Conclusions:<br />
1. What is the function of DNA<br />
2. Why is it so important that the order of base pairs stays the same<br />
3. What would happen if there was a change in the base pair sequence<br />
4. What special proteins make replication of DNA possible<br />
5. What is the difference between replication and duplication<br />
6. At which stage of cell division (mitosis) does replication take place<br />
<strong>Biology</strong> HSL Page 206<br />
Curriculum and Instruction
Change language