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Night noise guidelines for Europe - WHO/Europe - World Health ...

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70<br />

EFFECTS ON HEALTH<br />

Regarding aircraft <strong>noise</strong>, the cross-sectional Okinawa study (Matsui et al., 2001;<br />

Matsui et al., 2004) on the association between aircraft <strong>noise</strong> and hypertension<br />

fulfils the inclusion criteria. When studies are included that did not assess<br />

dose–response relationships but only compared dichotomous categories of exposure<br />

in the analyses, two more studies appear on the list. The studies were carried<br />

out in the vicinity of Amsterdam Schiphol Airport. They suggest a higher risk of<br />

cardiovascular diseases in general (Knipschild, 1977b), and – specifically – <strong>for</strong><br />

hypertension and IHD (angina pectoris, ECG abnormalities, heart trouble)<br />

(Knipschild, 1977a) in subjects from areas exposed to high aircraft <strong>noise</strong>. These<br />

studies were considered in the meta-analysis by van Kempen et al. (2002).<br />

However, they do not fulfil the strict criteria set here. Finally, if the inclusion criteria<br />

are widened to include peer-reviewed studies that assessed dose–response<br />

relationships between objective indicators of exposure and the subjective (selfreported)<br />

prevalence of diseases, a further two studies can be considered. These<br />

are the cross-sectional study carried out in Stockholm regarding the association<br />

between aircraft <strong>noise</strong> and hypertension (Rosenlund et al., 2001), and the crosssectional<br />

part of the study in Berlin regarding the association between road traffic<br />

<strong>noise</strong> and myocardial infarction (Babisch et al., 1994). Fig. 4.4 shows the<br />

results of the three aircraft <strong>noise</strong> studies carried out in Amsterdam, Okinawa and<br />

Stockholm (Knipschild, 1977a; Rosenlund et al., 2001; Matsui et al., 2004). The<br />

graph clearly indicates that the results are too heterogeneous to derive a pooled<br />

dose–response curve. However, all three studies show an increase in risk with<br />

increasing <strong>noise</strong> level.<br />

Studies that are not given a high ranking according to the above mentioned criteria,<br />

however, may serve as additional sources of in<strong>for</strong>mation to support the evidence<br />

of the conclusions being made on the basis of this review. This is illustrated<br />

in Fig. 4.5. The entries are relative risks (centre of the bars) with 95% confidence<br />

intervals (the bars) <strong>for</strong> dichotomous comparisons of <strong>noise</strong> exposure<br />

(extreme groups or high vs. low). A relative consistent shift of the bars to relative<br />

risks greater than 1 can be seen. The dark-shaded bars in the diagram refer to<br />

studies where the <strong>noise</strong> exposure was determined objectively (<strong>noise</strong> levels), the<br />

Amsterdam<br />

Stockholm<br />

Okinawa<br />

Fig. 4.4<br />

Association between<br />

aircraft <strong>noise</strong> level and the<br />

prevalence of hypertension<br />

Relative risk<br />

2.2<br />

2<br />

1.8<br />

1.6<br />

1.4<br />

1.2<br />

1<br />

0.8<br />

46–50<br />

51–55<br />

56–60<br />

61–65<br />

66–70<br />

71–75<br />

76–80<br />

Approx.Lday dB(A)<br />

NIGHT NOISE GUIDELINES FOR EUROPE

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