Global Tuberculosis Report -- 2012.pdf

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the Republic of Moldova, Romania, the Russian Federation,Tajikistan, Turkmenistan, Ukraine, Uzbekistan.High-income countries: Andorra, Aruba, Australia,Austria, the Bahamas, Bahrain, Barbados, Belgium, Bermuda,Brunei Darussalam, Canada, the Cayman Islands,China, Hong Kong SAR, China Macao SAR, Croatia,Cyprus, the Czech Republic, Denmark, Equatorial Guinea,Estonia, Finland, France, French Polynesia, Germany,Greece, Greenland, Guam, Hungary, Iceland, Ireland,Israel, Italy, Japan, Kuwait, Luxembourg, Malta, Monaco,the Netherlands, the Netherlands Antilles, New Caledonia,New Zealand, Northern Mariana Islands, Norway,Oman, Poland, Portugal, Puerto Rico, Qatar, the Republicof Korea, Saint Kitts and Nevis, San Marino, SaudiArabia, Singapore, Slovakia, Slovenia, Spain, Sweden,Switzerland, Trinidad and Tobago, the Turks and CaicosIslands, US Virgin Islands, United Arab Emirates, theUnited Kingdom, the United States.Eastern Mediterranean: Afghanistan, Egypt, Iran(Islamic Republic of), Iraq, Jordan, Lebanon, Libya,Morocco, Pakistan, Syrian Arab Republic, Tunisia, WestBank and the Gaza Strip, Yemen,Latin America: Anguilla, Antigua and Barbuda, Argentina,Belize, Bolivia (Plurinational State of), Bonaire,Saint Eustatius and Saba, Brazil, British Virgin Islands,Chile, Colombia, Costa Rica, Cuba, Curaçao, Dominica,the Dominican Republic, Ecuador, El Salvador, Grenada,Guatemala, Guyana, Haiti, Honduras, Jamaica, Mexico,Montserrat, Nicaragua, Panama, Paraguay, Peru, SaintKitts and Nevis, Saint Lucia, Saint Vincent and the Grenadines,Sint Maarten (Dutch part), Suriname, Uruguay,Venezuela (Bolivarian Republic of).South East Asia: Bangladesh, Bhutan, DemocraticPeople’s Republic of Korea, India, Indonesia, Maldives,Myanmar, Nepal, Sri Lanka, Thailand, Timor-Leste.West Pacific: American Samoa, Cambodia, China, CookIslands, Fiji, Kiribati, Lao People’s Democratic Republic,Malaysia, Marshall Islands, Micronesia (Federated Stateof), Mongolia, Nauru, Niue, Palau, Papua New Guinea,the Philippines, Samoa, Solomon Islands, Tokelau, Tonga,Tuvalu, Vanuatu, Viet Nam, Wallis and Futuna Islands.GLOBAL TUBERCULOSIS REPORT 2012 103
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GLOBALTUBERCULOSISREPORT2012
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ContentsAbbreviationsivAcknowledgem
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AcknowledgementsThis report on glob
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WHO Western Pacific RegionShalala A
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Executive SummaryThe World Health O
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CHAPTER 1IntroductionBOX 1.1Basic f
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TABLE 1.1 Targets for the scale-up
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TABLE 1.2 Reporting of data in the
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BOX 2.1Uncertainty in estimates of
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TABLE 2.2 Estimated burden of disea
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FIGURE 2.5 Estimated TB incidence r
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FIGURE B2.2.1Reporting of notificat
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FIGURE 2.8Estimated TB incidence ra
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FIGURE 2.11 Countries (in blue) for
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FIGURE 2.12 Trends in estimated TB
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● producing and widely disseminat
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FIGURE 2.16 Progress in global cove
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BOX 2.6Efforts by the Task Force to
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CHAPTER 3TB case notificationsand t
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BOX 3.1 1Definitions of TB casesDef
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TABLE 3.3 Contribution of public-pr
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BOX 3.4Integrating community-based
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TABLE 3.4 Estimates of the case det
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TABLE 3.5 Treatment success for new
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CHAPTER 4Drug-resistant TBKEY FACTS
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FIGURE 4.2 Percentage of new TB cas
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BOX 4.1Frequencies of resistance to
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FIGURE 4.6 Number of MDR-TB cases e
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FIGURE 4.7Notified cases of MDR-TB
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egimens globally, providing more su
Page 62 and 63: 5.1 Funding for TB care and control
Page 64 and 65: TABLE 5.2 NTP budgets, available fu
Page 66 and 67: FIGURE 5.5Trends in domestic and do
Page 68 and 69: FIGURE 5.6Domestic funding as a per
Page 70 and 71: FIGURE 5.8Cost per TB patient succe
Page 72 and 73: FIGURE 5.10 Total cost and unit cos
Page 74 and 75: ● The 14 countries not included i
Page 76 and 77: on public health by an external Exp
Page 78 and 79: evised as a result of the introduct
Page 80 and 81: TABLE 6.2 Incorporation of WHO poli
Page 82 and 83: FIGURE 6.3The Supranational Referen
Page 84 and 85: of TB disease by 65%, irrespective
Page 86 and 87: FIGURE 7.3Percentage of TB patients
Page 88 and 89: BOX 7.1Accelerating progress in pro
Page 90 and 91: TABLE 7.2 Assumptions used to estim
Page 92 and 93: FIGURE 8.1 The development pipeline
Page 94 and 95: sputum specimens and TB isolates fr
Page 96 and 97: cal trial sites and building labora
Page 98: new TB vaccine candidate. A Phase I
Page 102 and 103: This annex explains the methods tha
Page 104 and 105: 2011. On average, 15 data points we
Page 106 and 107: may suffer from biases. These biase
Page 108 and 109: TABLE A1.3Parameter estimates used
Page 110 and 111: 5. Estimates of TB prevalence, 1990
Page 114: ANNEX 2Country profiles
Page 117 and 118: BANGLADESHPopulation 2011 150 milli
Page 119 and 120: CAMBODIAPopulation 2011 14 millionH
Page 121 and 122: DEMOCRATIC REPUBLIC OF THE CONGOPop
Page 123 and 124: INDIAPopulation 2011 1 241 millionH
Page 125 and 126: KENYAPopulation 2011 42 millionHIGH
Page 127 and 128: MYANMARPopulation 2011 48 millionHI
Page 129 and 130: PAKISTANPopulation 2011 177 million
Page 131 and 132: RUSSIAN FEDERATIONPopulation 2011 1
Page 133 and 134: THAILANDPopulation 2011 70 millionH
Page 135 and 136: UNITED REPUBLIC OF TANZANIAPopulati
Page 137 and 138: ZIMBABWEPopulation 2011 13 millionH
Page 140 and 141: WHO AFRICAN REGIONPopulation 2011 8
Page 142 and 143: WHO EASTERN MEDITERRANEAN REGIONPop
Page 144 and 145: WHO SOUTH-EAST ASIA REGIONPopulatio
Page 146: ANNEX 4Global, regionaland country-
Page 149 and 150: Estimates of mortality, prevalence
Page 151 and 152: YEARPOPULATION(MILLIONS)INCIDENCE (
Page 153 and 154: TREATMENT SUCCESS (%) a1995-2010YEA
Page 155 and 156: MALEFEMALEYEAR 0-14 15-24 25-34 35-
Page 157 and 158: Estimates of mortality, prevalence
Page 159 and 160: YEARPOPULATION(MILLIONS)MORTALITY (
Page 161 and 162: YEARPOPULATION(MILLIONS)INCIDENCE (
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YEARPOPULATION(MILLIONS)INCIDENCE (
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NEW AND RELAPSENOTIFICATION RATE a1
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TREATMENT SUCCESS (%) a1995-2010YEA
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-% OF TB PATIENTS WITHKNOWN HIV STA
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YEARTOTALCONFIRMEDCASES OFMDR-TB aE
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MALEFEMALEYEAR 0-14 15-24 25-34 35-
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SMEAR LABS % OF SMEARPER 100K LABS
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Estimates of mortality, prevalence
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YEARPOPULATION(MILLIONS)MORTALITY (
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WESTERN PACIFIC REGIONTable A4.1 Es
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MORTALITY (EXCLUDING HIV) PREVALENC
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INCIDENCE (INCLUDING HIV) INCIDENCE
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% OF COHORTTREATMENT SUCCESS (%) a1
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% OF COHORTTREATMENT SUCCESS (%) a1
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The World Health Organization monit
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