Global Tuberculosis Report -- 2012.pdf

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NEW AND RELAPSENOTIFICATION RATE aYEARNEW ANDNEW CASESSMEAR- SMEAR-NEGATIVE/POSITIVE UNKNOWNEXTRA-RE-TREAT EXCL.OTHER RELAPSEPULMONARY RELAPSETOTALRETREATHISTORYUNKNOWN% SMEAR-POS AMONGNEW PULM1990–2011RELAPSEAlgeria 1990 11 607 –1995 13 507 5 735 2 256 5 065 451 451 722000 18 572 8 328 2 019 7 758 467 80 547 802005 21 336 8 654 1 651 10 216 267 548 165 713 842009 21 701 8 402 1 691 10 888 230 490 122 612 0 832010 22 336 8 299 1 770 11 770 0 497 194 691 0 82• 46 60 • 2011 21 429 7 790 1 753 11 444 0 442 168 610 0 82Angola 1990 10 271 –1995 5 143 3 804 1 631 266 134 134 702000 16 062 9 053 5 367 1 102 540 540 632005 37 175 20 410 12 467 2 569 1 729 1 142 2 871 622009 41 221 22 488 13 755 2 580 0 2 398 1 465 3 863 0 622010 44 655 21 146 17 285 3 780 2 444 5 332 7 776 55• 99 241 • 2011 47 240 21 703 18 380 4 399 0 2 758 1 686 4 444 0 54Benin 1990 2 074 1 410 310 182 172 49 221 821995 2 400 1 839 281 212 68 68 872000 2 697 2 277 130 199 91 189 280 952005 3 270 2 739 96 285 150 187 337 972009 3 878 2 960 338 418 0 162 109 271 0 902010 3 756 2 973 296 367 0 120 85 205 0 91• 43 46 • 2011 4 212 3 331 329 398 0 154 108 262 0 91Botswana 1990 2 938 –1995 5 665 1 903 2 885 720 147 147 402000 9 292 3 091 4 789 1 231 181 1 058 1 239 392005 10 058 3 170 5 166 1 220 502 46 548 382009 8 362 3 144 3 393 1 429 0 396 726 1 122 0 482010 7 013 3 295 2 055 1 210 0 453 619 1 072 0 62• 213 325 • 2011 6 603 2 669 1 983 1 213 0 738 130 868 0 57Burkina Faso 1990 1 497 –1995 2 572 1 028 195 195 45 45 842000 2 331 1 545 196 502 88 90 178 0 892005 3 478 2 290 367 571 90 160 167 327 0 862009 4 716 3 061 679 671 92 213 395 608 0 822010 4 800 3 041 736 729 77 217 335 552 0 81• 16 31 • 2011 5 286 3 450 692 742 175 227 257 484 0 83Burundi 1990 4 575 –1995 3 326 1 121 908 1 116 181 181 552000 6 421 3 159 1 489 1 568 0 205 20 225 0 682005 6 585 3 262 1 160 2 089 0 74 42 116 0 742009 7 277 3 974 1 207 1 880 24 192 46 238 0 772010 7 611 4 590 963 1 826 8 224 108 332 0 83• 82 79 • 2011 6 742 4 060 799 1 649 5 229 86 315 0 84Cameroon 1990 5 892 –1995 3 292 2 896 142 18 236 236 952000 5 251 3 960 625 415 251 251 862005 21 499 13 001 5 021 2 461 0 1 016 574 1 590 0 722009 24 662 14 635 5 780 3 190 0 1 057 512 1 569 0 722010 24 073 14 464 5 437 3 157 0 1 015 479 1 494 0 73• 48 122 • 2011 24 533 14 927 4 941 3 597 0 1 068 593 1 661 0 75Cape Verde 1990 221 –1995 303 111 150 12 30 30 432000 –2005 292 135 93 43 0 21 13 34 0 592009 332 172 94 53 0 13 20 33 0 652010 356 186 98 54 18 9 27 65• 63 76 • 2011 380 182 127 54 0 17 10 27 0 59Central African 1990 2 124 –Republic 1995 3 339 1 794 964 393 188 188 652000 –2005 3 210 2 153 608 286 0 163 128 291 0 782009 8 743 5 132 1 841 1 394 376 253 629 742010 6 643 3 638 1 598 1 079 24 304 117 421 0 69• 72 125 • 2011 5 611 3 479 964 876 60 232 113 345 0 78Chad 1990 2 591 –1995 3 186 2 002 518 463 203 203 792000 –2005 6 311 2 516 2 419 1 055 321 194 515 512009 8 411 3 820 2 949 1 206 0 436 240 676 0 562010 9 452 3 833 3 746 1 217 193 463 245 708 0 51• 43 91 • 2011 10 505 4 434 4 211 1 033 249 578 269 847 0 51Comoros 1990 140 –1995 123 103 10 7 7 7 912000 120 87 14 15 4 1 5 862005 111 79 14 16 0 2 1 3 0 852009 120 76 15 24 0 5 1 6 8 842010 –• 32 16 • 2011 117 62 13 28 5 9 2 11 0 83Congo 1990 591 –1995 3 615 2 013 849 675 78 78 702000 9 239 4 218 2 016 2 810 169 650 819 682005 9 853 3 640 3 249 2 665 299 108 407 532009 9 765 3 433 3 398 2 653 0 281 170 451 0 502010 10 150 3 568 3 545 2 692 345 171 516 50• 25 265 • 2011 10 975 3 716 3 930 2 990 0 339 168 507 0 49Côte d'Ivoire 1990 7 841 –1995 11 988 8 254 1 508 1 577 649 649 852000 15 094 10 276 1 616 2 756 0 446 447 893 0 862005 19 681 12 496 2 315 4 235 0 635 345 980 0 842009 22 571 14 300 2 321 4 952 0 998 438 1 436 0 862010 22 708 14 131 2 381 5 179 0 1 017 502 1 519 0 86• 63 112 • 2011 22 476 14 416 2 316 4 729 0 1 015 444 1 459 0 86Democratic 1990 21 131 –Republic 1995 42 819 20 914 7 953 9 112 2 891 2 891 72of the Congo 2000 61 024 36 513 8 089 13 785 2 637 2 637 822005 97 075 65 040 9 959 18 494 3 582 2 483 6 065 872009 111 709 73 078 12 968 21 313 4 350 4 316 8 666 852010 114 170 73 653 14 039 22 340 0 4 138 4 466 8 604 0 84• 58 163 • 2011 110 132 71 321 13 471 21 579 3 761 4 158 7 919 84Equatorial 1990 260 –Guinea 1995 306 219 45 41 1 1 832000 –2005 –2009 707 490 109 77 0 31 13 44 0 822010 820 579 98 109 0 34 33 67 0 86• 70 123 • 2011 883 611 118 131 0 23 30 53 0 84AFRICAN REGIONaRates are per 100 000 population.GLOBAL TUBERCULOSIS REPORT 2012 Data can be downloaded from www.who.int/tb/data 155
NEW AND RELAPSENOTIFICATION RATE a1990–2011YEARNEW ANDRELAPSENEW CASESSMEAR- SMEAR-NEGATIVE/POSITIVE UNKNOWNEXTRA-RE-TREAT EXCL.OTHER RELAPSEPULMONARY RELAPSETOTALRETREATHISTORYUNKNOWN% SMEAR-POS AMONGNEW PULMEritrea 1990 3 699 –1995 21 453 18 205 3 248 –2000 6 652 590 5 332 683 47 20 67 102005 3 549 687 1 764 1 001 97 27 124 36 282009 2 904 802 1 123 890 0 89 118 207 0 422010 2 870 832 1 115 836 0 87 121 208 0 43• 117 56 • 2011 3 049 835 1 163 888 60 103 44 147 0 42Ethiopia 1990 88 634 –1995 26 034 9 040 8 888 7 763 343 343 502000 91 101 30 510 30 565 28 907 1 119 1 658 2 777 502005 124 262 38 525 39 816 43 675 2 246 873 3 119 492009 148 936 44 396 52 053 50 228 2 259 1 285 3 544 462010 154 694 46 634 54 979 50 417 0 2 664 2 234 4 898 46• 183 185 • 2011 156 539 49 594 55 497 49 305 0 2 143 2 478 4 621 0 47Gabon 1990 917 –1995 1 115 486 517 68 44 44 482000 –2005 2 512 1 042 1 071 241 158 99 257 492009 3 073 1 244 1 414 246 0 169 486 655 0 472010 3 473 1 560 1 366 379 0 168 390 558 317 53• 99 287 • 2011 4 404 1 740 1 959 384 0 321 512 833 0 47Gambia 1990 –1995 1 023 778 171 68 6 6 822000 –2005 2 031 1 127 749 78 0 77 89 166 0 602009 2 145 1 316 622 141 0 66 41 107 682010 2 070 1 344 462 143 81 40 41 81 0 74• 0 127 • 2011 2 248 1 375 673 199 1 138 139 0 67Ghana 1990 6 407 –1995 8 636 2 638 1 225 109 159 159 682000 10 933 7 316 2 500 615 502 502 752005 12 124 7 505 3 068 1 019 532 532 712009 14 892 8 255 4 734 1 437 0 466 394 860 0 642010 14 607 7 656 5 068 1 400 0 483 538 1 021 0 60• 43 62 • 2011 15 389 7 616 5 875 1 471 427 451 878 56Guinea 1990 1 988 –1995 3 523 2 263 527 620 55 55 812000 5 440 3 920 430 938 152 294 446 902005 6 863 5 479 524 629 231 227 458 912009 8 357 5 377 1 021 1 611 0 348 241 589 16 842010 11 038 7 041 1 472 2 077 86 362 286 648 0 83• 35 111 • 2011 11 359 6 934 1 446 2 284 273 422 247 669 83Guinea-Bissau 1990 1 163 –1995 1 613 956 714 19 59 59 572000 1 273 526 600 57 90 90 472005 1 774 1 132 522 24 0 96 42 138 0 682009 2 171 1 310 786 16 0 59 17 76 0 622010 2 183 1 409 636 22 0 116 76 192 0 69• 114 133 • 2011 2 063 1 230 644 63 0 126 7 133 0 66Kenya 1990 11 788 6 800 1001995 28 142 13 934 9 676 3 468 1 064 1 064 592000 64 159 28 773 24 143 9 118 1 773 704 2 477 542005 102 680 40 389 43 772 15 265 3 254 5 721 8 975 482009 102 997 37 402 44 514 17 438 3 643 7 068 10 711 462010 99 272 36 260 41 962 17 382 0 3 668 6 811 10 479 0 46• 50 234 • 2011 97 320 37 085 39 810 17 069 0 3 356 6 661 10 017 0 48Lesotho 1990 2 525 –1995 5 181 1 361 2 685 653 147 147 342000 9 746 3 041 2 838 2 520 385 1 096 1 481 522005 10 802 4 280 4 063 2 020 439 602 1 041 512009 12 213 3 976 5 083 2 486 668 1 302 1 970 442010 11 674 3 600 5 331 2 222 521 1 464 1 985 40• 154 521 • 2011 11 432 3 510 5 343 2 099 480 1 196 1 676 40Liberia 1990 –1995 1 393 1 154 119 120 912000 1 500 1 021 285 187 7 25 32 782005 3 432 2 167 575 657 33 24 57 792009 5 918 3 796 1 022 1 023 0 77 46 123 0 792010 6 597 3 750 1 385 1 363 0 99 71 170 0 73• 0 191 • 2011 7 906 4 261 1 967 1 612 0 66 59 125 0 68Madagascar 1990 6 261 –1995 21 616 8 026 987 2 219 596 596 892000 –2005 18 993 13 056 1 287 3 634 0 1 016 482 1 498 0 912009 22 758 15 729 1 639 3 990 0 1 400 689 2 089 0 912010 24 432 16 795 1 657 4 545 0 1 435 674 2 109 0 91• 56 122 • 2011 26 019 17 927 1 726 4 851 1 515 703 2 218 91Malawi 1990 12 395 4 301 5 827 1 885 382 382 421995 19 155 6 285 7 054 5 257 551 551 472000 23 604 8 260 8 846 5 734 764 0 764 482005 25 491 8 443 10 132 5 823 1 093 2 119 3 212 452009 22 674 7 623 9 297 4 966 0 788 1 682 2 470 0 452010 21 092 7 240 8 245 4 857 0 750 1 444 2 194 47• 132 126 • 2011 19 361 7 003 6 612 5 076 670 1 493 2 163 51Mali 1990 2 933 –1995 3 087 1 866 609 459 153 153 752000 4 216 2 527 797 653 239 239 762005 4 704 3 530 482 492 200 180 380 0 882009 6 611 5 163 429 818 0 201 224 425 0 922010 5 291 3 686 481 926 0 198 157 355 0 88• 34 34 • 2011 5 428 3 777 491 984 176 145 321 88Mauritania 1990 5 284 –1995 3 849 2 074 800 455 520 520 722000 3 067 1 583 687 580 580 358 938 702005 2 162 1 155 454 403 0 150 56 206 0 722009 2 640 1 555 444 483 0 158 24 182 0 782010 2 461 1 422 390 524 0 125 28 153 78• 265 50 • 2011 1 776 1 009 222 458 0 87 16 103 28 82Mauritius 1990 119 –1995 131 113 8 12 2 2 932000 160 115 14 23 8 4 12 892005 125 110 4 8 3 2 5 962009 115 98 7 6 0 4 1 5 0 932010 122 105 5 6 0 6 1 7 0 95• 11 9 • 2011 114 100 3 8 0 3 2 5 0 97aRates are per 100 000 population.156 Data can be downloaded from www.who.int/tb/data GLOBAL TUBERCULOSIS REPORT 2012
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GLOBALTUBERCULOSISREPORT2012
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ContentsAbbreviationsivAcknowledgem
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AcknowledgementsThis report on glob
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WHO Western Pacific RegionShalala A
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Executive SummaryThe World Health O
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CHAPTER 1IntroductionBOX 1.1Basic f
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TABLE 1.1 Targets for the scale-up
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TABLE 1.2 Reporting of data in the
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BOX 2.1Uncertainty in estimates of
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TABLE 2.2 Estimated burden of disea
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FIGURE 2.5 Estimated TB incidence r
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FIGURE B2.2.1Reporting of notificat
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FIGURE 2.8Estimated TB incidence ra
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FIGURE 2.11 Countries (in blue) for
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FIGURE 2.12 Trends in estimated TB
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● producing and widely disseminat
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FIGURE 2.16 Progress in global cove
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BOX 2.6Efforts by the Task Force to
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CHAPTER 3TB case notificationsand t
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BOX 3.1 1Definitions of TB casesDef
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TABLE 3.3 Contribution of public-pr
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BOX 3.4Integrating community-based
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TABLE 3.4 Estimates of the case det
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TABLE 3.5 Treatment success for new
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CHAPTER 4Drug-resistant TBKEY FACTS
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FIGURE 4.2 Percentage of new TB cas
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BOX 4.1Frequencies of resistance to
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FIGURE 4.6 Number of MDR-TB cases e
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FIGURE 4.7Notified cases of MDR-TB
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egimens globally, providing more su
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5.1 Funding for TB care and control
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TABLE 5.2 NTP budgets, available fu
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FIGURE 5.5Trends in domestic and do
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FIGURE 5.6Domestic funding as a per
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FIGURE 5.8Cost per TB patient succe
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FIGURE 5.10 Total cost and unit cos
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● The 14 countries not included i
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on public health by an external Exp
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evised as a result of the introduct
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TABLE 6.2 Incorporation of WHO poli
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FIGURE 6.3The Supranational Referen
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of TB disease by 65%, irrespective
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FIGURE 7.3Percentage of TB patients
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BOX 7.1Accelerating progress in pro
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TABLE 7.2 Assumptions used to estim
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FIGURE 8.1 The development pipeline
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sputum specimens and TB isolates fr
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cal trial sites and building labora
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new TB vaccine candidate. A Phase I
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This annex explains the methods tha
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2011. On average, 15 data points we
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may suffer from biases. These biase
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TABLE A1.3Parameter estimates used
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5. Estimates of TB prevalence, 1990
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the Republic of Moldova, Romania, t
Page 116 and 117: AFGHANISTANPopulation 2011 32 milli
Page 118 and 119: BRAZILPopulation 2011 197 millionHI
Page 120 and 121: CHINAPopulation 2011 1 348 millionH
Page 122 and 123: ETHIOPIAPopulation 2011 85 millionH
Page 124 and 125: INDONESIAPopulation 2011 242 millio
Page 126 and 127: MOZAMBIQUEPopulation 2011 24 millio
Page 128 and 129: NIGERIAPopulation 2011 162 millionH
Page 130 and 131: PHILIPPINESPopulation 2011 95 milli
Page 132 and 133: SOUTH AFRICAPopulation 2011 50 mill
Page 134 and 135: UGANDAPopulation 2011 35 millionHIG
Page 136 and 137: VIET NAMPopulation 2011 89 millionH
Page 138: ANNEX 3Regional profiles
Page 141 and 142: WHO REGION OF THE AMERICASPopulatio
Page 143 and 144: WHO EUROPEAN REGIONPopulation 2011
Page 145 and 146: WHO WESTERN PACIFIC REGIONPopulatio
Page 148 and 149: SUMMARY BY WHO REGIONTable A4.1 Est
Page 150 and 151: MORTALITY (EXCLUDING HIV) PREVALENC
Page 152 and 153: NEW AND RELAPSENOTIFICATION RATE aY
Page 154 and 155: -% OF TB PATIENTS WITHKNOWN HIV STA
Page 156 and 157: AFRICAN REGIONTable A4.1 Estimates
Page 162 and 163: INCIDENCE (INCLUDING HIV) INCIDENCE
Page 166 and 167: NEW AND RELAPSENOTIFICATION RATE a1
Page 168 and 169: TREATMENT SUCCESS (%) a1995-2010YEA
Page 176 and 177: YEARTOTALCONFIRMEDCASES OFMDR-TB aE
Page 178 and 179: MALEYEAR 0-14 15-24 25-34 35-44 45-
Page 180 and 181: REGION OF THE AMERICASTable A4.1 Es
Page 192 and 193: % OF COHORTTREATMENT SUCCESS (%) a1
Page 200 and 201: YEARTOTALCONFIRMEDCASES OFMDR-TB aE
Page 202 and 203: MALEFEMALEYEAR 0-14 15-24 25-34 35-
Page 204 and 205: EASTERN MEDITERRANEAN REGIONTable A
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% OF COHORTTREATMENT SUCCESS (%) a1
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-% OF TB PATIENTS WITHKNOWN HIV STA
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MALEFEMALEYEAR 0-14 15-24 25-34 35-
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EUROPEAN REGIONTable A4.1 Estimates
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MORTALITY (EXCLUDING HIV) PREVALENC
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INCIDENCE (INCLUDING HIV) INCIDENCE
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INCIDENCE (INCLUDING HIV) INCIDENCE
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NEW AND RELAPSENOTIFICATION RATE a1
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YEARTOTALCONFIRMEDCASES OFMDR-TB aE
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SOUTH-EAST ASIA REGIONTable A4.1 Es
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SMEAR LABS % OF SMEARPER 100K LABS
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Estimates of mortality, prevalence
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YEARPOPULATION(MILLIONS)MORTALITY (
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YEARPOPULATION(MILLIONS)INCIDENCE (
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YEARPOPULATION(MILLIONS)INCIDENCE (
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TREATMENT SUCCESS (%) a1995-2010YEA
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TREATMENT SUCCESS (%) a1995-2010YEA
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SMEAR LABS % OF SMEARPER 100K LABS
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