Global Tuberculosis Report -- 2012.pdf

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MALEFEMALEYEAR 0–14 15–24 25–34 35–44 45–54 55–64 65+0–14 15–24 25–34 35–44 45–54 55–64 65+UN-KNOWNUN-KNOWNMALE:FEMALERATIOSlovenia 1995 1 13 39 63 36 26 27 0 7 24 11 9 5 42 2.12000 0 3 11 36 22 14 17 0 3 9 3 4 3 20 2.52005 0 4 10 16 15 11 14 0 0 4 4 6 5 4 16 0 1.82010 0 4 7 10 9 6 12 0 0 1 5 2 4 1 3 0 3.02011 0 3 9 16 12 8 5 0 0 0 5 4 2 1 17 0 1.8Spain 1995 22 132 337 242 150 112 228 23 90 129 64 39 34 98 2.62000 –2005 13 166 394 367 230 140 230 2 10 142 252 151 63 24 108 2 2.12010 6 139 306 291 286 146 184 1 14 130 251 151 54 23 76 0 1.92011 15 135 325 292 277 162 197 2 15 142 249 161 75 30 100 0 1.8Sweden 1995 1 5 12 8 5 4 27 0 10 13 5 5 4 14 1.22000 0 9 10 12 11 4 25 1 9 8 10 2 2 15 1.52005 0 7 21 16 10 5 16 0 1 10 15 12 5 3 13 0 1.32010 1 10 28 8 5 5 13 0 2 9 16 11 4 2 3 0 1.52011 1 14 15 12 8 3 8 0 0 12 9 10 2 2 3 0 1.6Switzerland 1995 0 12 23 26 23 13 27 1 13 20 9 1 2 15 2.02000 0 5 17 10 7 6 6 0 1 8 11 7 2 1 5 0 1.52005 2 8 10 11 11 2 7 0 0 6 11 8 3 1 4 0 1.52010 0 6 12 9 6 5 8 0 0 7 15 6 4 1 3 0 1.32011 2 8 16 10 13 7 3 0 2 6 13 2 4 2 2 0 1.9Tajikistan 1995 –2000 –2005 8 308 279 164 104 54 48 0 26 225 185 151 89 43 53 0 1.22010 12 398 366 214 129 93 74 0 23 320 272 111 109 87 82 0 1.32011 8 343 365 181 128 75 77 0 31 314 229 104 100 105 114 0 1.2The Former 1995 2 15 42 45 33 29 24 2 32 30 20 11 17 17 1.5Yugoslav Republic 2000 5 8 14 20 19 20 14 1 15 14 17 5 5 10 1.5of Macedonia 2005 2 14 20 23 20 18 13 1 2 17 13 10 7 5 13 0 1.72010 0 6 19 24 24 12 11 0 0 9 12 7 7 4 6 0 2.12011 3 17 11 19 21 10 6 0 1 14 9 6 3 1 11 0 1.9Turkey 1995 –2000 –2005 33 1 148 1 295 1 028 963 534 429 0 50 699 474 243 175 166 213 0 2.72010 23 631 779 703 778 514 407 0 33 485 384 193 141 101 203 0 2.52011 22 550 693 608 696 482 412 0 25 409 385 195 117 121 212 0 2.4Turkmenistan 1995 1 11 188 0 79 30 0 2 15 146 0 47 25 0 1.32000 16 103 185 144 127 31 21 19 73 140 76 31 34 17 1.62005 2 148 181 146 97 51 13 0 3 100 101 72 46 27 8 0 1.82010 1 130 212 183 141 51 26 2 112 112 74 46 38 25 1.82011 –Ukraine 1995 10 385 1 076 2 064 1 515 1 087 437 21 314 380 327 182 185 280 3.92000 21 693 1 552 2 385 2 007 1 062 532 41 487 590 447 298 218 405 3.32005 –2010 7 417 2 559 2.92011 8 539 1 991 2 209 1 796 881 377 0 11 348 741 603 388 230 380 0 2.9United Kingdom of 1995 –Great Britain and 2000 8 86 130 96 87 75 138 9 95 114 60 31 31 67 1.5Northern Ireland 2005 9 135 200 166 95 95 124 0 14 115 163 80 39 28 83 1 1.62010 7 132 169 135 108 60 108 0 15 110 131 81 42 40 58 0 1.52011 3 137 193 137 97 69 100 0 19 120 129 75 45 26 49 0 1.6Uzbekistan 1995 –2000 6 351 749 510 346 213 107 11 261 547 288 213 112 111 1.52005 25 596 831 723 522 263 313 40 538 597 375 288 217 367 1.42010 8 487 574 529 479 293 297 0 22 365 512 308 248 239 350 0 1.32011 8 378 493 453 440 306 253 0 11 335 418 233 245 293 332 0 1.2EUROPEAN REGIONGLOBAL TUBERCULOSIS REPORT 2012 Data can be downloaded from www.who.int/tb/data 237
SMEAR LABS % OF SMEARPER 100K LABS USINGPOPULATION LED aCULTURELABS PER 5MPOPULATIONLABORATORIESDST b LABSPER 5MPOPULATIONLPA c LABSPER 5MPOPULATIONNUMBER OFLABS USINGXPERT MTB/RIFSECOND-LINE DSTAVAILABLENRL dFREE THROUGH NTPTB DIAGNOSISFIRST-LINEDRUGSTB NOTIF.RIFAMPICINRATE PERUSED100 000THROUGHOUTHEALTH-CARETREATMENTWORKERSAlbania 0.5 0 1.6 1.6 1.6 0 No yesYes (if TB isconfirmed)yes YesAndorra 9.3 – 464.2 464.2In and outof countryyes Yes (all suspects) yes YesArmenia 1.0 0 1.6 1.6 1.6 0 In country yes Yes (all suspects) yes YesAustria –Azerbaijan 0.7 – 3.2 1.1 1.1 1 yes Yes (all suspects) yes YesBelarus 2.1 2 21.4 10.5 0.5 0 In country yes Yes (all suspects) yes Yes 49Belgium 1.1 – 53.0 7 3.7 6 yes Yes (all suspects) yes YesBosnia and Herzegovina 0.4 13 17.3 5.3 4 0Out ofcountryyes Yes (all suspects) yes YesBulgaria 0.5 – 22.2 8.7 2 0 In country yes Yes (all suspects) yes YesCroatia 0.3 0 15.9 6.8 1.1 1 yes Yes (all suspects) yes YesCyprus –Czech Republic 0.5 – 22.8 8.1 8.1 In country yes Yes (all suspects) yes YesDenmark –Estonia 0.4 40 7.5 7.5 7.5 2 In country yes Yes (all suspects) yes Yes 12Finland 0.4 – 10.2 0.9 4.6 3 yes Yes (all suspects) yes YesFrance – In country yes Yes (all suspects) yes YesGeorgia 0.7 – 2.3 1.2 1.2 1 In country yes Yes (all suspects) yes YesGermany 0.3 – 11.5 5.1 yes Yes (all suspects) yes YesGreece –Greenland –Hungary 0.1 0 6.5 3.5 1 2 In country yes Yes (all suspects) yes YesIceland 0.3 100 15.4 15.4 15.4 0Out ofYes (if TB isyescountryconfirmed)yes YesIreland 0.3 8 14.4 3.3 3.3 2Out ofcountryyes Yes (all suspects) No YesIsrael 0.3 – 12.6 1.3 0.7 1 In country yes Yes (all suspects) yes YesItaly –Kazakhstan 2.9 0 30.9 6.8 3.1 0 No yes Yes (all suspects) yes YesKyrgyzstan 2.3 0 3.7 2.8 yes Yes (all suspects) yes YesLatvia 0.7 0 8.9 2.2 2.2 1 In country yes Yes (all suspects) yes YesLithuania 0.4 0 9.1 9.1 3 5In and outof countryyes Yes (all suspects) yes Yes 32Luxembourg 0.2 100 9.7 9.7 9.7 1Out ofcountryyes Yes (all suspects) yes YesMalta 0.2 – 12.0 0 0Out ofcountryNo Yes (all suspects) yes YesMonaco –Montenegro 0.2 0 7.9 7.9 0 0Out ofYes (if TB isNocountryconfirmed)yes YesNetherlands 0.3 – 11.1 3 0.3 2 In country yes Yes (all suspects) No YesNorway 0.4 0 10.2 3 4.1 0In and outof countryyes Yes (all suspects) yes YesPoland 0.2 0 11.1 6.1 1.4 3 In country yes Yes (all suspects) yes YesPortugal –Republic of Moldova 1.7 – 5.6 5.6 4.2 yes Yes (all suspects) yes YesRomania 0.5 0 16.3 10 0 0 In country yes Yes (all suspects) yes Yes 57Russian Federation 2.6 – 4.1 In country No Yes (all suspects) yes Yes 185San Marino –Serbia 0.3 0 14.7 2 0.5 0Out ofYes (if TB isyescountryconfirmed)yes Yes 11Slovakia
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GLOBALTUBERCULOSISREPORT2012
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ContentsAbbreviationsivAcknowledgem
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AcknowledgementsThis report on glob
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WHO Western Pacific RegionShalala A
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Executive SummaryThe World Health O
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CHAPTER 1IntroductionBOX 1.1Basic f
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TABLE 1.1 Targets for the scale-up
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TABLE 1.2 Reporting of data in the
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BOX 2.1Uncertainty in estimates of
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TABLE 2.2 Estimated burden of disea
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FIGURE 2.5 Estimated TB incidence r
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FIGURE B2.2.1Reporting of notificat
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FIGURE 2.8Estimated TB incidence ra
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FIGURE 2.11 Countries (in blue) for
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FIGURE 2.12 Trends in estimated TB
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● producing and widely disseminat
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FIGURE 2.16 Progress in global cove
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BOX 2.6Efforts by the Task Force to
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CHAPTER 3TB case notificationsand t
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BOX 3.1 1Definitions of TB casesDef
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TABLE 3.3 Contribution of public-pr
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BOX 3.4Integrating community-based
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TABLE 3.4 Estimates of the case det
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TABLE 3.5 Treatment success for new
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CHAPTER 4Drug-resistant TBKEY FACTS
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FIGURE 4.2 Percentage of new TB cas
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BOX 4.1Frequencies of resistance to
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FIGURE 4.6 Number of MDR-TB cases e
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FIGURE 4.7Notified cases of MDR-TB
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egimens globally, providing more su
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5.1 Funding for TB care and control
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TABLE 5.2 NTP budgets, available fu
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FIGURE 5.5Trends in domestic and do
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FIGURE 5.6Domestic funding as a per
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FIGURE 5.8Cost per TB patient succe
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FIGURE 5.10 Total cost and unit cos
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● The 14 countries not included i
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on public health by an external Exp
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evised as a result of the introduct
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TABLE 6.2 Incorporation of WHO poli
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FIGURE 6.3The Supranational Referen
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of TB disease by 65%, irrespective
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FIGURE 7.3Percentage of TB patients
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BOX 7.1Accelerating progress in pro
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TABLE 7.2 Assumptions used to estim
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FIGURE 8.1 The development pipeline
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sputum specimens and TB isolates fr
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cal trial sites and building labora
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new TB vaccine candidate. A Phase I
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This annex explains the methods tha
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2011. On average, 15 data points we
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may suffer from biases. These biase
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TABLE A1.3Parameter estimates used
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5. Estimates of TB prevalence, 1990
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the Republic of Moldova, Romania, t
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AFGHANISTANPopulation 2011 32 milli
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BRAZILPopulation 2011 197 millionHI
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CHINAPopulation 2011 1 348 millionH
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ETHIOPIAPopulation 2011 85 millionH
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INDONESIAPopulation 2011 242 millio
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MOZAMBIQUEPopulation 2011 24 millio
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NIGERIAPopulation 2011 162 millionH
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PHILIPPINESPopulation 2011 95 milli
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SOUTH AFRICAPopulation 2011 50 mill
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UGANDAPopulation 2011 35 millionHIG
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VIET NAMPopulation 2011 89 millionH
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ANNEX 3Regional profiles
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WHO REGION OF THE AMERICASPopulatio
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WHO EUROPEAN REGIONPopulation 2011
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WHO WESTERN PACIFIC REGIONPopulatio
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SUMMARY BY WHO REGIONTable A4.1 Est
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MORTALITY (EXCLUDING HIV) PREVALENC
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NEW AND RELAPSENOTIFICATION RATE aY
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-% OF TB PATIENTS WITHKNOWN HIV STA
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AFRICAN REGIONTable A4.1 Estimates
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INCIDENCE (INCLUDING HIV) INCIDENCE
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NEW AND RELAPSENOTIFICATION RATE aY
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NEW AND RELAPSENOTIFICATION RATE a1
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TREATMENT SUCCESS (%) a1995-2010YEA
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-% OF TB PATIENTS WITHKNOWN HIV STA
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YEARTOTALCONFIRMEDCASES OFMDR-TB aE
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MALEYEAR 0-14 15-24 25-34 35-44 45-
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REGION OF THE AMERICASTable A4.1 Es
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INCIDENCE (INCLUDING HIV) INCIDENCE
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% OF COHORTTREATMENT SUCCESS (%) a1
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% OF COHORTTREATMENT SUCCESS (%) a1
Page 196 and 197: % OF COHORTTREATMENT SUCCESS (%) a1
Page 198 and 199: -% OF TB PATIENTS WITHKNOWN HIV STA
Page 200 and 201: YEARTOTALCONFIRMEDCASES OFMDR-TB aE
Page 202 and 203: MALEFEMALEYEAR 0-14 15-24 25-34 35-
Page 204 and 205: EASTERN MEDITERRANEAN REGIONTable A
Page 206 and 207: MORTALITY (EXCLUDING HIV) PREVALENC
Page 208 and 209: INCIDENCE (INCLUDING HIV) INCIDENCE
Page 210 and 211: NEW AND RELAPSENOTIFICATION RATE a1
Page 220 and 221: EUROPEAN REGIONTable A4.1 Estimates
Page 248 and 249: SOUTH-EAST ASIA REGIONTable A4.1 Es
Page 258: SMEAR LABS % OF SMEARPER 100K LABS
Page 261 and 262: Estimates of mortality, prevalence
Page 263 and 264: YEARPOPULATION(MILLIONS)MORTALITY (
Page 265 and 266: YEARPOPULATION(MILLIONS)INCIDENCE (
Page 267 and 268: YEARPOPULATION(MILLIONS)INCIDENCE (
Page 271 and 272: TREATMENT SUCCESS (%) a1995-2010YEA
Page 273 and 274: TREATMENT SUCCESS (%) a1995-2010YEA
Page 281 and 282: SMEAR LABS % OF SMEARPER 100K LABS
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