Global Tuberculosis Report -- 2012.pdf

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NEW AND RELAPSENOTIFICATION RATE a1990–2011YEARNEW ANDRELAPSENEW CASESSMEAR- SMEAR-NEGATIVE/POSITIVE UNKNOWNEXTRA-RE-TREAT EXCL.OTHER RELAPSEPULMONARY RELAPSETOTALRETREATHISTORYUNKNOWN% SMEAR-POS AMONGNEW PULMMalta 1990 13 –1995 11 5 4 2 0 0 562000 16 5 9 2 0 0 0 362005 21 5 10 6 0 1 1 1 332009 41 12 11 6 12 2 2 1 522010 20 4 6 10 0 0 3 3 9 40• 4 5 • 2011 22 7 8 7 0 0 3 3 8 47Monaco 1990 1 –1995 1 –2000 0 0 0 0 0 0 02005 –2009 –2010 1 1 –• 3 0 • 2011 –Montenegro 2005 156 64 66 13 13 14 27 492009 113 53 43 12 0 5 6 11 1 552010 110 39 49 14 0 8 4 12 0 4417 • 2011 110 48 40 12 0 10 2 12 0 55Netherlands 1990 1 369 –1995 1 619 575 1 522 513 272000 1 244 289 528 427 0 70 70 352005 1 127 237 491 385 14 30 44 332009 1 111 203 392 499 17 29 46 20 342010 1 029 176 370 463 4 16 27 43 17 32• 9 6 • 2011 970 177 353 425 3 12 26 38 11 33Norway 1990 285 –1995 236 62 57 89 28 28 522000 221 37 103 79 2 10 12 262005 269 48 119 102 0 14 14 7 292009 258 42 125 37 54 105 252010 274 49 110 115 0 42 42 23 31• 7 0 • 2011 –Poland 1990 16 136 –1995 15 958 6 955 7 285 647 1 071 1 071 492000 10 931 3 180 6 392 477 882 0 882 332005 8 203 2 823 4 591 789 0 1 077 1 077 382009 7 645 2 658 4 047 408 155 377 311 688 280 402010 7 002 2 484 3 625 501 0 392 507 899 0 41• 42 21 • 2011 7 946 2 587 4 344 584 0 431 532 963 0 37Portugal 1990 6 214 –1995 5 577 2 019 1 531 1 759 268 268 572000 4 227 1 863 1 005 1 178 177 304 481 652005 3 303 1 302 974 905 122 228 350 5 572009 2 723 1 043 826 405 326 123 148 271 562010 2 487 912 791 679 16 89 139 228 0 54• 63 0 • 2011 –Republic of 1990 1 728 –Moldova 1995 2 925 665 1 958 154 148 148 252000 2 935 651 1 788 122 374 0 374 272005 5 141 1 696 2 237 568 640 1 137 1 777 432009 4 347 1 318 2 015 471 0 543 1 120 1 663 124 402010 4 122 1 267 2 073 405 0 377 1 312 1 689 13 38• 40 119 • 2011 4 208 1 272 2 140 424 0 372 1 108 1 480 25 37Romania 1990 16 256 –1995 23 271 10 469 8 303 3 422 1 077 1 077 562000 27 470 10 202 10 180 3 474 3 614 156 3 770 502005 26 104 10 801 8 038 3 568 3 697 3 241 6 938 2 572009 20 868 8 987 5 681 2 486 712 3 002 2 399 5 401 612010 18 379 7 951 5 113 2 899 0 2 416 2 699 5 115 0 61• 70 79 • 2011 16 866 7 362 4 557 2 634 0 2 313 2 352 4 665 0 62Russian 1990 50 641 –Federation 1995 84 980 37 512 42 241 5 227 472000 140 677 27 467 102 228 5 313 5 669 12 478 18 147 212005 127 930 32 605 74 301 12 320 8 704 26 449 35 153 302009 126 227 33 351 72 931 10 945 0 9 000 23 569 32 569 6 426 312010 118 641 31 416 67 894 3 513 7 081 8 737 37 243 45 980 6 669 32• 34 79 • 2011 112 910 29 191 65 106 10 023 8 590 46 569 55 159 31San Marino 1990 1 –1995 2 –2000 1 1 0 0 0 0 0 1002005 –2009 –2010 –• 4 0 • 2011 –Serbia 2005 3 208 1 105 1 584 479 40 260 300 0 412009 1 879 1 055 488 197 0 139 64 203 652 682010 2 326 977 700 501 0 148 52 200 7 5822 • 2011 2 171 905 745 401 0 120 42 162 3 55Serbia (without Kosovo) 2005 2 146 873 714 245 552009 1 625 801 5 1002010 1 442 690 431 202 119 119 622011 1 296 654 372 155 91 91 64Kosovo 2005 1 062 232 596 234 282009 254 254 647 1002010 884 287 269 299 29 29 522011 875 251 349 246 29 29 42Serbia & 1990 4 194 –Montenegro 1995 2 798 1 497 930 173 198 198 62• 41 2000 2 864 0 2 486 175 203 0 203 0Slovakia 1990 1 448 –1995 1 540 788 555 177 20 20 592000 1 010 236 469 203 102 18 120 332005 710 162 356 134 58 50 108 312009 438 121 202 61 22 32 47 79 21 372010 386 112 190 59 0 25 30 55 23 37• 27 6 • 2011 352 96 170 57 0 29 21 50 26 36Slovenia 1990 722 –1995 525 303 83 109 30 30 782000 368 145 133 59 31 16 47 522005 269 109 110 30 20 9 29 502009 186 85 70 13 12 6 2 8 552010 169 64 67 30 0 8 3 11 0 49• 37 9 • 2011 181 82 73 26 0 11 11 0 53EUROPEAN REGIONaRates are per 100 000 population.GLOBAL TUBERCULOSIS REPORT 2012 Data can be downloaded from www.who.int/tb/data 223
NEW AND RELAPSENOTIFICATION RATE a1990–2011YEARNEW ANDRELAPSENEW CASESSMEAR- SMEAR-NEGATIVE/POSITIVE UNKNOWNEXTRA-RE-TREAT EXCL.OTHER RELAPSEPULMONARY RELAPSETOTALRETREATHISTORYUNKNOWN% SMEAR-POS AMONGNEW PULMSpain 1990 7 600 –1995 8 764 2 605 6 159 302000 7 993 3 423 4 446 124 0 0 0 432005 7 281 2 511 3 880 890 0 1 078 1 078 392009 6 687 2 236 2 879 1 572 905 442010 6 377 2 076 2 621 1 680 0 0 324 324 388 44• 20 13 • 2011 6 044 2 186 2 242 1 616 0 0 370 370 348 49Sweden 1990 557 –1995 564 102 235 216 11 11 302000 417 118 147 152 0 40 40 452005 539 134 208 197 0 30 30 392009 515 107 180 228 112 372010 552 117 226 209 0 0 52 52 71 34• 7 5 • 2011 457 99 182 173 0 3 42 45 87 35Switzerland 1990 1 278 –1995 830 185 515 126 5 5 262000 404 86 216 102 63 63 173 282005 381 84 187 110 49 49 133 312009 334 74 163 97 51 51 169 312010 322 82 149 91 40 40 186 35• 19 5 • 2011 379 90 170 119 54 54 145 35Tajikistan 1990 2 460 –1995 2 029 1 042 617 370 370 632000 2 779 434 1 918 427 182005 5 460 1 745 2 175 1 417 123 2 066 2 189 452009 6 125 1 972 2 208 1 684 261 272 533 1 085 472010 6 297 2 290 2 038 1 631 0 338 647 985 697 53• 46 90 • 2011 6 290 2 174 2 148 1 613 0 355 574 929 745 50The Former 1990 –Yugoslav Republic 1995 786 319 376 66 25 25 46of Macedonia 2000 641 167 308 150 16 0 16 352005 598 178 236 141 43 60 103 432009 450 198 103 116 0 33 23 56 0 662010 384 141 135 92 0 16 36 52 0 51• 0 16 • 2011 335 132 99 76 0 28 27 55 0 57Turkey 1990 24 468 –1995 22 981 4 383 17 534 1 064 202000 18 038 4 315 8 544 4 371 808 808 342005 19 744 7 450 5 944 5 359 991 1 559 2 550 562009 16 757 6 007 4 289 5 647 0 814 631 1 445 14 582010 15 879 5 375 4 191 5 617 0 696 672 1 368 0 56• 45 20 • 2011 15 054 4 927 3 925 5 565 0 637 625 1 262 0 56Turkmenistan 1990 2 325 –1995 1 939 544 1 327 1 67 67 292000 4 038 1 017 2 709 241 71 1 894 1 965 272005 3 191 995 1 498 656 42 100 142 402009 3 157 1 370 1 223 564 532010 3 230 1 153 1 248 473 274 82 82 48• 63 0 • 2011 –Ukraine 1990 16 465 –1995 21 459 8 263 9 793 1 514 1 889 1 889 462000 32 945 10 738 17 258 1 739 3 210 0 3 210 382005 39 608 –2009 36 075 13 632 15 934 3 858 2 651 2 826 5 477 462010 33 857 9 976 17 599 3 355 365 2 562 2 552 5 114 36• 32 76 • 2011 34 237 10 502 14 106 3 367 3 213 3 049 7 858 10 907 581 43United Kingdom of 1990 5 908 –Great Britain and 1995 6 176 4 162 2 014 –Northern Ireland 2000 6 220 1 204 2 037 2 478 0 0 0 372005 8 173 1 821 2 752 3 600 0 460 460 402009 7 008 1 256 2 462 3 262 28 2 032 342010 7 219 1 201 2 551 3 443 24 576 576 688 32• 10 13 • 2011 7 850 1 204 2 827 3 783 36 524 524 589 30Uzbekistan 1990 9 414 –1995 9 866 2 735 5 798 1 333 322000 15 750 3 825 10 142 1 760 23 324 347 272005 21 513 5 695 7 857 6 324 1 637 7 378 9 015 422009 17 540 4 959 6 943 4 667 971 1 480 2 451 2 433 422010 16 883 4 711 6 735 4 288 0 1 149 3 447 4 596 0 41• 46 52 • 2011 14 501 4 198 5 958 3 839 0 506 568 1 074 844 41aRates are per 100 000 population.224 Data can be downloaded from www.who.int/tb/data GLOBAL TUBERCULOSIS REPORT 2012
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GLOBALTUBERCULOSISREPORT2012
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ContentsAbbreviationsivAcknowledgem
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AcknowledgementsThis report on glob
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WHO Western Pacific RegionShalala A
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Executive SummaryThe World Health O
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CHAPTER 1IntroductionBOX 1.1Basic f
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TABLE 1.1 Targets for the scale-up
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TABLE 1.2 Reporting of data in the
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BOX 2.1Uncertainty in estimates of
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TABLE 2.2 Estimated burden of disea
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FIGURE 2.5 Estimated TB incidence r
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FIGURE B2.2.1Reporting of notificat
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FIGURE 2.8Estimated TB incidence ra
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FIGURE 2.11 Countries (in blue) for
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FIGURE 2.12 Trends in estimated TB
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● producing and widely disseminat
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FIGURE 2.16 Progress in global cove
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BOX 2.6Efforts by the Task Force to
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CHAPTER 3TB case notificationsand t
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BOX 3.1 1Definitions of TB casesDef
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TABLE 3.3 Contribution of public-pr
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BOX 3.4Integrating community-based
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TABLE 3.4 Estimates of the case det
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TABLE 3.5 Treatment success for new
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CHAPTER 4Drug-resistant TBKEY FACTS
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FIGURE 4.2 Percentage of new TB cas
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BOX 4.1Frequencies of resistance to
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FIGURE 4.6 Number of MDR-TB cases e
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FIGURE 4.7Notified cases of MDR-TB
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egimens globally, providing more su
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5.1 Funding for TB care and control
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TABLE 5.2 NTP budgets, available fu
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FIGURE 5.5Trends in domestic and do
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FIGURE 5.6Domestic funding as a per
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FIGURE 5.8Cost per TB patient succe
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FIGURE 5.10 Total cost and unit cos
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● The 14 countries not included i
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on public health by an external Exp
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evised as a result of the introduct
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TABLE 6.2 Incorporation of WHO poli
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FIGURE 6.3The Supranational Referen
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of TB disease by 65%, irrespective
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FIGURE 7.3Percentage of TB patients
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BOX 7.1Accelerating progress in pro
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TABLE 7.2 Assumptions used to estim
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FIGURE 8.1 The development pipeline
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sputum specimens and TB isolates fr
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cal trial sites and building labora
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new TB vaccine candidate. A Phase I
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This annex explains the methods tha
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2011. On average, 15 data points we
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may suffer from biases. These biase
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TABLE A1.3Parameter estimates used
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5. Estimates of TB prevalence, 1990
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the Republic of Moldova, Romania, t
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AFGHANISTANPopulation 2011 32 milli
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BRAZILPopulation 2011 197 millionHI
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CHINAPopulation 2011 1 348 millionH
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ETHIOPIAPopulation 2011 85 millionH
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INDONESIAPopulation 2011 242 millio
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MOZAMBIQUEPopulation 2011 24 millio
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NIGERIAPopulation 2011 162 millionH
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PHILIPPINESPopulation 2011 95 milli
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SOUTH AFRICAPopulation 2011 50 mill
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UGANDAPopulation 2011 35 millionHIG
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VIET NAMPopulation 2011 89 millionH
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ANNEX 3Regional profiles
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WHO REGION OF THE AMERICASPopulatio
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WHO EUROPEAN REGIONPopulation 2011
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WHO WESTERN PACIFIC REGIONPopulatio
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SUMMARY BY WHO REGIONTable A4.1 Est
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MORTALITY (EXCLUDING HIV) PREVALENC
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NEW AND RELAPSENOTIFICATION RATE aY
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-% OF TB PATIENTS WITHKNOWN HIV STA
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AFRICAN REGIONTable A4.1 Estimates
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INCIDENCE (INCLUDING HIV) INCIDENCE
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NEW AND RELAPSENOTIFICATION RATE aY
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NEW AND RELAPSENOTIFICATION RATE a1
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TREATMENT SUCCESS (%) a1995-2010YEA
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-% OF TB PATIENTS WITHKNOWN HIV STA
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YEARTOTALCONFIRMEDCASES OFMDR-TB aE
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MALEYEAR 0-14 15-24 25-34 35-44 45-
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REGION OF THE AMERICASTable A4.1 Es
Page 182 and 183: MORTALITY (EXCLUDING HIV) PREVALENC
Page 186 and 187: INCIDENCE (INCLUDING HIV) INCIDENCE
Page 188 and 189: NEW AND RELAPSENOTIFICATION RATE a1
Page 192 and 193: % OF COHORTTREATMENT SUCCESS (%) a1
Page 198 and 199: -% OF TB PATIENTS WITHKNOWN HIV STA
Page 200 and 201: YEARTOTALCONFIRMEDCASES OFMDR-TB aE
Page 202 and 203: MALEFEMALEYEAR 0-14 15-24 25-34 35-
Page 204 and 205: EASTERN MEDITERRANEAN REGIONTable A
Page 220 and 221: EUROPEAN REGIONTable A4.1 Estimates
Page 248 and 249: SOUTH-EAST ASIA REGIONTable A4.1 Es
Page 258: SMEAR LABS % OF SMEARPER 100K LABS
Page 261 and 262: Estimates of mortality, prevalence
Page 263 and 264: YEARPOPULATION(MILLIONS)MORTALITY (
Page 265 and 266: YEARPOPULATION(MILLIONS)INCIDENCE (
Page 267 and 268: YEARPOPULATION(MILLIONS)INCIDENCE (
Page 271 and 272: TREATMENT SUCCESS (%) a1995-2010YEA
Page 273 and 274: TREATMENT SUCCESS (%) a1995-2010YEA
Page 281 and 282: SMEAR LABS % OF SMEARPER 100K LABS
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