Global Tuberculosis Report -- 2012.pdf

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MALEFEMALEYEAR 0–14 15–24 25–34 35–44 45–54 55–64 65+0–14 15–24 25–34 35–44 45–54 55–64 65+UN-KNOWNUN-KNOWNMALE:FEMALERATIONiue 1995 –2000 –2005 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –2010 –2011 –Northern Mariana 1995 1 1 3 5 10 3 3 0 0 2 6 4 1 1 1.9Islands 2000 1 4 8 9 9 3 2 0 10 17 7 3 1 1 0.922005 0 0 1 3 4 1 2 0 0 0 1 1 1 1 2.82010 0 2 0 0 3 3 0 0 0 2 0 1 3 2 1 0 0.892011 0 0 0 0 1 5 3 0 0 0 1 0 2 3 0 0 1.5Palau 1995 0 2 3 0 2 1 0 0 0 0 0 1 0 0 8.02000 –2005 2 1 –2010 0 1 2 1 1 1 1 0 1 0 1 1 0 0 0 0 2.32011 0 0 0 1 0 2 0 0 0 0 1 0 0 0 0 0 3.0Papua New 1995 –Guinea 2000 8 87 70 30 21 12 5 6 77 45 21 15 5 1 1.42005 28 183 205 108 94 48 12 38 200 204 124 65 35 2 1.02010 37 279 260 196 135 87 27 64 313 292 191 97 52 9 1.02011 50 278 265 152 122 71 18 53 302 272 146 97 55 15 1.0Philippines 1995 2 43 56 61 46 47 26 1 20 32 26 20 19 11 2.22000 –2005 482 7 358 11 275 13 253 12 531 7 646 4 279 374 3 710 5 268 5 565 4 603 3 274 2 029 2.32010 511 9 320 12 224 13 716 13 651 8 923 4 742 0 454 4 825 5 489 5 301 4 643 3 329 2 070 0 2.42011 573 9 725 12 804 14 474 14 002 9 568 4 845 448 5 155 5 848 5 521 4 880 3 501 2 236 2.4Republic of Korea 1995 27 1 131 1 613 1 425 1 207 1 307 1 225 46 908 863 431 296 408 867 2.12000 19 821 1 085 988 853 731 901 25 546 544 393 220 295 795 1.92005 22 687 1 171 1 326 1 336 1 005 1 669 27 590 842 491 370 373 1 729 1.62010 22 537 705 1 049 1 496 1 029 1 997 0 23 472 686 509 487 368 2 216 0 1.42011 13 491 712 1 019 1 414 1 145 2 132 0 37 446 688 520 432 421 2 244 0 1.4Samoa 1995 0 1 1 1 0 3 2 1 2 2 0 0 1 1 1.12000 0 3 1 1 1 2 1 0 2 1 1 0 0 0 2.22005 0 4 0 1 1 0 0 0 2 0 2 0 1 0 1.22010 1 1 1 3 2 1 3 1.02011 0 1 0 0 0 0 0 0 0 2 1 0 1 0 1 0 0.20Singapore 1995 0 9 40 60 62 70 94 1 8 18 21 22 19 31 2.82000 1 8 9 34 51 26 64 1 9 8 7 9 5 16 3.52005 0 8 25 61 94 96 118 0 5 20 33 29 20 43 2.72010 0 11 21 38 105 86 120 0 1 15 21 26 21 21 44 0 2.62011 0 21 21 44 108 119 126 0 0 11 25 23 23 20 51 0 2.9Solomon Islands 1995 2 14 6 5 7 9 3 3 17 11 7 12 13 0 0.732000 3 13 4 8 8 10 6 8 15 13 7 7 5 2 0.912005 4 14 18 9 15 12 11 9 23 21 12 11 9 1 0.972010 4 16 18 16 8 3 3 0 4 19 17 11 5 4 5 0 1.02011 3 15 22 12 7 8 6 0 3 13 27 15 10 16 2 0 0.85Tokelau 1995 –2000 –2005 –2010 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –2011 –Tonga 1995 0 1 0 0 0 1 2 0 0 1 1 0 2 1 0.802000 2 1 1 1 5 1 1 1 1 1 2.02005 0 2 1 0 2 1 0 0 2 1 0 0 2 0 1.22010 0 0 0 1 0 1 3 0 0 0 0 0 1 0 0 0 5.02011 0 0 1 0 0 0 1 0 2 0 1 1 0 0 0 0 0.50Tuvalu 1995 1 0 1 0 0 1 0 0 1 1 0 0 1 0 1.02000 –2005 1 1 1 2 0.672010 0 1 0 0 1 2 0 0 0 1 0 0 0 0 4.02011 1 1 1 1 3.0Vanuatu 1995 0 6 2 5 3 4 0 0 5 0 2 3 0 0 2.02000 2 7 5 1 10 5 2 5 3 15 7 3 3 1 0.862005 1 4 5 5 0 4 1 0 5 1 2 4 1 2 1.32010 4 6 3 1 5 2 0 0 3 5 3 3 5 3 1 0 0.912011 2 3 4 6 5 4 2 0 0 5 7 5 4 2 0 0 1.1Viet Nam 1995 –2000 51 2 367 6 147 8 209 6 713 5 150 7 712 64 1 334 2 320 2 754 2 594 2 847 4 907 2.22005 54 3 408 7 105 8 738 8 606 4 958 7 573 47 1 747 2 293 2 116 2 298 2 023 4 604 2.72010 59 3 205 7 036 7 851 8 564 5 790 6 248 0 53 1 870 2 454 1 681 1 864 1 863 3 751 0 2.92011 61 3 099 6 677 7 763 8 474 6 107 5 821 0 64 1 863 2 325 1 681 1 814 1 878 3 124 0 3.0Wallis and Futuna 1995 –Islands 2000 –2005 –2010 –2011 2 –WESTERN PACIFIC REGIONGLOBAL TUBERCULOSIS REPORT 2012 Data can be downloaded from www.who.int/tb/data 271
SMEAR LABS % OF SMEARPER 100K LABS USINGPOPULATION LED aCULTURELABS PER 5MPOPULATIONLABORATORIESDST b LABSPER 5MPOPULATIONLPA c LABSPER 5MPOPULATIONNUMBER OFLABS USINGXPERT MTB/RIFSECOND-LINE DSTAVAILABLENRL dFREE THROUGH NTPTB DIAGNOSISFIRST-LINEDRUGSTB NOTIF.RIFAMPICINRATE PERUSED100 000THROUGHOUTHEALTH-CARETREATMENTWORKERSAmerican Samoa – No No Yes (all suspects) yes YesAustralia – In country yes Yes (all suspects) yes YesBrunei Darussalam 0.2 0 12.3 12.3 12.3 0 yes Yes (all suspects) yes Yes 56Cambodia 1.5 9 1.0 0.3 0 1Out ofcountryyes Yes (all suspects) yes YesChina 0.2 2 2.2 0.7
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GLOBALTUBERCULOSISREPORT2012
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ContentsAbbreviationsivAcknowledgem
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AcknowledgementsThis report on glob
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WHO Western Pacific RegionShalala A
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Executive SummaryThe World Health O
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CHAPTER 1IntroductionBOX 1.1Basic f
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TABLE 1.1 Targets for the scale-up
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TABLE 1.2 Reporting of data in the
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BOX 2.1Uncertainty in estimates of
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TABLE 2.2 Estimated burden of disea
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FIGURE 2.5 Estimated TB incidence r
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FIGURE B2.2.1Reporting of notificat
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FIGURE 2.8Estimated TB incidence ra
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FIGURE 2.11 Countries (in blue) for
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FIGURE 2.12 Trends in estimated TB
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● producing and widely disseminat
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FIGURE 2.16 Progress in global cove
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BOX 2.6Efforts by the Task Force to
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CHAPTER 3TB case notificationsand t
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BOX 3.1 1Definitions of TB casesDef
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TABLE 3.3 Contribution of public-pr
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BOX 3.4Integrating community-based
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TABLE 3.4 Estimates of the case det
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TABLE 3.5 Treatment success for new
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CHAPTER 4Drug-resistant TBKEY FACTS
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FIGURE 4.2 Percentage of new TB cas
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BOX 4.1Frequencies of resistance to
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FIGURE 4.6 Number of MDR-TB cases e
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FIGURE 4.7Notified cases of MDR-TB
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egimens globally, providing more su
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5.1 Funding for TB care and control
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TABLE 5.2 NTP budgets, available fu
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FIGURE 5.5Trends in domestic and do
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FIGURE 5.6Domestic funding as a per
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FIGURE 5.8Cost per TB patient succe
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FIGURE 5.10 Total cost and unit cos
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● The 14 countries not included i
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on public health by an external Exp
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evised as a result of the introduct
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TABLE 6.2 Incorporation of WHO poli
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FIGURE 6.3The Supranational Referen
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of TB disease by 65%, irrespective
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FIGURE 7.3Percentage of TB patients
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BOX 7.1Accelerating progress in pro
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TABLE 7.2 Assumptions used to estim
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FIGURE 8.1 The development pipeline
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sputum specimens and TB isolates fr
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cal trial sites and building labora
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new TB vaccine candidate. A Phase I
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This annex explains the methods tha
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2011. On average, 15 data points we
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may suffer from biases. These biase
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TABLE A1.3Parameter estimates used
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5. Estimates of TB prevalence, 1990
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the Republic of Moldova, Romania, t
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AFGHANISTANPopulation 2011 32 milli
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BRAZILPopulation 2011 197 millionHI
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CHINAPopulation 2011 1 348 millionH
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ETHIOPIAPopulation 2011 85 millionH
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INDONESIAPopulation 2011 242 millio
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MOZAMBIQUEPopulation 2011 24 millio
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NIGERIAPopulation 2011 162 millionH
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PHILIPPINESPopulation 2011 95 milli
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SOUTH AFRICAPopulation 2011 50 mill
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UGANDAPopulation 2011 35 millionHIG
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VIET NAMPopulation 2011 89 millionH
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ANNEX 3Regional profiles
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WHO REGION OF THE AMERICASPopulatio
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WHO EUROPEAN REGIONPopulation 2011
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WHO WESTERN PACIFIC REGIONPopulatio
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SUMMARY BY WHO REGIONTable A4.1 Est
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MORTALITY (EXCLUDING HIV) PREVALENC
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NEW AND RELAPSENOTIFICATION RATE aY
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-% OF TB PATIENTS WITHKNOWN HIV STA
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AFRICAN REGIONTable A4.1 Estimates
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INCIDENCE (INCLUDING HIV) INCIDENCE
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NEW AND RELAPSENOTIFICATION RATE aY
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NEW AND RELAPSENOTIFICATION RATE a1
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TREATMENT SUCCESS (%) a1995-2010YEA
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YEARTOTALCONFIRMEDCASES OFMDR-TB aE
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MALEYEAR 0-14 15-24 25-34 35-44 45-
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REGION OF THE AMERICASTable A4.1 Es
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% OF COHORTTREATMENT SUCCESS (%) a1
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YEARTOTALCONFIRMEDCASES OFMDR-TB aE
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MALEFEMALEYEAR 0-14 15-24 25-34 35-
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EASTERN MEDITERRANEAN REGIONTable A
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MALEFEMALEYEAR 0-14 15-24 25-34 35-
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EUROPEAN REGIONTable A4.1 Estimates
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Page 230 and 231: NEW AND RELAPSENOTIFICATION RATE a1
Page 234 and 235: % OF COHORTTREATMENT SUCCESS (%) a1
Page 240 and 241: -% OF TB PATIENTS WITHKNOWN HIV STA
Page 242 and 243: YEARTOTALCONFIRMEDCASES OFMDR-TB aE
Page 244 and 245: MALEFEMALEYEAR 0-14 15-24 25-34 35-
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Page 248 and 249: SOUTH-EAST ASIA REGIONTable A4.1 Es
Page 250 and 251: MORTALITY (EXCLUDING HIV) PREVALENC
Page 258: SMEAR LABS % OF SMEARPER 100K LABS
Page 261 and 262: Estimates of mortality, prevalence
Page 263 and 264: YEARPOPULATION(MILLIONS)MORTALITY (
Page 265 and 266: YEARPOPULATION(MILLIONS)INCIDENCE (
Page 267 and 268: YEARPOPULATION(MILLIONS)INCIDENCE (
Page 271 and 272: TREATMENT SUCCESS (%) a1995-2010YEA
Page 273 and 274: TREATMENT SUCCESS (%) a1995-2010YEA
Page 275 and 276: -% OF TB PATIENTS WITHKNOWN HIV STA
Page 279: MALEFEMALEYEAR 0-14 15-24 25-34 35-
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