Global Tuberculosis Report -- 2012.pdf

FIGURE 3.3Case notification and estimated TB incidence rates, 22 high-burden countries, 1990–2011. Trends in casenotifi cation rates (new and relapse cases, all forms) (black) and estimated TB incidence rates (green). Shaded areasrepresent uncertainty bands.Afghanistan Bangladesh BrazilCambodiaChina3002001003002001001005080060040020020015010050Rate per 100 000 population per year040030020010001200100080060040020001501005003002502001501005001990 1995 2000 2005 2011 1990 1995 2000 2005 20110000DR Congo Ethiopia India8002506002004001501002005000Mozambique Myanmar NigeriaPakistanPhilippines6005006006003004004004003002002002001002001000000Russian Federation South Africa ThailandUgandaUR Tanzania250120030010005000Viet NamZimbabwe10008006004002000IndonesiaKenya3002504002003001502001005010000200100025015080020060015010040010050200500001990 1995 2000 2005 2011 1990 1995 2000 2005 2011 1990 1995 2000 2005 2011BOX 3.5Definitions of treatment outcomes for drug-susceptible TBCured A patient who was initially sputum smear-positive and who was sputum smear-negative in the last month of treatment and on atleast one previous occasion.Completed treatment A patient who completed treatment but did not meet the criteria for cure or failure. This defi nition applies tosputum smear-positive and sputum smear-negative patients with pulmonary TB and to patients with extrapulmonary disease.Died A patient who died from any cause during treatment.Failed A patient who was initially sputum smear-positive and who remained sputum smear-positive at month 5 or later during treatment.Defaulted A patient whose treatment was interrupted for 2 consecutive months or more.Not evaluated A patient whose treatment outcome is not known.Successfully treated A patient who was cured or who completed treatment.Cohort A group of patients in whom TB has been diagnosed, and who were registered for treatment during a specifi ed time period (e.g.the cohort of new sputum smear-positive cases registered in the calendar year 2010). This group forms the denominator for calculatingtreatment outcomes. The sum of the above treatment outcomes, plus any cases for whom no outcome is recorded (including those “stillon treatment” in the European Region) and “transferred out” cases should equal the number of cases registered. Some countries monitoroutcomes among cohorts defi ned by sputum smear and/or culture, and defi ne cure and failure according to the best laboratory evidenceavailable for each patient.38 GLOBAL TUBERCULOSIS REPORT 2012