Global Tuberculosis Report -- 2012.pdf

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MALEFEMALEYEAR 0–14 15–24 25–34 35–44 45–54 55–64 65+0–14 15–24 25–34 35–44 45–54 55–64 65+UN-KNOWNUN-KNOWNMALE:FEMALERATIOAlbania 1995 0 0 0 0 19 40 30 0 1 0 0 13 20 16 1.82000 2 19 21 14 24 19 16 3 11 10 8 8 5 11 2.12005 0 26 21 16 31 20 37 0 0 3 9 5 5 5 18 0 3.42010 0 28 17 14 16 16 15 0 2 11 7 6 3 2 8 0 2.72011 0 29 26 18 30 9 22 0 1 14 10 6 2 1 12 0 2.9Andorra 1995 –2000 0 0 1 0 0 0 0 –2005 0 0 1 1 0 0 0 0 0 1 1 1 0 0 0 0 0.672010 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –2011 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 –Armenia 1995 1 18 16 11 10 8 1 1 1 7 2 1 1 5.02000 2 152 130 131 63 26 21 1 24 27 24 8 8 4 5.52005 3 170 104 83 84 30 24 0 3 27 21 10 11 4 7 0 6.02010 0 36 75 49 68 27 15 0 1 24 17 4 7 8 8 0 3.92011 0 28 65 52 71 42 8 0 0 19 16 9 7 7 5 0 4.2Austria 1995 4 37 95 82 89 71 73 6 22 52 32 21 18 59 2.12000 1 17 30 59 42 23 41 1 11 22 12 11 6 22 2.52005 1 32 23 22 41 24 30 0 0 13 11 8 3 5 10 0 3.52010 0 4 4 12 13 8 10 0 1 5 4 2 2 5 6 0 2.02011 0 8 11 9 13 11 13 0 0 11 6 4 1 3 4 0 2.2Azerbaijan 1995 0 13 29 14 6 4 1 0 5 18 0 0 0 0 2.92000 0 9 24 33 42 30 0 0 3 3 6 3 0 0 9.22005 77 109 297 215 209 187 88 0 90 64 98 47 32 24 24 0 3.12010 0 328 371 267 280 30 27 3 141 100 57 73 9 18 3.22011 –Belarus 1995 –2000 –2005 71 180 273 287 118 62 25 53 50 43 11 62 4.12010 0 65 173 224 293 163 58 0 1 28 52 56 37 28 91 0 3.32011 1 53 156 228 290 138 48 3 37 67 47 39 27 83 3.0Belgium 1995 3 23 49 63 52 54 102 3 12 24 32 17 10 34 2.62000 3 20 57 39 55 32 56 6 15 15 19 4 13 27 2.62005 1 26 50 32 27 15 47 0 2 27 31 15 12 4 23 0 1.72010 4 20 39 30 29 21 19 0 6 13 18 19 11 5 10 0 2.02011 –Bosnia and 1995 0 15 61 90 140 139 100 0 40 67 64 49 77 23 1.7Herzegovina 2000 4 56 82 99 66 58 77 4 30 46 29 29 48 124 1.42005 1 22 58 61 78 44 80 1 2 35 39 33 28 28 130 0 1.22010 1 27 37 34 61 46 51 0 0 27 19 16 10 18 94 0 1.42011 2 33 32 52 75 61 62 0 3 17 27 17 13 25 128 0 1.4Bulgaria 1995 –2000 0 13 16 20 3 9 10 0 11 14 7 3 4 6 1.62005 9 98 150 195 195 150 136 0 9 90 111 59 29 37 70 0 2.32010 1 40 115 143 133 90 65 0 3 42 59 43 23 15 34 0 2.72011 2 38 100 110 122 92 61 0 2 41 40 36 28 14 30 0 2.7Croatia 1995 6 38 97 210 132 178 141 10 50 57 57 38 60 130 2.02000 –2005 1 24 27 48 72 47 34 0 1 12 18 15 11 6 56 0 2.12010 0 10 19 18 38 25 24 1 3 8 4 2 1 30 2.72011 0 12 5 20 31 31 21 0 0 12 14 14 8 7 26 0 1.5Cyprus 1995 0 1 1 0 1 1 2 0 1 1 1 2 0 1 1.02000 –2005 0 3 1 1 1 0 1 0 0 1 0 0 0 0 0 0 7.02010 0 2 1 0 0 0 0 0 0 0 3 1 0 0 0 1 0.602011 –Czech Republic 1995 2 10 22 83 88 53 90 0 9 11 20 13 19 88 2.22000 0 7 31 52 89 61 59 0 15 13 9 10 7 57 2.72005 0 8 24 57 55 45 46 0 0 3 14 16 7 5 28 0 3.22010 0 12 19 36 29 29 19 0 0 6 10 11 7 2 20 0 2.62011 –Denmark 1995 0 7 16 28 18 9 11 2 7 13 8 4 3 2 2.32000 5 10 20 24 16 11 14 5 16 15 14 6 7 8 1.42005 0 12 12 18 23 9 7 0 2 11 5 13 9 3 5 0 1.72010 0 8 22 10 13 16 2 0 0 4 5 15 8 8 4 0 1.62011 –Estonia 1995 –2000 0 6 31 53 56 35 15 0 9 11 14 11 4 10 3.32005 0 9 25 19 40 12 7 0 0 6 11 8 11 6 8 0 2.22010 0 3 7 21 25 12 8 0 0 3 5 3 3 6 3 0 3.32011 0 4 22 16 14 18 13 0 0 4 8 12 3 3 6 0 2.4Finland 1995 1 1 10 25 28 24 61 1 1 6 7 4 10 65 1.62000 0 3 8 22 19 28 53 0 1 5 3 4 6 49 2.02005 1 5 4 3 14 11 25 0 0 3 4 1 0 6 20 0 1.92010 0 10 6 8 9 8 18 0 0 3 2 4 1 2 11 0 2.62011 0 1 4 4 7 11 27 0 1 2 3 5 3 1 13 0 1.9France 1995 30 156 431 502 414 297 496 36 138 226 176 90 92 365 2.12000 10 136 248 247 211 125 244 18 108 127 89 46 43 155 2.12005 12 127 212 222 196 134 205 0 16 104 134 82 56 38 180 0 1.82010 10 60 139 114 99 76 110 0 10 47 76 49 45 25 97 0 1.72011 –Georgia 1995 2 20 30 25 40 18 12 2 8 17 17 18 7 5 2.02000 4 76 111 113 63 45 28 1 49 37 33 17 10 5 2.92005 0 226 272 268 207 76 60 4 109 105 58 46 17 47 2.92010 5 340 529 341 264 143 77 0 5 135 118 62 52 28 41 0 3.92011 5 271 478 333 251 139 93 0 8 136 132 59 32 35 54 0 3.4Germany 1995 14 179 453 539 460 442 625 17 115 251 167 89 104 397 2.42000 –2005 6 59 113 171 167 92 167 0 4 51 104 73 43 37 103 0 1.92010 1 43 92 97 141 87 136 0 3 44 63 61 38 26 76 0 1.92011 1 43 95 106 141 68 127 0 2 44 90 59 54 26 85 0 1.6Greece 1995 –2000 1 10 22 32 24 19 46 0 2 9 10 5 6 25 2.72005 1 14 25 22 14 12 23 5 0 13 18 8 7 2 17 0 1.82010 1 19 27 20 18 19 22 3 3 2 13 4 4 4 15 1 2.82011 –Greenland 1995 –2000 –2005 –2010 0 5 7 5 5 2 2 0 1 5 0 0 4 2 0 0 2.22011 –Hungary 1995 –2000 0 8 24 85 104 58 27 1 7 17 19 22 10 30 2.92005 0 6 24 67 117 67 39 0 1 5 13 11 22 15 33 0 3.22010 1 9 15 36 51 52 23 0 0 9 16 14 9 15 20 0 2.32011 –EUROPEAN REGIONGLOBAL TUBERCULOSIS REPORT 2012 Data can be downloaded from www.who.int/tb/data 235
MALEFEMALEYEAR 0–14 15–24 25–34 35–44 45–54 55–64 65+0–14 15–24 25–34 35–44 45–54 55–64 65+UN-KNOWNUN-KNOWNMALE:FEMALERATIOIceland 1995 0 0 0 0 0 0 1 0 0 0 0 0 0 1 1.02000 0 1 –2005 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 –2010 0 0 1 0 3 0 0 0 0 0 1 1 0 0 0 0 2.02011 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 –Ireland 1995 –2000 0 10 7 7 6 4 12 0 13 8 13 6 7 15 0.742005 1 6 10 21 10 7 6 0 0 9 10 3 3 0 8 0 1.82010 0 8 18 4 11 5 11 0 0 7 8 2 3 2 5 0 2.12011 0 7 9 10 11 7 8 0 0 8 7 7 8 2 1 0 1.6Israel 1995 –2000 0 20 26 23 23 13 38 0 3 10 16 6 3 3 32 0 2.02005 1 4 15 18 15 5 26 0 0 6 14 7 7 5 19 0 1.42010 1 13 28 12 8 4 6 0 0 1 8 10 2 0 10 0 2.32011 0 29 30 11 5 9 9 0 0 10 10 7 4 4 7 0 2.2Italy 1995 9 59 202 157 94 124 289 7 52 93 57 40 51 168 2.02000 12 63 96 75 58 54 112 6 38 58 33 13 19 39 2.32005 8 93 191 137 101 61 115 24 3 80 145 56 25 19 70 9 1.82010 14 40 75 66 32 31 58 2 25 41 57 41 22 22 54 6 1.22011 13 32 47 50 36 23 58 1 10 31 51 40 17 14 52 1 1.2Kazakhstan 1995 –2000 36 1 057 1 409 1 379 923 439 218 84 999 1 079 599 275 202 204 1.62005 31 917 1 142 983 795 274 175 0 46 751 767 436 286 121 187 0 1.72010 15 675 754 595 511 251 127 0 33 566 520 263 205 122 132 0 1.62011 6 602 716 516 515 235 91 0 15 439 495 260 190 109 117 0 1.6Kyrgyzstan 1995 3 109 171 165 65 38 30 1 70 94 34 18 15 19 2.32000 4 128 227 205 115 52 46 6 128 146 100 41 30 29 1.62005 1 247 303 269 194 66 84 0 15 215 236 141 70 33 98 0 1.42010 5 261 260 188 141 64 48 0 5 223 199 98 71 40 42 0 1.42011 6 225 204 179 168 77 41 0 13 200 191 84 60 50 39 0 1.4Latvia 1995 0 20 44 71 70 40 30 0 22 49 55 47 27 29 1.22000 0 53 106 124 111 64 34 2 25 41 27 28 7 15 3.42005 1 22 71 104 117 55 34 0 0 17 31 31 23 18 12 0 3.12010 0 20 44 65 71 39 15 0 0 6 19 25 12 10 13 0 3.02011 0 11 42 58 50 33 18 0 0 7 16 19 14 12 13 0 2.6Lithuania 1995 4 46 132 225 176 90 77 5 6 53 45 32 16 42 3.82000 1 38 97 145 155 74 68 0 20 37 39 32 22 48 2.92005 0 42 118 186 187 108 67 0 1 25 41 57 49 23 54 0 2.82010 1 34 75 128 157 89 54 0 1 20 36 31 43 18 32 0 3.02011 1 25 52 126 158 77 55 0 0 20 31 37 38 16 45 0 2.6Luxembourg 1995 –2000 –2005 0 0 2 2 1 1 2 0 0 0 2 1 1 1 0 0 1.62010 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –2011 0 1 0 0 1 1 0 0 0 1 0 0 0 0 0 0 3.0Malta 1995 0 0 0 1 0 0 0 0 0 1 0 0 1 2 0.252000 0 1 0 1 1 0 1 –2005 0 1 1 1 1 1 0 0 0 0 0 0 0 0 0 0 –2010 0 0 3 0 0 0 0 0 0 0 1 0 0 0 0 0 3.02011 0 2 4 0 0 0 0 0 0 1 0 0 0 0 0 0 6.0Monaco 1995 –2000 –2005 –2010 –2011 –Montenegro 2005 0 3 5 7 15 4 8 0 0 0 7 3 4 0 8 0 1.92010 0 1 1 4 4 7 1 0 1 3 3 2 3 1 8 0 0.862011 0 1 2 8 11 7 3 0 1 4 2 4 3 1 1 0 2.0Netherlands 1995 22 79 119 75 28 9 10 24 56 50 13 10 8 7 2.02000 0 34 63 41 25 10 21 4 29 22 16 9 5 10 2.02005 0 23 42 23 26 14 19 0 3 14 19 11 9 1 4 0 2.42010 0 22 29 22 20 9 17 0 1 9 14 13 5 4 11 0 2.12011 2 22 35 19 23 14 13 0 2 13 13 7 7 4 3 0 2.6Norway 1995 0 4 8 6 3 5 12 0 4 7 2 0 3 8 1.62000 0 1 9 3 6 2 4 1 3 1 2 5 2.12005 0 9 4 6 4 4 3 0 0 4 7 2 1 0 3 0 1.82010 0 9 9 7 1 4 2 0 0 5 7 3 2 0 0 0 1.92011 –Poland 1995 3 122 295 795 565 369 377 4 129 163 225 111 107 414 2.22000 1 99 303 812 782 361 434 1 99 158 211 170 82 421 2.42005 3 109 199 389 639 292 310 0 3 95 142 112 151 63 316 0 2.22010 3 70 205 310 574 393 237 0 2 59 118 82 104 82 245 0 2.62011 5 69 187 314 560 439 275 0 1 67 96 90 130 99 255 0 2.5Portugal 1995 11 215 363 328 200 173 164 7 139 172 87 33 42 85 2.62000 8 147 375 349 208 140 140 5 114 154 87 41 25 64 2.82005 5 85 227 284 181 90 93 5 7 67 109 66 29 11 42 1 2.92010 3 55 110 199 152 70 76 0 3 54 62 54 36 10 28 0 2.72011 –Republic of 1995 0 55 115 166 95 65 15 2 42 38 31 19 10 12 3.3Moldova 2000 2 52 31 36 13 13 6 1 16 32 45 23 14 6 1.12005 2 211 337 345 313 106 31 0 3 97 92 57 61 23 18 0 3.82010 0 119 243 244 248 113 21 0 6 47 90 46 47 23 20 0 3.52011 2 94 257 250 267 107 21 0 3 66 79 51 41 20 14 0 3.6Romania 1995 387 1 662 2 322 3 608 2 587 1 751 784 355 1 352 1 240 871 479 396 417 2.62000 46 832 1 508 1 799 1 684 916 533 53 701 766 484 341 207 321 2.52005 36 752 1 511 1 786 1 999 952 638 4 55 758 780 493 374 219 442 2 2.52010 21 669 865 1 336 1 293 895 567 0 40 503 477 400 275 172 438 0 2.42011 19 623 807 1 189 1 099 833 540 0 27 473 513 403 212 198 426 0 2.3Russian 1995 –Federation 2000 1 295 526 596 402 151 54 1 43 73 74 38 31 44 6.72005 –2010 8 2 228 6 276 5 571 5 361 2 787 920 0 28 1 247 2 554 1 719 1 182 745 790 0 2.82011 15 1 826 5 726 5 338 4 928 2 664 845 36 1 139 2 394 1 643 1 166 719 752 2.7San Marino 1995 –2000 1 –2005 –2010 –2011 –Serbia 2005 3 62 96 118 156 112 132 0 6 69 76 55 49 22 149 0 1.62010 2 76 70 93 116 83 109 0 5 66 74 46 39 34 164 0 1.32011 2 60 73 74 122 112 101 0 5 46 59 43 30 20 129 0 1.6Serbia & 1995 10 108 204 317 296 350 386 11 127 167 133 83 158 275 1.8Montenegro 2000 –Slovakia 1995 4 18 44 123 108 63 152 5 16 17 22 24 33 159 1.92000 2 6 15 31 50 16 32 0 5 9 7 5 4 54 1.82005 0 3 13 16 25 25 20 0 0 1 8 9 5 6 27 0 1.82010 1 7 7 18 17 17 15 0 0 1 6 7 2 3 11 0 2.72011 0 6 8 6 20 16 13 0 0 2 3 4 6 1 11 0 2.6236 Data can be downloaded from www.who.int/tb/data GLOBAL TUBERCULOSIS REPORT 2012
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GLOBALTUBERCULOSISREPORT2012
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ContentsAbbreviationsivAcknowledgem
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AcknowledgementsThis report on glob
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WHO Western Pacific RegionShalala A
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Executive SummaryThe World Health O
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CHAPTER 1IntroductionBOX 1.1Basic f
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TABLE 1.1 Targets for the scale-up
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TABLE 1.2 Reporting of data in the
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BOX 2.1Uncertainty in estimates of
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TABLE 2.2 Estimated burden of disea
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FIGURE 2.5 Estimated TB incidence r
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FIGURE B2.2.1Reporting of notificat
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FIGURE 2.8Estimated TB incidence ra
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FIGURE 2.11 Countries (in blue) for
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FIGURE 2.12 Trends in estimated TB
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● producing and widely disseminat
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FIGURE 2.16 Progress in global cove
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BOX 2.6Efforts by the Task Force to
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CHAPTER 3TB case notificationsand t
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BOX 3.1 1Definitions of TB casesDef
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TABLE 3.3 Contribution of public-pr
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BOX 3.4Integrating community-based
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TABLE 3.4 Estimates of the case det
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TABLE 3.5 Treatment success for new
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CHAPTER 4Drug-resistant TBKEY FACTS
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FIGURE 4.2 Percentage of new TB cas
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BOX 4.1Frequencies of resistance to
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FIGURE 4.6 Number of MDR-TB cases e
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FIGURE 4.7Notified cases of MDR-TB
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egimens globally, providing more su
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5.1 Funding for TB care and control
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TABLE 5.2 NTP budgets, available fu
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FIGURE 5.5Trends in domestic and do
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FIGURE 5.6Domestic funding as a per
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FIGURE 5.8Cost per TB patient succe
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FIGURE 5.10 Total cost and unit cos
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● The 14 countries not included i
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on public health by an external Exp
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evised as a result of the introduct
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TABLE 6.2 Incorporation of WHO poli
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FIGURE 6.3The Supranational Referen
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of TB disease by 65%, irrespective
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FIGURE 7.3Percentage of TB patients
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BOX 7.1Accelerating progress in pro
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TABLE 7.2 Assumptions used to estim
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FIGURE 8.1 The development pipeline
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sputum specimens and TB isolates fr
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cal trial sites and building labora
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new TB vaccine candidate. A Phase I
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This annex explains the methods tha
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2011. On average, 15 data points we
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may suffer from biases. These biase
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TABLE A1.3Parameter estimates used
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5. Estimates of TB prevalence, 1990
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the Republic of Moldova, Romania, t
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AFGHANISTANPopulation 2011 32 milli
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BRAZILPopulation 2011 197 millionHI
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CHINAPopulation 2011 1 348 millionH
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ETHIOPIAPopulation 2011 85 millionH
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INDONESIAPopulation 2011 242 millio
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MOZAMBIQUEPopulation 2011 24 millio
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NIGERIAPopulation 2011 162 millionH
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PHILIPPINESPopulation 2011 95 milli
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SOUTH AFRICAPopulation 2011 50 mill
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UGANDAPopulation 2011 35 millionHIG
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VIET NAMPopulation 2011 89 millionH
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ANNEX 3Regional profiles
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WHO REGION OF THE AMERICASPopulatio
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WHO EUROPEAN REGIONPopulation 2011
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WHO WESTERN PACIFIC REGIONPopulatio
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SUMMARY BY WHO REGIONTable A4.1 Est
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MORTALITY (EXCLUDING HIV) PREVALENC
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NEW AND RELAPSENOTIFICATION RATE aY
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-% OF TB PATIENTS WITHKNOWN HIV STA
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AFRICAN REGIONTable A4.1 Estimates
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INCIDENCE (INCLUDING HIV) INCIDENCE
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NEW AND RELAPSENOTIFICATION RATE aY
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NEW AND RELAPSENOTIFICATION RATE a1
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TREATMENT SUCCESS (%) a1995-2010YEA
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-% OF TB PATIENTS WITHKNOWN HIV STA
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YEARTOTALCONFIRMEDCASES OFMDR-TB aE
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MALEYEAR 0-14 15-24 25-34 35-44 45-
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REGION OF THE AMERICASTable A4.1 Es
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INCIDENCE (INCLUDING HIV) INCIDENCE
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Page 190 and 191:
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% OF COHORTTREATMENT SUCCESS (%) a1
Page 194 and 195: % OF COHORTTREATMENT SUCCESS (%) a1
Page 198 and 199: -% OF TB PATIENTS WITHKNOWN HIV STA
Page 200 and 201: YEARTOTALCONFIRMEDCASES OFMDR-TB aE
Page 202 and 203: MALEFEMALEYEAR 0-14 15-24 25-34 35-
Page 204 and 205: EASTERN MEDITERRANEAN REGIONTable A
Page 206 and 207: MORTALITY (EXCLUDING HIV) PREVALENC
Page 208 and 209: INCIDENCE (INCLUDING HIV) INCIDENCE
Page 210 and 211: NEW AND RELAPSENOTIFICATION RATE a1
Page 220 and 221: EUROPEAN REGIONTable A4.1 Estimates
Page 248 and 249: SOUTH-EAST ASIA REGIONTable A4.1 Es
Page 258: SMEAR LABS % OF SMEARPER 100K LABS
Page 261 and 262: Estimates of mortality, prevalence
Page 263 and 264: YEARPOPULATION(MILLIONS)MORTALITY (
Page 265 and 266: YEARPOPULATION(MILLIONS)INCIDENCE (
Page 267 and 268: YEARPOPULATION(MILLIONS)INCIDENCE (
Page 271 and 272: TREATMENT SUCCESS (%) a1995-2010YEA
Page 273 and 274: TREATMENT SUCCESS (%) a1995-2010YEA
Page 281 and 282: SMEAR LABS % OF SMEARPER 100K LABS
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