Global Tuberculosis Report -- 2012.pdf

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YEARTOTALCONFIRMEDCASES OFMDR-TB aESTIMATED CASESOF MDR-TB AMONGNOTIFIEDESTIMATED CASESOF MDR-TB AMONGNOTIFIEDNEW PULMONARY CASESNUMBER OFBACT+VE bTESTED FORMDR-TB% OFBACT+VE bTESTED FORMDR-TBESTIMATED CASESOF MDR-TB AMONGNOTIFIEDPREVIOUSLY TREATED CASESNUMBER OFNOTIFIEDTESTED FORMDR-TB% OF NOTIFIEDTESTED FORMDR-TBHonduras 2005 3 3 0.13 0 02009 4 27 1.4 43 192010 9 57 3.1 62 322011 5 70 (35–110) 47 (20–92) 30 1.5 23 (11–42) 65 34Jamaica 2005 0 11 19 2 402009 0 67 87 –2010 1 40 31 5 262011 1 2.5 (1.1–3.9) 2.1 (0.69–3.3) 28 64 0.44 (0.17–0.71) 1 25Mexico 2005 394 314 2.1 74 3.72009 11 1
MALEFEMALEYEAR 0–14 15–24 25–34 35–44 45–54 55–64 65+0–14 15–24 25–34 35–44 45–54 55–64 65+UN-KNOWNUN-KNOWNMALE:FEMALERATIOAnguilla 1995 –2000 –2005 –2010 0 0 0 0 0 0 1 0 0 0 0 0 0 0 –2011 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –Antigua and 1995 –Barbuda 2000 0 0 0 0 0 0 1 1 1 1 0 0 0 0 0.332005 1 1 2 2 0.502010 0 0 2 0 2 1 0 0 0 0 1 0 0 0 0 0 5.02011 0 0 1 1 3 1 1 0 0 1 0 0 0 0 0 0 7.0Argentina 1995 –2000 97 278 594 402 419 368 330 121 544 479 262 230 179 216 1.22005 64 621 530 358 384 340 348 90 530 474 290 198 169 240 1.32010 56 536 491 309 302 340 282 2 59 421 426 233 184 153 176 1 1.42011 143 664 657 434 397 358 289 9 142 587 470 279 192 169 213 4 1.4Aruba 1995 –2000 –2005 –2010 –2011 4 1 1 1 2.5Bahamas 1995 3 3 5 7 4 2 2 0 1 7 2 0 0 1 2.42000 1 2 7 9 4 3 2 2 5 7 8 2 3 1 1.02005 –2010 0 2 3 5 0 2 0 0 0 5 1 1 0 0 0 0 1.72011 0 2 3 6 2 2 1 0 0 1 3 3 0 0 0 0 2.3Barbados 1995 –2000 0 0 0 2 0 0 0 0 0 1 0 0 0 0 2.02005 –2010 0 0 0 1 2 0 0 0 0 1 0 0 2 0 0 0 1.02011 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –Belize 1995 1 1 2 4 0 1 1 0 6 2 0 1 1 2 0.832000 2 5 7 2 6 3 5 0 2 1 2 4 1 4 2.12005 0 8 8 6 8 5 3 0 4 4 4 3 2 4 1.82010 2 9 16 22 24 11 18 4 5 7 7 9 4 5 2.52011 0 8 14 9 16 2 0 0 2 0 8 4 1 0 3.3Bermuda 1995 –2000 –2005 –2010 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 –2011 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –Bolivia 1995 –(Plurinational 2000 166 1 182 797 518 466 340 366 191 831 588 334 254 192 233 1.5State of) 2005 157 1 320 725 439 391 346 415 160 846 533 276 226 182 262 1.52010 95 1 150 622 415 395 338 409 119 744 471 238 191 162 264 1.62011 100 1 231 685 372 371 302 457 146 778 459 235 183 155 272 1.6Bonaire, Saint 2010 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –Eustatius and Saba 2011 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –Brazil 1995 –2000 1 894 7 268 11 568 11 906 8 623 5 085 4 494 1 859 6 719 7 215 5 395 3 582 2 384 2 496 1.72005 317 5 074 6 119 6 128 5 259 2 803 2 140 355 3 496 3 663 2 626 1 897 1 112 1 104 2.02010 298 4 405 6 381 5 293 4 762 2 875 1 947 43 280 2 677 3 008 2 211 1 720 1 038 979 15 2.22011 336 4 877 6 755 5 462 5 054 3 083 2 142 41 356 2 815 3 131 2 230 1 779 1 164 1 069 0 2.2British Virgin 1995 –Islands 2000 1 –2005 –2010 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 –2011 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –Canada 1995 1 28 31 60 34 41 70 7 33 28 22 12 18 51 1.52000 5 34 45 46 41 32 79 4 33 40 30 25 12 66 1.32005 3 37 45 44 40 20 68 6 28 40 27 24 13 37 1.52010 3 30 28 36 32 25 62 0 1 28 24 16 10 19 44 0 1.52011 2 34 36 31 40 33 70 0 3 23 29 28 14 9 55 0 1.5Cayman Islands 1995 –2000 0 0 3 1 0 1 0 –2005 –2010 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 1.02011 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 –Chile 1995 24 148 182 204 155 141 163 24 100 120 108 75 73 107 1.72000 6 81 160 198 150 132 126 10 66 96 70 54 58 83 2.02005 3 74 128 179 162 115 133 4 55 78 60 56 36 93 2.12010 2 90 115 144 159 122 157 0 6 56 76 59 56 40 72 0 2.22011 4 88 139 143 164 127 134 0 6 62 75 66 69 48 71 0 2.0Colombia 1995 –2000 246 763 1 030 963 743 610 746 194 587 758 523 381 304 510 1.62005 178 623 685 666 687 510 695 179 581 533 457 389 292 395 1.42010 148 602 765 540 710 610 814 0 146 560 576 428 374 284 471 0 1.52011 105 663 714 558 702 594 753 0 98 461 535 324 337 278 390 0 1.7Costa Rica 1995 1 17 38 24 19 23 22 2 17 15 11 7 9 14 1.92000 14 31 53 62 39 28 49 13 21 33 24 20 23 24 1.72005 1 43 38 53 34 20 34 1 21 31 18 16 6 14 2.12010 2 18 48 33 27 22 28 1 0 18 20 12 14 15 8 1 2.02011 0 23 24 29 33 22 36 0 2 18 27 23 19 12 17 0 1.4Cuba 1995 2 59 118 83 75 75 156 1 17 52 29 39 48 80 2.12000 0 71 167 90 74 55 75 2 9 22 26 22 23 39 3.72005 2 20 73 90 50 58 51 2 14 17 26 13 22 29 2.82010 3 17 61 89 78 53 57 0 1 15 15 14 16 17 26 0 3.42011 2 14 51 83 86 50 48 0 1 6 18 18 17 17 26 0 3.2Curaçao 2010 0 0 0 2 1 0 0 0 0 1 1 0 0 0 0 0 1.52011 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –Dominica 1995 –2000 –2005 –2010 0 0 0 0 0 3 1 0 0 0 0 1 2 1 0 0 1.02011 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 –Dominican 1995 –Republic 2000 73 410 481 344 173 125 113 65 317 325 212 115 79 75 1.42005 43 399 483 386 228 123 105 57 339 332 209 119 72 54 1.52010 29 276 346 292 170 112 85 0 43 239 207 142 102 54 62 0 1.52011 20 333 406 318 200 133 112 0 30 242 274 159 103 66 58 0 1.6Ecuador 1995 –2000 –2005 48 446 468 308 237 150 159 48 329 305 199 139 85 127 1.52010 32 499 529 314 309 227 246 52 298 308 178 158 113 110 1.82011 45 481 547 364 323 272 232 49 340 311 177 141 118 121 1.8El Salvador 1995 –2000 13 99 124 114 92 62 107 28 81 76 63 63 39 47 1.52005 5 97 140 128 104 74 117 6 85 82 59 50 42 70 1.72010 5 101 170 96 77 62 101 0 6 63 65 49 58 51 68 0 1.72011 3 114 183 106 96 77 115 0 6 61 61 44 52 69 92 0 1.8Grenada 1995 –2000 –2005 –2010 1 1 1 1 3.02011 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 –192 Data can be downloaded from www.who.int/tb/data GLOBAL TUBERCULOSIS REPORT 2012
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GLOBALTUBERCULOSISREPORT2012
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ContentsAbbreviationsivAcknowledgem
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AcknowledgementsThis report on glob
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WHO Western Pacific RegionShalala A
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Executive SummaryThe World Health O
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CHAPTER 1IntroductionBOX 1.1Basic f
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TABLE 1.1 Targets for the scale-up
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TABLE 1.2 Reporting of data in the
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BOX 2.1Uncertainty in estimates of
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TABLE 2.2 Estimated burden of disea
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FIGURE 2.5 Estimated TB incidence r
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FIGURE B2.2.1Reporting of notificat
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FIGURE 2.8Estimated TB incidence ra
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FIGURE 2.11 Countries (in blue) for
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FIGURE 2.12 Trends in estimated TB
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● producing and widely disseminat
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FIGURE 2.16 Progress in global cove
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BOX 2.6Efforts by the Task Force to
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CHAPTER 3TB case notificationsand t
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BOX 3.1 1Definitions of TB casesDef
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TABLE 3.3 Contribution of public-pr
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BOX 3.4Integrating community-based
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TABLE 3.4 Estimates of the case det
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TABLE 3.5 Treatment success for new
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CHAPTER 4Drug-resistant TBKEY FACTS
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FIGURE 4.2 Percentage of new TB cas
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BOX 4.1Frequencies of resistance to
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FIGURE 4.6 Number of MDR-TB cases e
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FIGURE 4.7Notified cases of MDR-TB
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egimens globally, providing more su
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5.1 Funding for TB care and control
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TABLE 5.2 NTP budgets, available fu
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FIGURE 5.5Trends in domestic and do
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FIGURE 5.6Domestic funding as a per
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FIGURE 5.8Cost per TB patient succe
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FIGURE 5.10 Total cost and unit cos
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● The 14 countries not included i
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on public health by an external Exp
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evised as a result of the introduct
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TABLE 6.2 Incorporation of WHO poli
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FIGURE 6.3The Supranational Referen
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of TB disease by 65%, irrespective
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FIGURE 7.3Percentage of TB patients
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BOX 7.1Accelerating progress in pro
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TABLE 7.2 Assumptions used to estim
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FIGURE 8.1 The development pipeline
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sputum specimens and TB isolates fr
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cal trial sites and building labora
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new TB vaccine candidate. A Phase I
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This annex explains the methods tha
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2011. On average, 15 data points we
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may suffer from biases. These biase
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TABLE A1.3Parameter estimates used
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5. Estimates of TB prevalence, 1990
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the Republic of Moldova, Romania, t
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AFGHANISTANPopulation 2011 32 milli
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BRAZILPopulation 2011 197 millionHI
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CHINAPopulation 2011 1 348 millionH
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ETHIOPIAPopulation 2011 85 millionH
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INDONESIAPopulation 2011 242 millio
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MOZAMBIQUEPopulation 2011 24 millio
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NIGERIAPopulation 2011 162 millionH
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PHILIPPINESPopulation 2011 95 milli
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SOUTH AFRICAPopulation 2011 50 mill
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UGANDAPopulation 2011 35 millionHIG
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VIET NAMPopulation 2011 89 millionH
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ANNEX 3Regional profiles
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WHO REGION OF THE AMERICASPopulatio
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WHO EUROPEAN REGIONPopulation 2011
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WHO WESTERN PACIFIC REGIONPopulatio
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SUMMARY BY WHO REGIONTable A4.1 Est
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Page 152 and 153: NEW AND RELAPSENOTIFICATION RATE aY
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Page 156 and 157: AFRICAN REGIONTable A4.1 Estimates
Page 162 and 163: INCIDENCE (INCLUDING HIV) INCIDENCE
Page 164 and 165: NEW AND RELAPSENOTIFICATION RATE aY
Page 166 and 167: NEW AND RELAPSENOTIFICATION RATE a1
Page 168 and 169: TREATMENT SUCCESS (%) a1995-2010YEA
Page 176 and 177: YEARTOTALCONFIRMEDCASES OFMDR-TB aE
Page 178 and 179: MALEYEAR 0-14 15-24 25-34 35-44 45-
Page 180 and 181: REGION OF THE AMERICASTable A4.1 Es
Page 192 and 193: % OF COHORTTREATMENT SUCCESS (%) a1
Page 202 and 203: MALEFEMALEYEAR 0-14 15-24 25-34 35-
Page 204 and 205: EASTERN MEDITERRANEAN REGIONTable A
Page 220 and 221: EUROPEAN REGIONTable A4.1 Estimates
Page 242 and 243: YEARTOTALCONFIRMEDCASES OFMDR-TB aE
Page 248 and 249: SOUTH-EAST ASIA REGIONTable A4.1 Es
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MORTALITY (EXCLUDING HIV) PREVALENC
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NEW AND RELAPSENOTIFICATION RATE a1
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% OF COHORTTREATMENT SUCCESS (%) a1
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YEARTOTALCONFIRMEDCASES OFMDR-TB aE
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SMEAR LABS % OF SMEARPER 100K LABS
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Estimates of mortality, prevalence
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YEARPOPULATION(MILLIONS)MORTALITY (
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YEARPOPULATION(MILLIONS)INCIDENCE (
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YEARPOPULATION(MILLIONS)INCIDENCE (
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NEW AND RELAPSENOTIFICATION RATE a1
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TREATMENT SUCCESS (%) a1995-2010YEA
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TREATMENT SUCCESS (%) a1995-2010YEA
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-% OF TB PATIENTS WITHKNOWN HIV STA
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YEARTOTALCONFIRMEDCASES OFMDR-TB aE
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MALEFEMALEYEAR 0-14 15-24 25-34 35-
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SMEAR LABS % OF SMEARPER 100K LABS
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