Book 4 - Self Instructional Manual for Cancer Registrars - SEER ...

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Answer:Q18White blood cells which are known as leukocytes function as a defense or protectionagainst invading microorganisms (infection) or as a reaction to treatment by radiationand/or chemotherapy.Answer:Q19When a blood clot forms in and clogs a vessel, it is called a thrombus. When a blood clotbreaks loose from an area in a vein and travels to another area and becomes lodged there,it is called an embolus.122
LeukemiaLeukemia is a malignant disease of the blood-forming organs. As with other malignant diseases,leukemia is characterized by an uncontrolled proliferation of cells, in this case the white blood cellsor leukocytes. However, an elevated leukocyte count usually represents a nonneoplastic reaction toinfection or treatment by radiation and/or chemotherapy.Leukemias are classified according to the type and number (percent) of abnormal cells and therapidity of the clinical course. The predominant cell types are:• Lymphocytic• Myeloid/Granulocytic• MonocyticLeukemias are diagnosed by the microscopic detection of abnormal cells in the circulating(peripheral) blood and in the bone marrow. These abnormal cells may be described as atypical,immature, or "blast forms"--lymphoblasts, myeloblasts, or monoblasts. These are terms for immaturecells which have not yet developed into the mature forms, namely, lymphocytes, granulocytes, ormonocytes. The presence of myelocytes, metamyelocytes, or promyelocytes indicates granulocytic(myelocytic) leukemia; prolymphocytes indicate lymphatic (or lymphocytic) leukemia, andpromonocytes indicate monocytic leukemia. In some cases the cells may be so undifferentiated orimmature that they are impossible to identify and the disease may be classified as stem cell or blasticleukemia. You will recognize these terms in the outline (page 124) showing the development ofwhite blood cells from stem cells. During the development of blood cells in the bone marrow, theprimitive immature (unspecialized) stem cells change shape and structure several times in the courseof becoming mature differentiated (specialized) blood cells.123
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SEER ProgramSelf Instructional Manu
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CONTENTSBOOK 4: HUMAN ANATOMY AS RE
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ILLUSTRATIONS(Figures 1-82, cont'd)
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ACKNOWLEDGEMENTSPortions of Book 4
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SECTIONAOBJECTIVES AND CONTENT OF B
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BSECTIONBTERMS USED TO INDICATE BOD
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Directional Planes of the BodySagit
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Relative Positional and Directional
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Figure 3. ANATOMIC DIVISIONSOF THE
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Answers to Practical ExerciseNote t
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SECTIONCTHE INTEGUMENTARYSYSTEM19
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EpidermisThe epidermis (Figure 4A)
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Q1a. What are the two primary layer
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Epidermis is epithelial tissue deri
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Answer:Q2The three glands of the sk
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Q3Q4Accessory skin organs are found
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Benign TumorsThere is a large group
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Q5 Match the malignant tumors of th
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MalignantMelanomaMalignant melanoma
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The description of the level 1 of i
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Q9"Clark's Classification" of malig
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Lymphatic Drainage of the SkinThe l
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Q10Match the regions of the skin on
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SECTIONTHE LYMPHATICDSYSTEM51
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T-Cells Versus B-CeilsThe two princ
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Answer:Q1The lymphatic system colle
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Figures 8A-8B. LYMPHATIC DRAINAGE O
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Answer:Q3The lymphatic system colle
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Lymph nodes accomplish two separate
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Q6The lymph nodes have two main fun
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SpleenThe spleen, the largest lymph
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Q9Match each lymphatic organ or tis
Page 79 and 80: LymphaticDrainageLymph nodes, most
Page 81 and 82: Answer:QllLymphatics tend to parall
Page 83 and 84: Q14A general term for lymph nodes l
Page 85: Lymph Nodes of the ThoraxThe lymph
Page 88 and 89: Answer:Q18Lymph nodes of the thorax
Page 91 and 92: Q20Lymph nodes of the abdomen may a
Page 93: Lymph Nodes of Upper and Lower Extr
Page 96 and 97: Answer:Q22c 1. Popliteal Heela 2. A
Page 98 and 99: Hodgkin's disease. The histologic c
Page 100 and 101: Answer:Q23Benign tumors of lymphoid
Page 102 and 103: Extralymphatic/ExtranodalSitesLymph
Page 104 and 105: Answer:Q27Non-Hodgkin's lymphomas m
Page 106 and 107: TilE CARDIOVASCULAR SYSTEMIonatod
Page 108 and 109: CIRCULATORY SYSTEMFigure 14D. BLOOD
Page 110 and 111: Answer:Q1The cardiovascular system
Page 112 and 113: The heart lies in a loose-fitting s
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Page 116 and 117: Answer:Q5The heart has four chamber
Page 118 and 119: Answer:QIODeoxygenated blood from t
Page 120 and 121: Portal System (portal circulation)V
Page 122 and 123: Answer:QllThe three kinds of blood
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Page 126 and 127: Answer:QlgThe three main types of b
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Page 132 and 133: DEVELOPMENTOF WHITE BLOOD CELLSStem
Page 134 and 135: Answer:Q20Malignant diseases of the
Page 136 and 137: Answer:Q25b 1. Leukemia An uncontro
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Page 142 and 143: Answer:Q1The parts of the respirato
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Page 146 and 147: Answer:Q41. Serves as a passageway
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Page 150 and 151: Answer:Q7The pharynx can be divided
Page 152 and 153: The larynx can be divided into thre
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Page 156 and 157: Answer:Q10The three single cartilag
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Page 160 and 161: Answer:Q14The windpipe or trachea s
Page 162 and 163: The lungs provide a place where lar
Page 164 and 165: Answer:Q16The main bronchus, pulmon
Page 166 and 167: Clinical ManifestationsClinical man
Page 168 and 169: Answer:Q19The interpleural space ma
Page 170 and 171: Answer:Q24_g_ 1. Exchange of oxygen
Page 172 and 173: DIGESTIVE SYSTEM: Esophagus-RectumP
Page 174 and 175: The organs of the digestive system
Page 176 and 177: Answer:Q1The main organs of the dig
Page 178 and 179: • Lips. The lips form the upper a
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Answer:Q5The lip consists of an exp
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Malignant TumorsMalignant lesions a
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Answer:Q8The tongue is composed of
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• Gums (gingiva). The gums are fo
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Answer:Qllb__ 1. GumMucosal coverin
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182
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Answer:Q12The palate is the roof of
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Answer:Q18The major salivary glands
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Answer:Q21c 1. Gum Retropharyngeala
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Oropharynx. The air and food passag
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196
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Answer:Q23Another name for the hypo
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Answer:Q25a__ 1. HypopharynxServes
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Answer:Q28a. Tonsillar pillar - Oro
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Figure 31. MEASUREMENTS OF THE ESOP
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206
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Answer:Q30The esophagus extends fro
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The medial border of the stomach is
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Q33The stomach lies just below thei
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Answer:Q33The stomach lies just bel
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Answer:Q38The small intestine is ab
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The large intestine receives the fl
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Malignantand Benign TumorsThe usual
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224
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Answer:Q41The large intestine is ab
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Answer:Q433. The ileocolic lymph no
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Metastatic tumors involving the liv
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Answer:Q45The most common primary t
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234
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Answer: 046The function of the gall
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238
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Answer:Q48.The pancreas plays an im
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Figure 39. PRINCIPAL PARTS OF THE U
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The microscopic structure of the re
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Answer:Q1The urinary system consist
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Figure 41. A NEPHRON_ Otomes_JLus_;
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250
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Answer:Q4The blood is circulated th
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254
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Answer:Q8The regional lymph node dr
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258
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Answer:Q12The tube which carries ur
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URINARY BLADDER, RENAL PELVIS AND U
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Malignant TumorsBladder cancer is t
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Answer:Q14The urinary bladder is a
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Q18Theis a membranous tube which co
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Answer:Q18The urethra is a membrano
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Figure 44.FEMALE PELVIS (frontal vi
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CORPUSUTERII I _ 'PRIMARY] ENDOMETR
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Answer:Q1The female reproductiveorg
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• Choriocarcinoma, a highly malig
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Answer:Q6For corpus uteri you might
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FallopiantubesThe fallopian tubes,
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Answer:Q7b 1. Uterus Pear-shaped mu
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Q8Name the three openings of the ut
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Answer: 08In naming the three openi
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Regional Lymph NodesThe regional ly
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6. Vaginal orifice f. Glands that s
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Answer:Q14The vagina is situated be
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298
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Answer:Q19The breasts overlie the p
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A tumor specified as "subareolar" i
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Answer:Q22One of the first and most
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306
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ANSWERS TO REVIEW TESTd 1. Gonads i
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310
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Answer:Q25The male gonads consist o
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314
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Answer:Q27c 1. Epididymis Tube loca
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Figure 51. PROSTATE GLAND (frontal
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Answer:Q29b 1. Prostate Gland which
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RegionalLymph NodesThe regional lym
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324
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Answer:Q30Male hormones are produce
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Figure 53. ENDOCRINEGLANDS328
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• Prolactin (luteotrophic hormone
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Parathyroid GlandThere are four par
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Thymus GlandThe thymus gland is loc
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Q2Match the hormone on the left wit
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Answer:Q1d 1. Hormones Organic secr
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340
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Figure 58.AXIAL SKELETONSkuLl.342
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344
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Answer:Q1The skeletal system is com
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348
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Answer:Q4One characteristic which d
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352
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Answer:Q8The purpose of the sesamoi
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Structure of BoneEach long bone of
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Answer:QllThe numbered parts of the
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Facial bones. The facial bones are
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Figure 65. BONES OF THE THORAX Figu
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Q17Match the bones on the left with
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Figure 67. APPENDICULARSKELETON366
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Malignant TumorsBone is derived fro
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Q20Sites from which metastases to b
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Q22Match the description on the lef
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Answer:Q21c 1. Angiosarcoma A malig
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Figure 68.MUSCLE TYPES376
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Figure 69. HISTOLOGICAL COMPARISONS
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Answer:Q1The three types of muscle
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382
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Answer:Q61. True Malignant tumors o
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• Supinators turn the palm upward
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Answer:Q8The three general function
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Answer:Q11Match the muscle groups o
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392
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Figure 70.NERVE CELL (neuron)394
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Answer:Q1The central nervous system
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Figure 71.CEREBRUMCEREBRUMC_ere_etr
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400
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Figure 74 CRANIAL NERVES402
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MalignantTumorsGliomas are tumors o
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406
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Answer:Q6Match each term on the lef
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410
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412
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Answer:Q1The five major sensesof th
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416
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Answer:Q3The three layers which com
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420
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Answer:Q5The eyeball/s not a solid
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424
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Answer:Q8Name the lymph nodes which
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Figure 80. TONGUE: Areas of tasteUv
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Answer:QllReceptors for the sense o
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Malignant TumorsTumors of the nasal
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Answer:Q13The nasal fossa is divide
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Regional Lymph NodesThe lymphatics
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Answer:Q16b 1. External ear Made up
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440
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HISTOLOGIC TYPE PRIMARY SITELeukemi
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444
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DETERMINATION OF SUBSEQUENT PRIMARI
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470
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OTHER ICD-O-2 CODES TO BE CONSIDERE
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474
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SELECTED BIBLIOGRAPHY (cont'd)Paul,
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478
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Adenocarcinoma (continued)Primary s
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Arteries (see also Vessels) (contin
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Blood (see also Cardiovascular syst
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Bone tissue (osseous, vascular tiss
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Breast (mammary gland) (continued)H
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Cartilage (nonvascular tissue) (con
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Cerebrum (forebrain, telencephalon)
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Cortisol, 329, 333, 336, 338Cortiso
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Ducts (see also Endocrine system an
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Estradiol, 281Estrogen-producing ca
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Follicular adenocarcinoma, 331, 337
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Glycogen, 229Gonadotrophic hormone
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Histologic type of cancer, 439-441H
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Integumentary system (skin) (contin
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Kidney (see also Urinary system) (c
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Leukocyte (WBC),Agranular, 119B-Cel
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Luteal cell, 281Luteinizing hormone
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Lymph nodes (continued)Perivesical,
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Lymphoma (continued)Nasopharynx (ph
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Metastases (continued)Lymph node, 6
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Muscle (see also Muscular system) (
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Nervous system, Cranial (continued)
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Ovary (female gonad), 273, 281,285,
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Peripheral nervous system, 393, 396
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Prostate (continued)Urethra (prosta
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Salivary gland (see also Parotid, S
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Skull (diploe), 351, 354, 356, 359,
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Sulcus,Buccal, 178Nasolabial, 39Sup
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Tibia (shin bone), 351, 369Tumors o
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Tumor (see also specific histologic
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Urethra (female, male) (continued)L
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Vertebral cavity, 10Vertebral colum
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