Book 4 - Self Instructional Manual for Cancer Registrars - SEER ...

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MalignantTumorsA variety ol" malignant tumors also arise in the skin and may derive from epithelial and/orconnective tissue of the skin and its appendages. Many ol"these are felt to be related to prolongedexposure to sun rays. Individuals with light skin/decreased melanin are more susceptible. The mostcommon tumors are listed and described briefly below:• Basal cell carcinoma: A malignant skin tumor composed of cells similar to those in the basallayer of the epidermis• Squamous cell (epidermoid) carcinoma: A malignant tumor having characteristics ofsquamouscells• Basosquamous cell carcinoma: A malignant skin tumor of mixed basal and squamous cells• Bowen's disease: lntraepidermal (in-situ) squamous cell carcinoma• Dermatofibrosarcc)ma (protuberans): A l'ibrosarcoma o1"the skin, a low grade malignant tumorof the fibrous tissue of the dermis• Sweat gland adenocarcinoma: A malignant tumc)r o['sudoril'crous glandular epithelium• Sebaceous gland adenocarcinoma: A malignant tumor of sebaceous glandular epithelium• Kaposi's (multiple idiopathic hemorrhagic) sarcoma: A multifocal malignant vascular tumorcharacterized by bluish-red or brown plaques and nodules. Kaposi's sarcoma appears to bean opportunistic carcinoma in the presence o1'AIDS (acquired immune deficiency syndrome).• Mycosis fungicides: A malignant lymphtmla
Q5 Match the malignant tumors of the skin on the left with the best description on the right.1. Bowen's disease a. A malignant lymphoma of the skin2. Dermatofibrosarcoma b. Intraepidermal squamous cell carcinoma3. Kaposi's sarcoma c. A multifocal malignant tumor characterized bybluish red or brown plaques or nodules4. Mycosis fungoides d. A malignant tumor of the fibroustissue of the dermis5. Melanoma e. A malignant tumor of the melaninproducingcells37
Page 2 and 3: SEER ProgramSelf Instructional Manu
Page 4 and 5: CONTENTSBOOK 4: HUMAN ANATOMY AS RE
Page 6 and 7: ILLUSTRATIONS(Figures 1-82, cont'd)
Page 8 and 9: ACKNOWLEDGEMENTSPortions of Book 4
Page 11: SECTIONAOBJECTIVES AND CONTENT OF B
Page 15: BSECTIONBTERMS USED TO INDICATE BOD
Page 18 and 19: Directional Planes of the BodySagit
Page 20 and 21: Relative Positional and Directional
Page 22 and 23: Figure 3. ANATOMIC DIVISIONSOF THE
Page 24 and 25: Answers to Practical ExerciseNote t
Page 27: SECTIONCTHE INTEGUMENTARYSYSTEM19
Page 30 and 31: EpidermisThe epidermis (Figure 4A)
Page 33 and 34: Q1a. What are the two primary layer
Page 35: Epidermis is epithelial tissue deri
Page 38 and 39: Answer:Q2The three glands of the sk
Page 41 and 42: Q3Q4Accessory skin organs are found
Page 43: Benign TumorsThere is a large group
Page 47 and 48: MalignantMelanomaMalignant melanoma
Page 49: The description of the level 1 of i
Page 52 and 53: Q9"Clark's Classification" of malig
Page 54 and 55: Lymphatic Drainage of the SkinThe l
Page 57 and 58: Q10Match the regions of the skin on
Page 59: SECTIONTHE LYMPHATICDSYSTEM51
Page 62 and 63: T-Cells Versus B-CeilsThe two princ
Page 64 and 65: Answer:Q1The lymphatic system colle
Page 66 and 67: Figures 8A-8B. LYMPHATIC DRAINAGE O
Page 68 and 69: Answer:Q3The lymphatic system colle
Page 70 and 71: Lymph nodes accomplish two separate
Page 73 and 74: Q6The lymph nodes have two main fun
Page 75 and 76: SpleenThe spleen, the largest lymph
Page 77 and 78: Q9Match each lymphatic organ or tis
Page 79 and 80: LymphaticDrainageLymph nodes, most
Page 81 and 82: Answer:QllLymphatics tend to parall
Page 83 and 84: Q14A general term for lymph nodes l
Page 85: Lymph Nodes of the ThoraxThe lymph
Page 88 and 89: Answer:Q18Lymph nodes of the thorax
Page 91 and 92: Q20Lymph nodes of the abdomen may a
Page 93: Lymph Nodes of Upper and Lower Extr
Page 96 and 97:
Answer:Q22c 1. Popliteal Heela 2. A
Page 98 and 99:
Hodgkin's disease. The histologic c
Page 100 and 101:
Answer:Q23Benign tumors of lymphoid
Page 102 and 103:
Extralymphatic/ExtranodalSitesLymph
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Answer:Q27Non-Hodgkin's lymphomas m
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TilE CARDIOVASCULAR SYSTEMIonatod
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CIRCULATORY SYSTEMFigure 14D. BLOOD
Page 110 and 111:
Answer:Q1The cardiovascular system
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The heart lies in a loose-fitting s
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106
Page 116 and 117:
Answer:Q5The heart has four chamber
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Answer:QIODeoxygenated blood from t
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Portal System (portal circulation)V
Page 122 and 123:
Answer:QllThe three kinds of blood
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116
Page 126 and 127:
Answer:QlgThe three main types of b
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120
Page 130 and 131:
Answer:Q18White blood cells which a
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DEVELOPMENTOF WHITE BLOOD CELLSStem
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Answer:Q20Malignant diseases of the
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Answer:Q25b 1. Leukemia An uncontro
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130
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132
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Answer:Q1The parts of the respirato
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136
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Answer:Q41. Serves as a passageway
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140
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Answer:Q7The pharynx can be divided
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The larynx can be divided into thre
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146
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Answer:Q10The three single cartilag
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150
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Answer:Q14The windpipe or trachea s
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The lungs provide a place where lar
Page 164 and 165:
Answer:Q16The main bronchus, pulmon
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Clinical ManifestationsClinical man
Page 168 and 169:
Answer:Q19The interpleural space ma
Page 170 and 171:
Answer:Q24_g_ 1. Exchange of oxygen
Page 172 and 173:
DIGESTIVE SYSTEM: Esophagus-RectumP
Page 174 and 175:
The organs of the digestive system
Page 176 and 177:
Answer:Q1The main organs of the dig
Page 178 and 179:
• Lips. The lips form the upper a
Page 180 and 181:
Answer:Q5The lip consists of an exp
Page 182 and 183:
Malignant TumorsMalignant lesions a
Page 184 and 185:
Answer:Q8The tongue is composed of
Page 186 and 187:
• Gums (gingiva). The gums are fo
Page 188 and 189:
Answer:Qllb__ 1. GumMucosal coverin
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182
Page 192 and 193:
Answer:Q12The palate is the roof of
Page 194 and 195:
186
Page 196 and 197:
Answer:Q18The major salivary glands
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190
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Answer:Q21c 1. Gum Retropharyngeala
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Oropharynx. The air and food passag
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196
Page 206 and 207:
Answer:Q23Another name for the hypo
Page 208 and 209:
Answer:Q25a__ 1. HypopharynxServes
Page 210 and 211:
Answer:Q28a. Tonsillar pillar - Oro
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Figure 31. MEASUREMENTS OF THE ESOP
Page 214 and 215:
206
Page 216 and 217:
Answer:Q30The esophagus extends fro
Page 218 and 219:
The medial border of the stomach is
Page 220 and 221:
Q33The stomach lies just below thei
Page 222 and 223:
Answer:Q33The stomach lies just bel
Page 224 and 225:
216
Page 226 and 227:
Answer:Q38The small intestine is ab
Page 228 and 229:
The large intestine receives the fl
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Malignantand Benign TumorsThe usual
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224
Page 234 and 235:
Answer:Q41The large intestine is ab
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Answer:Q433. The ileocolic lymph no
Page 238 and 239:
Metastatic tumors involving the liv
Page 240 and 241:
Answer:Q45The most common primary t
Page 242 and 243:
234
Page 244 and 245:
Answer: 046The function of the gall
Page 246 and 247:
238
Page 248 and 249:
Answer:Q48.The pancreas plays an im
Page 250 and 251:
Figure 39. PRINCIPAL PARTS OF THE U
Page 252 and 253:
The microscopic structure of the re
Page 254 and 255:
Answer:Q1The urinary system consist
Page 256 and 257:
Figure 41. A NEPHRON_ Otomes_JLus_;
Page 258 and 259:
250
Page 260 and 261:
Answer:Q4The blood is circulated th
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254
Page 264 and 265:
Answer:Q8The regional lymph node dr
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258
Page 268 and 269:
Answer:Q12The tube which carries ur
Page 270 and 271:
URINARY BLADDER, RENAL PELVIS AND U
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Malignant TumorsBladder cancer is t
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Answer:Q14The urinary bladder is a
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Q18Theis a membranous tube which co
Page 278 and 279:
Answer:Q18The urethra is a membrano
Page 280 and 281:
Figure 44.FEMALE PELVIS (frontal vi
Page 282 and 283:
CORPUSUTERII I _ 'PRIMARY] ENDOMETR
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Answer:Q1The female reproductiveorg
Page 286 and 287:
• Choriocarcinoma, a highly malig
Page 288 and 289:
Answer:Q6For corpus uteri you might
Page 290 and 291:
FallopiantubesThe fallopian tubes,
Page 292 and 293:
Answer:Q7b 1. Uterus Pear-shaped mu
Page 294 and 295:
Q8Name the three openings of the ut
Page 296 and 297:
Answer: 08In naming the three openi
Page 298 and 299:
Regional Lymph NodesThe regional ly
Page 300 and 301:
6. Vaginal orifice f. Glands that s
Page 302 and 303:
Answer:Q14The vagina is situated be
Page 304 and 305:
296
Page 306 and 307:
298
Page 308 and 309:
Answer:Q19The breasts overlie the p
Page 310 and 311:
A tumor specified as "subareolar" i
Page 312 and 313:
Answer:Q22One of the first and most
Page 314 and 315:
306
Page 316 and 317:
ANSWERS TO REVIEW TESTd 1. Gonads i
Page 318 and 319:
310
Page 320 and 321:
Answer:Q25The male gonads consist o
Page 322 and 323:
314
Page 324 and 325:
Answer:Q27c 1. Epididymis Tube loca
Page 326 and 327:
Figure 51. PROSTATE GLAND (frontal
Page 328 and 329:
Answer:Q29b 1. Prostate Gland which
Page 330 and 331:
RegionalLymph NodesThe regional lym
Page 332 and 333:
324
Page 334 and 335:
Answer:Q30Male hormones are produce
Page 336 and 337:
Figure 53. ENDOCRINEGLANDS328
Page 338 and 339:
• Prolactin (luteotrophic hormone
Page 340 and 341:
Parathyroid GlandThere are four par
Page 342 and 343:
Thymus GlandThe thymus gland is loc
Page 344 and 345:
Q2Match the hormone on the left wit
Page 346 and 347:
Answer:Q1d 1. Hormones Organic secr
Page 348 and 349:
340
Page 350 and 351:
Figure 58.AXIAL SKELETONSkuLl.342
Page 352 and 353:
344
Page 354 and 355:
Answer:Q1The skeletal system is com
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348
Page 358 and 359:
Answer:Q4One characteristic which d
Page 360 and 361:
352
Page 362 and 363:
Answer:Q8The purpose of the sesamoi
Page 364 and 365:
Structure of BoneEach long bone of
Page 366 and 367:
Answer:QllThe numbered parts of the
Page 368 and 369:
Facial bones. The facial bones are
Page 370 and 371:
Figure 65. BONES OF THE THORAX Figu
Page 372 and 373:
Q17Match the bones on the left with
Page 374 and 375:
Figure 67. APPENDICULARSKELETON366
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Malignant TumorsBone is derived fro
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Q20Sites from which metastases to b
Page 380 and 381:
Q22Match the description on the lef
Page 382 and 383:
Answer:Q21c 1. Angiosarcoma A malig
Page 384 and 385:
Figure 68.MUSCLE TYPES376
Page 386 and 387:
Figure 69. HISTOLOGICAL COMPARISONS
Page 388 and 389:
Answer:Q1The three types of muscle
Page 390 and 391:
382
Page 392 and 393:
Answer:Q61. True Malignant tumors o
Page 394 and 395:
• Supinators turn the palm upward
Page 396 and 397:
Answer:Q8The three general function
Page 398 and 399:
Answer:Q11Match the muscle groups o
Page 400 and 401:
392
Page 402 and 403:
Figure 70.NERVE CELL (neuron)394
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Answer:Q1The central nervous system
Page 406 and 407:
Figure 71.CEREBRUMCEREBRUMC_ere_etr
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400
Page 410 and 411:
Figure 74 CRANIAL NERVES402
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MalignantTumorsGliomas are tumors o
Page 414 and 415:
406
Page 416 and 417:
Answer:Q6Match each term on the lef
Page 418 and 419:
410
Page 420 and 421:
412
Page 422 and 423:
Answer:Q1The five major sensesof th
Page 424 and 425:
416
Page 426 and 427:
Answer:Q3The three layers which com
Page 428 and 429:
420
Page 430 and 431:
Answer:Q5The eyeball/s not a solid
Page 432 and 433:
424
Page 434 and 435:
Answer:Q8Name the lymph nodes which
Page 436 and 437:
Figure 80. TONGUE: Areas of tasteUv
Page 438 and 439:
Answer:QllReceptors for the sense o
Page 440 and 441:
Malignant TumorsTumors of the nasal
Page 442 and 443:
Answer:Q13The nasal fossa is divide
Page 444 and 445:
Regional Lymph NodesThe lymphatics
Page 446 and 447:
Answer:Q16b 1. External ear Made up
Page 448 and 449:
440
Page 450 and 451:
HISTOLOGIC TYPE PRIMARY SITELeukemi
Page 452 and 453:
444
Page 454 and 455:
DETERMINATION OF SUBSEQUENT PRIMARI
Page 456 and 457:
Page 458 and 459:
Page 460 and 461:
Page 462 and 463:
Page 464 and 465:
Page 466 and 467:
Page 468 and 469:
Page 470 and 471:
Page 472 and 473:
Page 474 and 475:
Page 476 and 477:
Page 478 and 479:
470
Page 480 and 481:
OTHER ICD-O-2 CODES TO BE CONSIDERE
Page 482 and 483:
474
Page 484 and 485:
SELECTED BIBLIOGRAPHY (cont'd)Paul,
Page 486 and 487:
478
Page 488 and 489:
Adenocarcinoma (continued)Primary s
Page 490 and 491:
Arteries (see also Vessels) (contin
Page 492 and 493:
Blood (see also Cardiovascular syst
Page 494 and 495:
Bone tissue (osseous, vascular tiss
Page 496 and 497:
Breast (mammary gland) (continued)H
Page 498 and 499:
Cartilage (nonvascular tissue) (con
Page 500 and 501:
Cerebrum (forebrain, telencephalon)
Page 502 and 503:
Cortisol, 329, 333, 336, 338Cortiso
Page 504 and 505:
Ducts (see also Endocrine system an
Page 506 and 507:
Estradiol, 281Estrogen-producing ca
Page 508 and 509:
Follicular adenocarcinoma, 331, 337
Page 510 and 511:
Glycogen, 229Gonadotrophic hormone
Page 512 and 513:
Histologic type of cancer, 439-441H
Page 514 and 515:
Integumentary system (skin) (contin
Page 516 and 517:
Kidney (see also Urinary system) (c
Page 518 and 519:
Leukocyte (WBC),Agranular, 119B-Cel
Page 520 and 521:
Luteal cell, 281Luteinizing hormone
Page 522 and 523:
Lymph nodes (continued)Perivesical,
Page 524 and 525:
Lymphoma (continued)Nasopharynx (ph
Page 526 and 527:
Metastases (continued)Lymph node, 6
Page 528 and 529:
Muscle (see also Muscular system) (
Page 530 and 531:
Nervous system, Cranial (continued)
Page 532 and 533:
Ovary (female gonad), 273, 281,285,
Page 534 and 535:
Peripheral nervous system, 393, 396
Page 536 and 537:
Prostate (continued)Urethra (prosta
Page 538 and 539:
Salivary gland (see also Parotid, S
Page 540 and 541:
Skull (diploe), 351, 354, 356, 359,
Page 542 and 543:
Sulcus,Buccal, 178Nasolabial, 39Sup
Page 544 and 545:
Tibia (shin bone), 351, 369Tumors o
Page 546 and 547:
Tumor (see also specific histologic
Page 548 and 549:
Urethra (female, male) (continued)L
Page 550 and 551:
Vertebral cavity, 10Vertebral colum
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