Book 4 - Self Instructional Manual for Cancer Registrars - SEER ...

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T-Cells Versus B-CeilsThe two principal classes of lymphocytes that can be recognized in an immune system are T andB lymphoeytes. In recent years an attempt has been made to relate malignant lymphoma to thenormal cells of the immune system and to understand which parts of the immune system are involved.The T-cells mature in the thymus and are involved in cell-mediated immunity, that is, the cellsthemselves mediate the immune effect.The B-cells derive from a bone-marrow precursor and mature in the chicken in an organ knownas the bursa Fabricius. In humans and other mammals there is no bursa Fabricius, but B-cells maturein a bursa equivalent, which may be fetal liver. The B-cells, through their progeny, differentiate intoplasma cells. These are cells which can secrete antibodies and are known to <strong>for</strong>m the humoralcomponent of the immune system, that is, they secrete products which mediate the effect; it is notthe cell itself that is involved in the immune mechanism.54
Q1The lymphatic system collectslymphatic. Lymph is filtered through thefrom the tissues of the body via the, and finally it empties into the veins of the bloodcirculatorysystem.Q2Some specific lymphoid organs and tissues are:1.2.3.4.5.55
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SEER ProgramSelf Instructional Manu
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CONTENTSBOOK 4: HUMAN ANATOMY AS RE
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ILLUSTRATIONS(Figures 1-82, cont'd)
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ACKNOWLEDGEMENTSPortions of Book 4
Page 11: SECTIONAOBJECTIVES AND CONTENT OF B
Page 15: BSECTIONBTERMS USED TO INDICATE BOD
Page 18 and 19: Directional Planes of the BodySagit
Page 20 and 21: Relative Positional and Directional
Page 22 and 23: Figure 3. ANATOMIC DIVISIONSOF THE
Page 24 and 25: Answers to Practical ExerciseNote t
Page 27: SECTIONCTHE INTEGUMENTARYSYSTEM19
Page 30 and 31: EpidermisThe epidermis (Figure 4A)
Page 33 and 34: Q1a. What are the two primary layer
Page 35: Epidermis is epithelial tissue deri
Page 38 and 39: Answer:Q2The three glands of the sk
Page 41 and 42: Q3Q4Accessory skin organs are found
Page 43 and 44: Benign TumorsThere is a large group
Page 45 and 46: Q5 Match the malignant tumors of th
Page 47 and 48: MalignantMelanomaMalignant melanoma
Page 49: The description of the level 1 of i
Page 52 and 53: Q9"Clark's Classification" of malig
Page 54 and 55: Lymphatic Drainage of the SkinThe l
Page 57 and 58: Q10Match the regions of the skin on
Page 59: SECTIONTHE LYMPHATICDSYSTEM51
Page 64 and 65: Answer:Q1The lymphatic system colle
Page 66 and 67: Figures 8A-8B. LYMPHATIC DRAINAGE O
Page 68 and 69: Answer:Q3The lymphatic system colle
Page 70 and 71: Lymph nodes accomplish two separate
Page 73 and 74: Q6The lymph nodes have two main fun
Page 75 and 76: SpleenThe spleen, the largest lymph
Page 77 and 78: Q9Match each lymphatic organ or tis
Page 79 and 80: LymphaticDrainageLymph nodes, most
Page 81 and 82: Answer:QllLymphatics tend to parall
Page 83 and 84: Q14A general term for lymph nodes l
Page 85: Lymph Nodes of the ThoraxThe lymph
Page 88 and 89: Answer:Q18Lymph nodes of the thorax
Page 91 and 92: Q20Lymph nodes of the abdomen may a
Page 93: Lymph Nodes of Upper and Lower Extr
Page 96 and 97: Answer:Q22c 1. Popliteal Heela 2. A
Page 98 and 99: Hodgkin's disease. The histologic c
Page 100 and 101: Answer:Q23Benign tumors of lymphoid
Page 102 and 103: Extralymphatic/ExtranodalSitesLymph
Page 104 and 105: Answer:Q27Non-Hodgkin's lymphomas m
Page 106 and 107: TilE CARDIOVASCULAR SYSTEMIonatod
Page 108 and 109: CIRCULATORY SYSTEMFigure 14D. BLOOD
Page 110 and 111: Answer:Q1The cardiovascular system
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The heart lies in a loose-fitting s
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106
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Answer:Q5The heart has four chamber
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Answer:QIODeoxygenated blood from t
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Portal System (portal circulation)V
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Answer:QllThe three kinds of blood
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116
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Answer:QlgThe three main types of b
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120
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Answer:Q18White blood cells which a
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DEVELOPMENTOF WHITE BLOOD CELLSStem
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Answer:Q20Malignant diseases of the
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Answer:Q25b 1. Leukemia An uncontro
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130
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132
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Answer:Q1The parts of the respirato
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136
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Answer:Q41. Serves as a passageway
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140
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Answer:Q7The pharynx can be divided
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The larynx can be divided into thre
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146
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Answer:Q10The three single cartilag
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150
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Answer:Q14The windpipe or trachea s
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The lungs provide a place where lar
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Answer:Q16The main bronchus, pulmon
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Clinical ManifestationsClinical man
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Answer:Q19The interpleural space ma
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Answer:Q24_g_ 1. Exchange of oxygen
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DIGESTIVE SYSTEM: Esophagus-RectumP
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The organs of the digestive system
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Answer:Q1The main organs of the dig
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• Lips. The lips form the upper a
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Answer:Q5The lip consists of an exp
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Malignant TumorsMalignant lesions a
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Answer:Q8The tongue is composed of
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• Gums (gingiva). The gums are fo
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Answer:Qllb__ 1. GumMucosal coverin
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182
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Answer:Q12The palate is the roof of
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186
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Answer:Q18The major salivary glands
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190
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Answer:Q21c 1. Gum Retropharyngeala
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Oropharynx. The air and food passag
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196
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Answer:Q23Another name for the hypo
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Answer:Q25a__ 1. HypopharynxServes
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Answer:Q28a. Tonsillar pillar - Oro
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Figure 31. MEASUREMENTS OF THE ESOP
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206
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Answer:Q30The esophagus extends fro
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The medial border of the stomach is
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Q33The stomach lies just below thei
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Answer:Q33The stomach lies just bel
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216
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Answer:Q38The small intestine is ab
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The large intestine receives the fl
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Malignantand Benign TumorsThe usual
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224
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Answer:Q41The large intestine is ab
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Answer:Q433. The ileocolic lymph no
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Metastatic tumors involving the liv
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Answer:Q45The most common primary t
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234
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Answer: 046The function of the gall
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238
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Answer:Q48.The pancreas plays an im
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Figure 39. PRINCIPAL PARTS OF THE U
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The microscopic structure of the re
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Answer:Q1The urinary system consist
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Figure 41. A NEPHRON_ Otomes_JLus_;
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250
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Answer:Q4The blood is circulated th
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254
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Answer:Q8The regional lymph node dr
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258
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Answer:Q12The tube which carries ur
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URINARY BLADDER, RENAL PELVIS AND U
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Malignant TumorsBladder cancer is t
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Answer:Q14The urinary bladder is a
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Q18Theis a membranous tube which co
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Answer:Q18The urethra is a membrano
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Figure 44.FEMALE PELVIS (frontal vi
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CORPUSUTERII I _ 'PRIMARY] ENDOMETR
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Answer:Q1The female reproductiveorg
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• Choriocarcinoma, a highly malig
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Answer:Q6For corpus uteri you might
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FallopiantubesThe fallopian tubes,
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Answer:Q7b 1. Uterus Pear-shaped mu
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Q8Name the three openings of the ut
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Answer: 08In naming the three openi
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Regional Lymph NodesThe regional ly
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6. Vaginal orifice f. Glands that s
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Answer:Q14The vagina is situated be
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296
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298
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Answer:Q19The breasts overlie the p
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A tumor specified as "subareolar" i
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Answer:Q22One of the first and most
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306
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ANSWERS TO REVIEW TESTd 1. Gonads i
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310
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Answer:Q25The male gonads consist o
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314
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Answer:Q27c 1. Epididymis Tube loca
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Figure 51. PROSTATE GLAND (frontal
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Answer:Q29b 1. Prostate Gland which
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RegionalLymph NodesThe regional lym
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324
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Answer:Q30Male hormones are produce
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Figure 53. ENDOCRINEGLANDS328
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• Prolactin (luteotrophic hormone
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Parathyroid GlandThere are four par
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Thymus GlandThe thymus gland is loc
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Q2Match the hormone on the left wit
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Answer:Q1d 1. Hormones Organic secr
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340
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Figure 58.AXIAL SKELETONSkuLl.342
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344
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Answer:Q1The skeletal system is com
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348
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Answer:Q4One characteristic which d
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352
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Answer:Q8The purpose of the sesamoi
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Structure of BoneEach long bone of
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Answer:QllThe numbered parts of the
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Facial bones. The facial bones are
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Figure 65. BONES OF THE THORAX Figu
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Q17Match the bones on the left with
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Figure 67. APPENDICULARSKELETON366
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Malignant TumorsBone is derived fro
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Q20Sites from which metastases to b
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Q22Match the description on the lef
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Answer:Q21c 1. Angiosarcoma A malig
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Figure 68.MUSCLE TYPES376
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Figure 69. HISTOLOGICAL COMPARISONS
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Answer:Q1The three types of muscle
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382
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Answer:Q61. True Malignant tumors o
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• Supinators turn the palm upward
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Answer:Q8The three general function
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Answer:Q11Match the muscle groups o
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392
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Figure 70.NERVE CELL (neuron)394
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Answer:Q1The central nervous system
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Figure 71.CEREBRUMCEREBRUMC_ere_etr
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400
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Figure 74 CRANIAL NERVES402
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MalignantTumorsGliomas are tumors o
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406
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Answer:Q6Match each term on the lef
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410
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412
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Answer:Q1The five major sensesof th
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416
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Answer:Q3The three layers which com
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420
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Answer:Q5The eyeball/s not a solid
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424
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Answer:Q8Name the lymph nodes which
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Figure 80. TONGUE: Areas of tasteUv
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Answer:QllReceptors for the sense o
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Malignant TumorsTumors of the nasal
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Answer:Q13The nasal fossa is divide
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Regional Lymph NodesThe lymphatics
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Answer:Q16b 1. External ear Made up
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440
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HISTOLOGIC TYPE PRIMARY SITELeukemi
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444
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DETERMINATION OF SUBSEQUENT PRIMARI
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Page 462 and 463:
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Page 472 and 473:
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470
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OTHER ICD-O-2 CODES TO BE CONSIDERE
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474
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SELECTED BIBLIOGRAPHY (cont'd)Paul,
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478
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Adenocarcinoma (continued)Primary s
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Arteries (see also Vessels) (contin
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Blood (see also Cardiovascular syst
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Bone tissue (osseous, vascular tiss
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Breast (mammary gland) (continued)H
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Cartilage (nonvascular tissue) (con
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Cerebrum (forebrain, telencephalon)
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Cortisol, 329, 333, 336, 338Cortiso
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Ducts (see also Endocrine system an
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Estradiol, 281Estrogen-producing ca
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Follicular adenocarcinoma, 331, 337
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Glycogen, 229Gonadotrophic hormone
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Histologic type of cancer, 439-441H
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Integumentary system (skin) (contin
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Kidney (see also Urinary system) (c
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Leukocyte (WBC),Agranular, 119B-Cel
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Luteal cell, 281Luteinizing hormone
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Lymph nodes (continued)Perivesical,
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Lymphoma (continued)Nasopharynx (ph
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Metastases (continued)Lymph node, 6
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Muscle (see also Muscular system) (
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Nervous system, Cranial (continued)
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Ovary (female gonad), 273, 281,285,
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Peripheral nervous system, 393, 396
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Prostate (continued)Urethra (prosta
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Salivary gland (see also Parotid, S
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Skull (diploe), 351, 354, 356, 359,
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Sulcus,Buccal, 178Nasolabial, 39Sup
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Tibia (shin bone), 351, 369Tumors o
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Tumor (see also specific histologic
Page 548 and 549:
Urethra (female, male) (continued)L
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Vertebral cavity, 10Vertebral colum
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