TECHNICAL PROGRAM - American Chemical Society Publications

CARB TECHNICAL PROGRAM
8:45 56. Strong and selective molecular recognition
of the DNA minor groove: Compound
and DNA chemistry and unusual
conformational matching. W. Wilson,
R. Nanjunda, A. Kumar, M. Munde, Y. Liu,
R. Hunt, D. W. Boykin
9:25 Intermission
9:35 57. Toward DNA recognition by a Janus
Wedge approach. L. W. McLaughlin,
A. Pal, H. Chen, M. Meena
10:15 58. Recognition of DNA major groove.
D. P. Arya, L. Xue, S. Kumar
10:55 59. Identification and cleavage site
analysis of DNA sequences bound
strongly by bleomycin. S. M. Hecht
Section B
Boston Convention & Exhibition Center
Room 252A
General Papers Glycobiology
T. Lowary, Organizer
E. Cioffi, Presiding
9:00 60. Synthesis and characterization of
chain-end functionalizable glycopolymer
and its oriented glyco-macroligand formation.
S. Narla,X.Sun
9:20 61. Separation and characterization of
the glycosaminoglycan components of
proteoglycans. M. Ly, T. N. Laremore,
K. Solakyildirim, R. J. Linhardt
9:40 62. Synthesis of nucleotide activated Lsugars
from polyols via bioconversion.
R. D. Woodyer
10:00 Intermission
10:15 63. Glycomorphology of the pulmonary
vasculature: Endothelial cell glycocalyx
and endothelial barrier function.
E. Cioffi
10:35 64. Multidimensional glycan arrays for
enhanced lectin and antibody profiling.
Y. Zhang, C. Campbell, Q. Li,
J. Gildersleeve
10:55 65. Peptide nucleic acids bind
strongly and sequence selectively to double
helical RNA. T. T. Zengeya,M.Li,
E. Rozners
11:15 66. Post surface function method for
preparation of liposomal glyco-conjugates.
H. Zhang, Y. Ma, X. Sun
WEDNESDAY AFTERNOON
Section B
Boston Convention & Exhibition Center
Room 252A
General Papers Glycobiology and
Computation
T. Lowary, Organizer
S. Graham, Presiding
1:00 67. Approach to study carbohydratecarbohydrate
interactions involved in myelin
using glycolipids assay in microtiter
plate. J. Zhao,A.Basu
1:20 68. Withdrawn
1:40 69. Synthesis and characterization of
protein glycopolymer conjugate.
V. Gruzdys,X.Sun
2:00 70. Robust analytical development for
oligonucleotide manufacture.
I. Roymoulik
2:20 Intermission
2:35 71. Glycomics studies on central nervous
system. F. Zhang, Z. Liu,
K. Solakyildirim, D. Pu, R. J. Linhardt
2:55 72. Computational studies on the interactions
of mannose with DOPC and
POPC phospholipids. P. R,G.S
3:15 73. Optimizatin of analysis of glycosaminoglycans
in biological samples.
B. Li, R. J. Linhardt
3:35 74. Conformational analysis of nucleosides
and nucleotides: PSEUROT 2010.
S. M. Graham
18–TECH
‡ Cooperative Cosponsorship
Section A
Boston Convention & Exhibition Center
Room 251
Recognition of DNA: Recent Advances
D. Arya, Organizer, Presiding
1:30 75. Role of DNA topography in recognition
by proteins and small molecules.
T. D. Tullius
2:10 76. Selective modulation of DNA polymerase
activity by fixed-conformation nucleoside
analogs. M. Egli, R. L. Eoff,
V. E. Marquez, F. P. Guengerich
2:50 77. Structural mechanisms underlying
DNA replication and human DNA mismatch
repair. L. S. Beese,
E. McSweeney, P. L. Modrich, J. Orans,
Q. Tseng, W. Wang
3:30 Intermission
3:45 78. Manipulating the electrostatic potential
in the DNA grooves: Effect on thermodynamic
stability, ion binding, hydration
and structure. B. Gold
4:25 79. Sequence-dependent recognition
of minor groove width. B. Honig
WEDNESDAY EVENING
Section A
Boston Convention & Exposition Center
Hall C
General Posters
T. Lowary, Organizer
8:00–10:00
80. Glycosylation of substituted 4H-1,2,4triazole-3-thiol.
E. H. El Ashry
81. Expression and characterization of enzymes
for bioenzymatic synthesis of heparin.
P. Paul, W. Zhao, R. Linhardt,
J. Dordick, J. Liu
82. Catalytic conversion of biomass-derived
carbohydrates to useful chemicals in one
step. W. Yang,A.Sen
83. Behaviour of polysaccharide aggregates
in asymmetrical field-flow fractionation
and size-exclusion chromatography.
L. Pitkänen, M. Tenkanen, P. Tuomainen
84. Key new observations in the synthesis of
thiosialosides. I. F. Oliveira, G. R. Morais,
B. R. Springett, R. A. Falconer
85. Synthesis and structural optimization of
antifungal kanamycin B analogs.
M. Y. Fosso, Y. Kawasaki, S. Shrestha,
J. Takemoto, T. C. Chang
86. E. coli K5 heparosan production for bioengineered
heparin. Z. Wang,M.Ly,
F. Zhang, Z. Zhang, J. S. Dordick,
R. J. Linhardt
87. Stochastic simulation of lectin microarrays
with nanosensor transducers: Potential
platforms for optimal, high-throughput
screening and profiling of glycoproteins.
N. F. Reuel, J. Ahn, M. S. Strano
88. Evaluation of different thioesters for glycocluster
synthesis applying native
chemical ligation. J. W. Wehner,
T. K. Lindhorst
89. NMR for structure elucidation of commercially
available heparin polysaccharides.
K. Solakyildirim, S. A. McCallum,
R. J. Linhardt
90. Syntheses of C-5-spirocyclic C-glycoside
SGLT2 inhibitors. B. A. Thuma,
V. Mascitti, R. P. Robinson, C. Préville,
M. R. Reese, R. J. Maguire, C. L. Carr,
M. T. Leininger, A. Lowe, C. M. Steppan
91. Co-axial cellulose nanofibers for electrical
applications. M. Miyauchi, J. Miao,
T. J. Simmons, J. S. Dordick,
R. J. Linhardt
92. Study on the relative reactivity of glycosyl
acceptors in the glycosylations of
2-Azido-2-deoxy-galactosides.
J. Kalikanda,Z.Li
93. Synthesis of tailored glycoconjugates for
the precise detection of pathogens.
A. A. Kulkarni, S. S. Iyer
94. Structure-activity studies of synthetic
glycophosphatidylinositol anchored proteins.
C. V. Christianson,
P. H. Seeberger
95. Chemoenzymatic synthesis of heparan
sulfate. R. Liu, J. Liu, Y. Xu
96. Synthesis of a fluorous-tagged disaccharide
for the enzymatic preparation of heparin
oligosaccharides. S. Masuko,
S. Bera, R. J. Linhardt
97. Preventing the transmission of Plasmodium
falciparum through the inhibition of
malaria protein binding to placental chondroitin
sulfate A. J. M. Beaudet,
L. J. Mansur, B. Yang, F. Zhang,
R. J. Linhardt
98. Real-time assessment of the morphological
change of cellulose in response to
enzymatic treatment. C. Nguyen
99. Chemoselective glycosylation of hemoglobin
as a potential oxygen therapeutic.
T. J. Styslinger, N. Zhang, A. F. Palmer,
P. G. Wang
100. Immobilization of enzymes relevant to
bioengineered heparin synthesis.
E. R. Sterner, R. J. Linhardt,
J. S. Dordick, J. Liu, F. Zhang, W. Zhao,
P. Paul, J. Martin
101. Analyses of anti Tn-antigen MLS128
monoclonal antibody binding to two or
three consecutive Tn-antigen clusters by
surface plasmon resonance (SPR) and
NMR. A. Takasaki-Matsumoto,
S. Hanashima, A. Aoki, Y. Yamaguchi,
R. Sato, H. Kawakami, M. Mizuno,
Y. Fujita-Yamaguchi
102. Modular glycoconjugate tool set for assembly
and presentation of multivalent
carbohydrate ligands on surfaces.
I. Abia, B. Sanders, M. D. Best,
D. C. Baker
103. Analysis of the absorption of low molecular
weight heparin in human umbilical
cord tissue as a model for the prevention
of cancer metastasis. A. M. Weyers,
T. Sudha, B. Yang, B. Li, M. Takieddin,
F. Zhang, S. A. Mousa, R. J. Linhardt
104. Synthesis and biological evaluation of a
Gal(�1-2)GalCer analog. Y. Liang,
A. R. Howell
105. Thiol-click chemistry approach to glycomimetics:
Novel stereoselective synthesis
of (1-3)-S-thiodisaccharides.
Z. J. Witczak, I. Bak-Sypien
106. High-throughput glycoarray for monitoring
immune responses to a cancer
vaccine. C. Campbell,Y.Zhang,
O. Ludek, D. Farnsworth, J. Gildersleeve
107. NMR spectroscopic studies of APF: A
small glycopeptide possessing potent
antiproliferative activity. K. M. Adams,
P. Kaczmarek, S. K. Keay, J. J. Barchi, Jr
108. Structural and quantitative analysis of
disaccharides using CE with LIF detection.
Y. Chang, T. Laremore, F. Zhang,
R. J. Linhardt
109. Development of a novel cancer vaccine
based on multivalent presentation of tumor-associated
carbohydrate antigens
on gold nanoparticle scaffolds.
R. P. Brinas, A. Sundgren, M. Maetani,
O. Abbudayyeh, H. A. Young, M. Sanford,
J. J. Barchi
110. Carbon nanotubes and chitosan as
possible scaffolds for bone tissue regeneration.
J. Stone, Y. Olusanya, W. Jones,
P. Traisawatwong, M. Stewart,
C. Kelly-Brown, L. Carson, A. Oki,
E. C. Regisford
111. Biosynthesis of heparin by metabolic
engineering of Chinese hamster ovary
cells. L. Gasimli, J. Baik, S. Sharfstein,
R. J. Linhardt
112. Purification strategies for separation of
capsular polysaccharide from fermentation
broth. U. Bhaskar,Z.Wang,
F. Zhang, J. S. Dordick, R. J. Linhardt
113. Design, synthesis, and characterization
of sulfated N-aryl aminoglycosides.
A. M. Fenner,R.J.Kerns
114. Photo-click immobilization of carbohydrates
on polymeric surfaces: An effortless
method to functionalize surfaces for
biomolecular recognition studies.
O. Norberg,L.Deng,M.Yan,
O. Ramström
115. On-line microflow high-performance liquid
chromatography with nano-electrospray
ionization mass spectrometry for
heparan sulfate disaccharide analysis.
B. Yang, K. Solakyildirim, J. G. Martin,
T. Laremore, R. J. Linhardt
THURSDAY MORNING
Section A
Boston Convention & Exhibition Center
Room 251
General Papers Synthetic Chemistry
T. Lowary, Organizer
C. Marzabadi, Presiding
8:45 116. De novo synthesis of a 2-acetamido-4-amino-2,4,6-trideoxy-D-galactose
(AAT) building block for the preparation
of the zwitterionic polysaccharide A1
(PS A1) repeating subunit of Bacteroides
fragilis. R. Pragani, P. H. Seeberger
9:05 117. Automated solution-phase synthesis
of alpha-galactosides.
R. Roychoudhury,N.L.Pohl
9:25 118. Study of the protecting group participation
and stereoselectivity of
2-azido-2-deoxygalactopyranosyl donors.
Z. Li
9:45 119. Reactions of glycals with orthosubstituted
benzanilines.
C. H. Marzabadi, K. Kochalski
10:05 120. Novel glycolipids in CD1d-mediated
immunity: Synthesis of new agonists
for CD1d. J. Wojno, J. Jukes, P. Polzella,
V. Cerundolo, L. R. Cox, G. S. Besra
10:25 Intermission
10:40 121. Automated synthesis of systematic
di- and tri-saccharide libraries.
X. Liu, B. Y. Collet, S. Tang,
S. K. Nagappayya, R. Roychoudhury,
X. Li, H. Edwards, N. L. Pohl
11:00 122. Probe of activated glycoside
building block stability for automated solution-phase
synthesis of carbohydrate libraries.
B. Y. Collet, X. Liu, S. Tang,
H. Edwards, S. Nagappayya, L. Liu,
N. L. Pohl
11:20 123. Synthesis of unnatural glycosaminoglycans
and evaluation of their interaction
with proteins. S. Bera
11:40 124. Grafting of cellulose esters by
single electron transfer living radical polymerization
Set-LrP. P. Vlcek,V.Raus,
M. Janata, J. Kriz, P. Latalova, E. Cadova
THURSDAY AFTERNOON
Section A
Boston Convention & Exhibition Center
Room 251
General Papers
Polysaccharides
T. Lowary, Organizer
R. Narain, Presiding
1:00 125. Solvation and hydrolysis of cellulose
with transition metal salts. V. Viner,
B. G. Harvey, R. L. Quintana
1:20 126. Chemical derivatization of glucan
microparticles for targeted delivery.
E. R. Soto, G. R. Ostroff
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