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TECHNICAL PROGRAM - American Chemical Society Publications

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NUCL/ORGN <strong>TECHNICAL</strong> <strong>PROGRAM</strong><br />

2:50 121. Reactor-based fission production<br />

of Molybdenum-99 from LEU solution targets.<br />

M. C. Lagunas-Solar<br />

3:05 Intermission<br />

3:20 122. Subcritical hybrid intense neutron<br />

emitter (SHINE): An innovative method to<br />

produce 99 Mo. G. R. Piefer<br />

3:35 123. 122 Xe/ 122 I Generator development:<br />

Short-lived PET isotope availability.<br />

J. P. O’Neil, T. F. Buddinger<br />

3:50 124. Compact, low-cost radioisotope<br />

production with electromagnetic particle<br />

accelerators. G. B. Rieker,<br />

F. Poehlmann, M. Cappelli<br />

4:05 125. Isotope production for medical<br />

usage Fast neutron reactions in JAEA.<br />

Y. Hatsukawa<br />

4:20 126. Novel nucleosynthesis for medical<br />

isotopes. C. Tahan<br />

4:35 127. Electromagnetic systems for production<br />

of stable isotopes. A. Wong,<br />

G. Paskalov, R. McCaughey, R. Wang,<br />

J. Chen<br />

THURSDAY MORNING<br />

Section B<br />

Boston Convention & Exhibition Center<br />

Room 109B<br />

Aqueous Chemistry and Thermodynamics<br />

of Actinides and Fission Products: A Tribute<br />

to Volker Neck<br />

H. Nitsche, H. Geckeis, T. Fanghänel<br />

(Fanghaenel), Organizers<br />

A. Felmy, M. Altmaier, Presiding<br />

8:00 128. Solubility, surface charge, ion adsorption<br />

and dissolution/precipitation kinetics<br />

of oxides in hydrothermal solutions.<br />

D. J. Wesolowski<br />

8:30 129. Redox transformations of PuO 2�x<br />

induced by Fe(II): Importance of the Fe(III)<br />

reaction product. A. R. Felmy,<br />

S. D. Conradson, E. S. Ilton<br />

9:00 130. Radiation assisted reactions at a<br />

PuO 2 - water interface. A. Seibert,<br />

T. Gouder, F. Huber<br />

9:30 131. Radiation effects on the separation<br />

of technetium-99 by macrocompounds.<br />

A. Roman, K. Campbell,<br />

E. Brown, A. Nunez, a. Espartero,<br />

P. Paviet-Hartmann<br />

9:50 132. Withdrawn<br />

10:10 133. Nitric acid radiation effects on<br />

solvent extraction chemistry.<br />

T. D. Cullen, S. P. Mezyk, G. Elias,<br />

B. J. Mincher<br />

10:30 Intermission<br />

10:45 134. Some reflections and thoughts<br />

after 25 years developing thermodynamic<br />

data bases for nuclear waste management<br />

and other environmental applications.<br />

J. Bruno,L.Duro<br />

11:15 135. THEREDA: The thermodynamic<br />

reference database for nuclear waste disposal<br />

in Germany. H. C. Moog,<br />

H. Herbert, V. Brendler, A. Richter,<br />

M. Altmaier, C. Marquardt, W. Voigt,<br />

S. Wilhelm<br />

11:35 136. Investigation of the radiolytic stability<br />

of DTPA under TALSPEAK conditions.<br />

D. K. Gaskins, S. P. Mezyk,<br />

L. R. Martin<br />

11:55 137. Mixed-ligands complexes of<br />

trivalent Am 3� ,Cm 3� and Eu 3� with<br />

HEDTA�NTA-complexation thermodynamics<br />

and structural aspects.<br />

P. Thakur, G. R. Choppin, J. L. Conca<br />

12:15 Concluding Remarks<br />

84–TECH<br />

‡ Cooperative Cosponsorship<br />

Section A<br />

Boston Convention & Exhibition Center<br />

Room 109A<br />

Applications of Radionuclides in Imaging<br />

and Therapy<br />

Multimodality, Therapy, and Other<br />

A. Packard, M. Lewis, Organizers,<br />

Presiding<br />

9:00 138. Multimodal imaging probes for fibrin.<br />

R. Uppal, P. Caravan<br />

9:20 139. Radiolabeled Sonic Hedgehog as<br />

a ligand targeting cancer stem cells.<br />

I. Tworowska, J. Sims-Mourtada<br />

9:40 140. Selection of small pretargeting<br />

molecules with affinity for radiochelates.<br />

N. Sisay, S. S. Jurisson, G. P. Smith<br />

10:00 Intermission<br />

10:15 141. In vitro and in vivo evaluations of<br />

177 Lu antisense radiotherapy in B-cell<br />

non-Hodgkin’s lymphoma. E. R. Balkin,<br />

F. Jia, W. H. Miller, M. R. Lewis<br />

10:35 142. Radioiodinated maleimide derivatives<br />

targeting peripheral and membrane<br />

sulfhydryl groups for in vitro cell labeling.<br />

J. K. Amartey<br />

10:55 143. Successful multimodality nuclear<br />

and fluorescent tumor imaging in mice<br />

using a streptavidin nanoparticle.<br />

d. j. hnatowich, M. Liang, X. Liu,<br />

D. Cheng, G. Liu, S. Dou, Y. Wang,<br />

M. Rusckowski<br />

THURSDAY AFTERNOON<br />

Section A<br />

Boston Convention & Exhibition Center<br />

Room 109A<br />

Applications of Radionuclides in Imaging<br />

and Therapy<br />

Radiometals: Imaging<br />

A. Packard, M. Lewis, Organizers,<br />

Presiding<br />

1:00 144. Radiolabeled peptides for PET imaging:<br />

The impact of the bifunctional chelator.<br />

C. L. Ferreira, D. T. Yapp, R. Gill,<br />

C. Bensimon, P. Jurek, G. Kiefer<br />

1:20 145. microPET imaging of integrin � 2� 1<br />

expression using 64 Cu-labeled DGEA<br />

peptides. C. Huang, Z. Li,H.Cai,<br />

K. Chen, R. Park, T. Shahinian,<br />

P. S. Conti<br />

1:40 146. Comparative study of 64 Cu and<br />

67 Ga-bombesin antagonists as potential<br />

agents for prostate cancer imaging.<br />

P. K. Nanda, U. Pandey, B. N. Bottenus,<br />

S. R. Lane, T. L. Rold, G. L. Sieckman,<br />

T. J. Hoffman, C. J. Smith<br />

2:00 Intermission<br />

2:20 147. Highly stable functionalizable chelator<br />

for gallium isotopes. E. Boros,<br />

C. L. Ferreira, J. F. Cawthray, E. W. Price,<br />

D. W. Wester, M. J. Adam, C. Orvig<br />

2:40 148. Human islet cell imaging in mice<br />

by pretargeting using a DNA analog<br />

(MORF) conjugated antibody and a radiolabeled<br />

cMORF. G. Liu,S.Dou,<br />

D. Cheng, J. Leif, M. Rusckowski,<br />

P. Streeter, L. D. Shultz, D. L. Greiner,<br />

D. J. Hnatowich<br />

3:00 149. Targeting the prostate specific<br />

membrane antigen in prostate cancer<br />

with Tc-99m phosphoramidate inhibitors.<br />

P. D. Benny, J. Byers, M. Jabbes,<br />

C. Berkman, J. N. Bryan<br />

3:20 150. One-pot synthesis of trifunctional<br />

Tc-99m radioconjugates by click chemistry.<br />

T. L. Mindt, H. Struthers, B. Spingler,<br />

E. Garcia-Garayoa, D. Tourwé, R. Schibli<br />

ORGN<br />

Division of Organic<br />

Chemistry<br />

A. Abdel-Magid and S. Sieburth,<br />

Program Chairs<br />

OTHER SYMPOSIA OF INTEREST:<br />

Academic Employment Initiative (see<br />

AEI, Mon)<br />

Synthetic Chemistry for Biological<br />

Imaging, Quantitation, and Discovery<br />

(see BIOL, Sun)<br />

Natural Products Biosynthesis (see<br />

BIOL, Tue)<br />

Advances in Teaching Organic<br />

Chemistry (see CHED, Tue)<br />

Chemistry and Policy: Solving<br />

Problems at the Interface (see CHED,<br />

Mon)<br />

Undergraduate Research Posters:<br />

Organic Chemistry (see CHED, Mon)<br />

SOCIAL EVENTS:<br />

Social Hour, 8:00 PM: Sun<br />

Organic & Medicinal Chemistry<br />

Divisions Joint Poster Session &<br />

Social Event, 7:00 PM: Wed<br />

Tetrahedron Award Reception, 5:30<br />

PM: Mon<br />

Arthur C. Cope Award & Arthur C.<br />

Cope Scholars’ Awards Reception,<br />

5:30 PM: Tue<br />

BUSINESS MEETING:<br />

Business Meeting, 5:00 PM: Sun<br />

SUNDAY MORNING<br />

Section C<br />

Boston Convention & Exhibition Center<br />

Room 206A<br />

New Reactions and Methodology<br />

S. Sieburth, Organizer<br />

L. Anderson, Presiding<br />

8:00 1. Hydroxyl group directed copper/<br />

selectfluor-activated C-H bond amination.<br />

Z. Jin, J. C. Aponte, B. Xu,<br />

G. B. Hammond<br />

8:20 2. Recent advances in organic synthesis<br />

using real-time in situ FTIR (fourier<br />

transform infrared spectroscopy).<br />

D. Hebrault<br />

8:40 3. Multidimensional screening and<br />

methodology development of condensations<br />

involving complex 1,2-diketones.<br />

J. R. Goodell, A. B. Beeler, J. A. Porco,<br />

Jr.<br />

9:00 4. Water overcomes methyl group directing<br />

effects in endo-selective epoxideopening<br />

cascades. C. J. Morten,<br />

T. F. Jamison<br />

9:20 5. Preactivated unsymmetrical diboron:<br />

Catalytic regioselective boration of �,�unsaturated<br />

conjugated compounds.<br />

W. L. Santos,G.Ming,S.B.Thorpe<br />

9:40 6. TEMPO-coated Fe 3O 4 superparamagnetic<br />

nanoparticles: A recyclable catalyst<br />

for selective oxidation of alcohols.<br />

A. K. Tucker-Schwartz, R. L. Garrell<br />

10:00 7. N-triflylphosphoramides: From synthesis<br />

and applications in organocatalysis<br />

towards combined metal-Brønsted acid<br />

catalysis. R. M. Koenigs, M. Rueping<br />

10:20 8. C-H bonds as ubiquitous functionality:<br />

A general approach to complex imidazoles<br />

via regioselective sequential<br />

arylation of all three C-H bonds and regioselective<br />

N-alkylation of SEM-imidazoles.<br />

J. Joo, B. Touré, D. Sames<br />

10:40 9. Halogenation of hydrocarbon substrates<br />

with peracetic acid and halide<br />

salts. Y. He, C. R. Goldsmith<br />

11:00 10. Oxidative coupling reactions: New<br />

methods for the synthesis of carbogenic<br />

molecules. L. C. Konkol,R.J.Thomson<br />

11:20 11. Metal-free syn-dihydroxylation of<br />

alkenes. S. Picon,N.C.Tomkinson<br />

11:40 12. Greater than 99% site-isolation of<br />

phosphines and Pd using polydicyclopentadiene<br />

membranes. A. Gupta,<br />

N. B. Bowden<br />

12:00 13. Using catalytic scaffolding ligands<br />

for regio- and enantioselective hydroformylation.<br />

A. Worthy,C.Joe,K.Tan<br />

Section D<br />

Boston Convention & Exhibition Center<br />

Room 203<br />

Peptides, Proteins and Amino Acids<br />

S. Sieburth, Organizer<br />

J. Gao, Presiding<br />

8:00 14. Iterative elongation of small peptides<br />

for developing capture agents via<br />

reliable screening. J. Lim, J. Cha, S. Tan,<br />

Y. Zheng, Y. Ang, S. Lee<br />

8:20 15. Lanthanide sensitization and fluorescent<br />

sensing of A/T-rich DNA sequences<br />

and oncogenic bZIP transcription<br />

factors. E. Pazos, M. I. Sánchez,<br />

J. Mosquera, C. Penas, J. L. Mascareñas,<br />

M. Vázquez<br />

8:40 16. High throughput screening of cyclic<br />

peptides library to identify inhibitors<br />

against calcineurin/NFAT interaction.<br />

T. Liu,D.Pei<br />

9:00 17. Use of triazole-stapled BCL9/B9L<br />

�-helical peptides to target �-catenin and<br />

inhibit Wnt signaling. S. A. Kawamoto,<br />

A. Coleska, X. Ran, H. Yi, C. Yang,<br />

S. Wang<br />

9:20 18. Peptide-surface interactions.<br />

J. L. Kulp III, K. P. Fears,<br />

D. Y. Petrovykh, T. D. Clark<br />

9:40 19. Rationally designed cyclic sulfopeptides<br />

for HIV-1 entry inhibition.<br />

J. G. Rudick, M. M. Laakso, R. W. Doms,<br />

W. F. DeGrado<br />

10:00 20. Translocating membrane-impermeable<br />

toxins into cancer cells: pHLIPmediated<br />

delivery of phalloidin inhibits<br />

cell proliferation. M. An, D. Wijesinghe,<br />

O. A. Andreev, Y. K. Reshetnyak,<br />

D. M. Engelman<br />

10:20 21. Evolved aminoacyl-tRNA synthetases<br />

with unusual polyspecificities.<br />

D. D. Young, T. S. Young, I. Ahmad,<br />

P. G. Schultz<br />

10:40 22. Using NMR to characterize small<br />

selectively thionated pseudopeptides.<br />

W. M. Vizcaino, S. M. Schelble<br />

11:00 23. Application of thioacids in the<br />

chemical ligation of peptides. I. Sharma,<br />

D. Crich<br />

11:20 24. Formation of the 5,6-dihydrouridin-6-yl<br />

radical in RNA results in direct<br />

strand scission. M. J. Resendiz,<br />

A. C. Jacobs, M. M. Greenberg*<br />

11:40 25. Studying peptide aggregation with<br />

a series of phosphopeptide variants.<br />

N. M. Valette, S. E. Radford, S. A. Harris,<br />

S. L. Warriner<br />

Photographing or recording<br />

meeting sessions and/or<br />

activities other than your own<br />

are prohibited at all official<br />

ACS events without written<br />

consent from ACS.

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