TECHNICAL PROGRAM - American Chemical Society Publications
TECHNICAL PROGRAM - American Chemical Society Publications
TECHNICAL PROGRAM - American Chemical Society Publications
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NUCL/ORGN <strong>TECHNICAL</strong> <strong>PROGRAM</strong><br />
2:50 121. Reactor-based fission production<br />
of Molybdenum-99 from LEU solution targets.<br />
M. C. Lagunas-Solar<br />
3:05 Intermission<br />
3:20 122. Subcritical hybrid intense neutron<br />
emitter (SHINE): An innovative method to<br />
produce 99 Mo. G. R. Piefer<br />
3:35 123. 122 Xe/ 122 I Generator development:<br />
Short-lived PET isotope availability.<br />
J. P. O’Neil, T. F. Buddinger<br />
3:50 124. Compact, low-cost radioisotope<br />
production with electromagnetic particle<br />
accelerators. G. B. Rieker,<br />
F. Poehlmann, M. Cappelli<br />
4:05 125. Isotope production for medical<br />
usage Fast neutron reactions in JAEA.<br />
Y. Hatsukawa<br />
4:20 126. Novel nucleosynthesis for medical<br />
isotopes. C. Tahan<br />
4:35 127. Electromagnetic systems for production<br />
of stable isotopes. A. Wong,<br />
G. Paskalov, R. McCaughey, R. Wang,<br />
J. Chen<br />
THURSDAY MORNING<br />
Section B<br />
Boston Convention & Exhibition Center<br />
Room 109B<br />
Aqueous Chemistry and Thermodynamics<br />
of Actinides and Fission Products: A Tribute<br />
to Volker Neck<br />
H. Nitsche, H. Geckeis, T. Fanghänel<br />
(Fanghaenel), Organizers<br />
A. Felmy, M. Altmaier, Presiding<br />
8:00 128. Solubility, surface charge, ion adsorption<br />
and dissolution/precipitation kinetics<br />
of oxides in hydrothermal solutions.<br />
D. J. Wesolowski<br />
8:30 129. Redox transformations of PuO 2�x<br />
induced by Fe(II): Importance of the Fe(III)<br />
reaction product. A. R. Felmy,<br />
S. D. Conradson, E. S. Ilton<br />
9:00 130. Radiation assisted reactions at a<br />
PuO 2 - water interface. A. Seibert,<br />
T. Gouder, F. Huber<br />
9:30 131. Radiation effects on the separation<br />
of technetium-99 by macrocompounds.<br />
A. Roman, K. Campbell,<br />
E. Brown, A. Nunez, a. Espartero,<br />
P. Paviet-Hartmann<br />
9:50 132. Withdrawn<br />
10:10 133. Nitric acid radiation effects on<br />
solvent extraction chemistry.<br />
T. D. Cullen, S. P. Mezyk, G. Elias,<br />
B. J. Mincher<br />
10:30 Intermission<br />
10:45 134. Some reflections and thoughts<br />
after 25 years developing thermodynamic<br />
data bases for nuclear waste management<br />
and other environmental applications.<br />
J. Bruno,L.Duro<br />
11:15 135. THEREDA: The thermodynamic<br />
reference database for nuclear waste disposal<br />
in Germany. H. C. Moog,<br />
H. Herbert, V. Brendler, A. Richter,<br />
M. Altmaier, C. Marquardt, W. Voigt,<br />
S. Wilhelm<br />
11:35 136. Investigation of the radiolytic stability<br />
of DTPA under TALSPEAK conditions.<br />
D. K. Gaskins, S. P. Mezyk,<br />
L. R. Martin<br />
11:55 137. Mixed-ligands complexes of<br />
trivalent Am 3� ,Cm 3� and Eu 3� with<br />
HEDTA�NTA-complexation thermodynamics<br />
and structural aspects.<br />
P. Thakur, G. R. Choppin, J. L. Conca<br />
12:15 Concluding Remarks<br />
84–TECH<br />
‡ Cooperative Cosponsorship<br />
Section A<br />
Boston Convention & Exhibition Center<br />
Room 109A<br />
Applications of Radionuclides in Imaging<br />
and Therapy<br />
Multimodality, Therapy, and Other<br />
A. Packard, M. Lewis, Organizers,<br />
Presiding<br />
9:00 138. Multimodal imaging probes for fibrin.<br />
R. Uppal, P. Caravan<br />
9:20 139. Radiolabeled Sonic Hedgehog as<br />
a ligand targeting cancer stem cells.<br />
I. Tworowska, J. Sims-Mourtada<br />
9:40 140. Selection of small pretargeting<br />
molecules with affinity for radiochelates.<br />
N. Sisay, S. S. Jurisson, G. P. Smith<br />
10:00 Intermission<br />
10:15 141. In vitro and in vivo evaluations of<br />
177 Lu antisense radiotherapy in B-cell<br />
non-Hodgkin’s lymphoma. E. R. Balkin,<br />
F. Jia, W. H. Miller, M. R. Lewis<br />
10:35 142. Radioiodinated maleimide derivatives<br />
targeting peripheral and membrane<br />
sulfhydryl groups for in vitro cell labeling.<br />
J. K. Amartey<br />
10:55 143. Successful multimodality nuclear<br />
and fluorescent tumor imaging in mice<br />
using a streptavidin nanoparticle.<br />
d. j. hnatowich, M. Liang, X. Liu,<br />
D. Cheng, G. Liu, S. Dou, Y. Wang,<br />
M. Rusckowski<br />
THURSDAY AFTERNOON<br />
Section A<br />
Boston Convention & Exhibition Center<br />
Room 109A<br />
Applications of Radionuclides in Imaging<br />
and Therapy<br />
Radiometals: Imaging<br />
A. Packard, M. Lewis, Organizers,<br />
Presiding<br />
1:00 144. Radiolabeled peptides for PET imaging:<br />
The impact of the bifunctional chelator.<br />
C. L. Ferreira, D. T. Yapp, R. Gill,<br />
C. Bensimon, P. Jurek, G. Kiefer<br />
1:20 145. microPET imaging of integrin � 2� 1<br />
expression using 64 Cu-labeled DGEA<br />
peptides. C. Huang, Z. Li,H.Cai,<br />
K. Chen, R. Park, T. Shahinian,<br />
P. S. Conti<br />
1:40 146. Comparative study of 64 Cu and<br />
67 Ga-bombesin antagonists as potential<br />
agents for prostate cancer imaging.<br />
P. K. Nanda, U. Pandey, B. N. Bottenus,<br />
S. R. Lane, T. L. Rold, G. L. Sieckman,<br />
T. J. Hoffman, C. J. Smith<br />
2:00 Intermission<br />
2:20 147. Highly stable functionalizable chelator<br />
for gallium isotopes. E. Boros,<br />
C. L. Ferreira, J. F. Cawthray, E. W. Price,<br />
D. W. Wester, M. J. Adam, C. Orvig<br />
2:40 148. Human islet cell imaging in mice<br />
by pretargeting using a DNA analog<br />
(MORF) conjugated antibody and a radiolabeled<br />
cMORF. G. Liu,S.Dou,<br />
D. Cheng, J. Leif, M. Rusckowski,<br />
P. Streeter, L. D. Shultz, D. L. Greiner,<br />
D. J. Hnatowich<br />
3:00 149. Targeting the prostate specific<br />
membrane antigen in prostate cancer<br />
with Tc-99m phosphoramidate inhibitors.<br />
P. D. Benny, J. Byers, M. Jabbes,<br />
C. Berkman, J. N. Bryan<br />
3:20 150. One-pot synthesis of trifunctional<br />
Tc-99m radioconjugates by click chemistry.<br />
T. L. Mindt, H. Struthers, B. Spingler,<br />
E. Garcia-Garayoa, D. Tourwé, R. Schibli<br />
ORGN<br />
Division of Organic<br />
Chemistry<br />
A. Abdel-Magid and S. Sieburth,<br />
Program Chairs<br />
OTHER SYMPOSIA OF INTEREST:<br />
Academic Employment Initiative (see<br />
AEI, Mon)<br />
Synthetic Chemistry for Biological<br />
Imaging, Quantitation, and Discovery<br />
(see BIOL, Sun)<br />
Natural Products Biosynthesis (see<br />
BIOL, Tue)<br />
Advances in Teaching Organic<br />
Chemistry (see CHED, Tue)<br />
Chemistry and Policy: Solving<br />
Problems at the Interface (see CHED,<br />
Mon)<br />
Undergraduate Research Posters:<br />
Organic Chemistry (see CHED, Mon)<br />
SOCIAL EVENTS:<br />
Social Hour, 8:00 PM: Sun<br />
Organic & Medicinal Chemistry<br />
Divisions Joint Poster Session &<br />
Social Event, 7:00 PM: Wed<br />
Tetrahedron Award Reception, 5:30<br />
PM: Mon<br />
Arthur C. Cope Award & Arthur C.<br />
Cope Scholars’ Awards Reception,<br />
5:30 PM: Tue<br />
BUSINESS MEETING:<br />
Business Meeting, 5:00 PM: Sun<br />
SUNDAY MORNING<br />
Section C<br />
Boston Convention & Exhibition Center<br />
Room 206A<br />
New Reactions and Methodology<br />
S. Sieburth, Organizer<br />
L. Anderson, Presiding<br />
8:00 1. Hydroxyl group directed copper/<br />
selectfluor-activated C-H bond amination.<br />
Z. Jin, J. C. Aponte, B. Xu,<br />
G. B. Hammond<br />
8:20 2. Recent advances in organic synthesis<br />
using real-time in situ FTIR (fourier<br />
transform infrared spectroscopy).<br />
D. Hebrault<br />
8:40 3. Multidimensional screening and<br />
methodology development of condensations<br />
involving complex 1,2-diketones.<br />
J. R. Goodell, A. B. Beeler, J. A. Porco,<br />
Jr.<br />
9:00 4. Water overcomes methyl group directing<br />
effects in endo-selective epoxideopening<br />
cascades. C. J. Morten,<br />
T. F. Jamison<br />
9:20 5. Preactivated unsymmetrical diboron:<br />
Catalytic regioselective boration of �,�unsaturated<br />
conjugated compounds.<br />
W. L. Santos,G.Ming,S.B.Thorpe<br />
9:40 6. TEMPO-coated Fe 3O 4 superparamagnetic<br />
nanoparticles: A recyclable catalyst<br />
for selective oxidation of alcohols.<br />
A. K. Tucker-Schwartz, R. L. Garrell<br />
10:00 7. N-triflylphosphoramides: From synthesis<br />
and applications in organocatalysis<br />
towards combined metal-Brønsted acid<br />
catalysis. R. M. Koenigs, M. Rueping<br />
10:20 8. C-H bonds as ubiquitous functionality:<br />
A general approach to complex imidazoles<br />
via regioselective sequential<br />
arylation of all three C-H bonds and regioselective<br />
N-alkylation of SEM-imidazoles.<br />
J. Joo, B. Touré, D. Sames<br />
10:40 9. Halogenation of hydrocarbon substrates<br />
with peracetic acid and halide<br />
salts. Y. He, C. R. Goldsmith<br />
11:00 10. Oxidative coupling reactions: New<br />
methods for the synthesis of carbogenic<br />
molecules. L. C. Konkol,R.J.Thomson<br />
11:20 11. Metal-free syn-dihydroxylation of<br />
alkenes. S. Picon,N.C.Tomkinson<br />
11:40 12. Greater than 99% site-isolation of<br />
phosphines and Pd using polydicyclopentadiene<br />
membranes. A. Gupta,<br />
N. B. Bowden<br />
12:00 13. Using catalytic scaffolding ligands<br />
for regio- and enantioselective hydroformylation.<br />
A. Worthy,C.Joe,K.Tan<br />
Section D<br />
Boston Convention & Exhibition Center<br />
Room 203<br />
Peptides, Proteins and Amino Acids<br />
S. Sieburth, Organizer<br />
J. Gao, Presiding<br />
8:00 14. Iterative elongation of small peptides<br />
for developing capture agents via<br />
reliable screening. J. Lim, J. Cha, S. Tan,<br />
Y. Zheng, Y. Ang, S. Lee<br />
8:20 15. Lanthanide sensitization and fluorescent<br />
sensing of A/T-rich DNA sequences<br />
and oncogenic bZIP transcription<br />
factors. E. Pazos, M. I. Sánchez,<br />
J. Mosquera, C. Penas, J. L. Mascareñas,<br />
M. Vázquez<br />
8:40 16. High throughput screening of cyclic<br />
peptides library to identify inhibitors<br />
against calcineurin/NFAT interaction.<br />
T. Liu,D.Pei<br />
9:00 17. Use of triazole-stapled BCL9/B9L<br />
�-helical peptides to target �-catenin and<br />
inhibit Wnt signaling. S. A. Kawamoto,<br />
A. Coleska, X. Ran, H. Yi, C. Yang,<br />
S. Wang<br />
9:20 18. Peptide-surface interactions.<br />
J. L. Kulp III, K. P. Fears,<br />
D. Y. Petrovykh, T. D. Clark<br />
9:40 19. Rationally designed cyclic sulfopeptides<br />
for HIV-1 entry inhibition.<br />
J. G. Rudick, M. M. Laakso, R. W. Doms,<br />
W. F. DeGrado<br />
10:00 20. Translocating membrane-impermeable<br />
toxins into cancer cells: pHLIPmediated<br />
delivery of phalloidin inhibits<br />
cell proliferation. M. An, D. Wijesinghe,<br />
O. A. Andreev, Y. K. Reshetnyak,<br />
D. M. Engelman<br />
10:20 21. Evolved aminoacyl-tRNA synthetases<br />
with unusual polyspecificities.<br />
D. D. Young, T. S. Young, I. Ahmad,<br />
P. G. Schultz<br />
10:40 22. Using NMR to characterize small<br />
selectively thionated pseudopeptides.<br />
W. M. Vizcaino, S. M. Schelble<br />
11:00 23. Application of thioacids in the<br />
chemical ligation of peptides. I. Sharma,<br />
D. Crich<br />
11:20 24. Formation of the 5,6-dihydrouridin-6-yl<br />
radical in RNA results in direct<br />
strand scission. M. J. Resendiz,<br />
A. C. Jacobs, M. M. Greenberg*<br />
11:40 25. Studying peptide aggregation with<br />
a series of phosphopeptide variants.<br />
N. M. Valette, S. E. Radford, S. A. Harris,<br />
S. L. Warriner<br />
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