TECHNICAL PROGRAM - American Chemical Society Publications

11:20 816. Calcium dependent self-assembly
of liposomes based on a disaccharide
from the red beard marine sponge.
D. Yüksel, B. Lorenz,
L. Álvarez de Cienfuegos, V. Kalsani,
A. Janshoff, K. Kumar
11:40 817. Identifying structure-property relationships
using pyridine-based molecular
gels. J. Chen,A.J.McNeil
12:00 818. Noncovalent polymer assembly
in water and their applications in materials
fabrication. Y. Y. Luk, L. Wu, J. Lal,
K. A. Simon, E. A. Burton
Section F
Boston Convention & Exhibition Center
Room 204B
Metal-Mediated Reactions and Syntheses
S. Sieburth, Organizer
J. Miranda, Presiding
8:00 819. Preparation of novel 4-aryl- and
4-alkyl-2-silyl-1,3-dienes and their use in
tandem Diels–Alder/Hiyama cross-coupling
reactions. C. S. Junker,
M. E. Welker
8:20 820. Investigating the reactivity of benzylic
nitriles in palladium-catalyzed cross
coupling reactions. M. C. Brannock,
C. B. Gorman
8:40 821. Palladium-catalyzed functionalization
of olefins under oxidative conditions.
N. Selander,K.J.Szabó
9:00 822. Soluble polyethylene oligomers as
supports for NHC ligands. C. Hobbs,
D. E. Bergbreiter, H. S. Bazzi
9:20 823. [2�2] vs. [4�2]: Mechanistic study
on gold-catalyzed oxygen transfer of
alkynyldiketones and alkynylketoesters.
L. Liu, D. Malhotra, G. B. Hammond
9:40 824. Palladium-catalyzed trifluoromethylation
of aryl chlorides and vinyl
sulfonates. E. Cho, T. Senecal, T. Kinzel,
Y. Zhang, S. L. Buchwald
10:00 825. Synthesis of microstegiol, a rearranged
abietane. R. A. Taj, J. R. Green
10:20 826. Regio- and stereoselective
umpolung piperidine synthesis incorporating
�-basic tungsten. D. P. Harrison,
V. E. Zottig, S. Wang, M. Sabat,
W. H. Myers, W. D. Harman
10:40 827. Highly efficient palladium/copper
cocatalytic system for direct arylation of
heteroarenes: The unexpected effect of
Cu(Xantphos)I. J. Huang,J.Chan,
Y. Chen, C. J. Borths, K. D. Baucom,
R. D. Larsen, M. M. Faul
11:00 828. Allylic oxidations of disubstituted
olefins. C. T. Check, W. H. Henderson,
M. J. Vanden Eynden, J. P. Stambuli
11:20 829. Reactivity and properites of dihapto-coordinated
phenols. V. E. Zottig
11:40 830. Oxidant-controlled regioselectivity
in the oxidative arylation of N-acetylindoles
and N-alkylindoles. S. Potavathri,
B. Deboef
Section G
Boston Convention & Exhibition Center
Room 207
Material, Devices and Switches
S. Sieburth, Organizer
R. Smith, Presiding
8:00 831. Luminescent diphosphine coordination
polymers with fluorene and phenylene
ethynylene chromophores.
T. Maltais,R.C.Smith
8:20 832. Soft and deformable gold nanoparticles
with unique conducting properties.
X. Yu, K. Du, C. Versek, D. Patra,
O. R. Miranda, A. D. Dinsmore,
M. T. Tuominen, V. M. Rotello
8:40 833. Walking transition metal complexes.
D. M. D’Souza, R. Carrillo,
B. A. Blight, J. E. Beves, M. Papmeyer,
D. Howgego, D. A. Leigh
9:00 834. Improving the yield of working
tunnel junctions (Ag TS /SAM//oxide/
EGaIn) through near-surface effects on
the SAM. M. T. Mwangi,W.Reus,
C. Kim, M. D. Schulz, G. M. Whitesides
9:20 835. Intracellular delivery of macromolecular
cargo. S. Tarakkad Krishnaji,
V. Kalsani, K. Kumar
9:40 836. Chemical synthesis on SU-8.
K. Qvortrup, K. Taveras, T. E. Nielsen,
O. Thastrup, H. Morgan, S. Birtwell,
G. R. Broder, P. Roach
10:00 837. Facile syntheses of low band
�-conjugated copolymers based on
fused terthiophene and benzothiadiazole.
S. Ku, N. Treat, C. J. Hawker
10:20 838. Combining molecular switches
and quantum dots to create fluorescent
sensors. E. R. Kay, A. B. Greytak,
D. G. Nocera, M. G. Bawendi
10:40 839. Synthesis of carbon nanotubes
of discrete chirality. X. Tian, R. Jasti
11:00 840. Optimization of lumo levels in
low bandgap organic photovoltaic donor
materials through terpolymerization.
R. C. Coffin, C. M. MacNeill, R. E. Noftle,
D. L. Carroll
11:20 841. Synthesis and photochromism of
a unique photoresponive spiro-oxazine
dimer. D. L. Watkins, T. Fujiwara
11:40 842. Helical folding of C 3-symmetric
molecules: Substituent effects on chiral
conformation and exciton-coupled circular
dichroism. E. A. Opsitnick, X. Jiang,
D. Lee
12:00 843. Signal-responsive plastics.
S. T. Phillips
Section B
Boston Convention & Exhibition Center
Room 205A/B
Process Chemistry: Role of Organic
Chemistry in Early Clinical Drug
Development V Cosponsored by MEDI ‡
A. Abdel-Magid, Organizer
J. Pesti, Organizer, Presiding
8:30 Introductory Remarks
8:35 844. Timely chemical process research
is a critical part for efficient drug development.
C. Senanayake
9:15 845. Regioselective synthesis of 1,3,5trisubsituted
pyrazoles via 1,3-dipolar cycloaddition
reactions. L. M. Oh,
G. P. Spoors, H. Wang, S. Shilcrat,
R. Hermann, J. Sisko
9:55 846. Process development of palladium-catalyzed
decarboxylative cross-coupling
of arene carboxylic acids and aryl
bromides. D. Mitchell
10:35 847. Development of a scalable synthesis
of sulopenem: A �-lactam antibacterial
candidate. J. D. Nelson
11:15 848. Stereoselective synthesis of an
all-cis 1,2,3-trisubstituted cyclopropane
carboxylic acid. S. Kiau,
F. Gonzales-Bobes, M. D. Fenster,
S. Kolotuchin, L. Kolla
11:55 Concluding Remarks
WEDNESDAY AFTERNOON
Section B
Boston Convention & Exhibition Center
Room 205A/B
Nanoscaled Materials for Drug Delivery and
Diagnostic Applications
J. Yang, N. Gianneschi, H. Havel,
Organizers, Presiding
1:00 849. Nanoskiving as a route to small
structures. G. M. Whitesides, D. Lipomi,
Q. Xu, R. Rioux, M. Dickey
1:30 850. nab Technology: Tumor targeting
through natural albumin transport via
gp60, caveolin-1, and SPARC. N. Desai
1:55 851. Nanoscale ratiometric dosing formulations
for anticancer combination
chemotherapy. L. D. Mayer
2:20 852. Designed collagen peptide materials
for tissue engineering.
J. Chmielewski
2:45 853. Chemically modified viral capsids
as targeted platforms for diagnostic imaging
and drug delivery. M. B. Francis
3:10 Intermission
3:15 854. Cooperative nanomaterials to
sensitize, target, image, and treat tumors.
M. J. Sailor,J.Park,L.Gu,
G. von Maltzahn, S. N. Bhatia,
E. Ruoslahti
3:45 855. Programming nanoscale materials
with peptides, enzymes and DNA.
N. C. Gianneschi, M. Chien,
M. P. Thompson, T. Ku, L. M. Randolph,
A. M. Rush
4:05 856. Nanoparticle-based delivery of
siRNA. D. E. Levy, B. Frederick, Z. Ding,
B. Luo, S. Zalipsky
4:30 857. Oligonuceolotide-gold nanoparticles
conjugates as intracellular gene
regulation agents. C. A. Mirkin
Section C
Boston Convention & Exhibition Center
Room 206A
New Reactions and Methodology
S. Sieburth, Organizer
A. Mattson, Presiding
1:00 858. Seebach’s conjunctive reagent
enables double cyclizations.
B. D. Chandler, J. T. Roland,
E. J. Sorensen
1:20 859. New methods for C–C, C–O, and
C–N bond formation. P. J. Walsh
1:40 860. Sequential semipinacol-Beckmann
rearrangements for the construction
of 1-azaspirocycles. L. K. Sharma,
G. I. Elliott
2:00 861. Base- and ligand-free copper catalysis
for the alkynylation of imines.
C. H. Larsen, C. E. Meyet, C. J. Pierce
2:20 862. Microwave-assisted domino [3,3]sigmatropic
rearrangement of allylic
azides and Overman rearrangements.
A. A. Tjeng, R. Batey
2:40 863. Palladium(II)-catalyzed dehydrogenative
olefination of cyclic enaminones
via oxidative Heck reaction. Y. Yu,
M. J. Niphakis, G. I. Georg
3:00 864. Synthesis of macrocyclic depsipeptides
by cyclodimerization of amino
esters and lactones. S. Kalidindi,
A. B. Beeler, J. A. Porco
3:20 865. Three step route to polycyclic 2,5dihydropyrroles
from �-silyloxy ketones.
M. Brewer, C. Draghici, Q. Huang
3:40 866. Development of novel hetero
Diels-Alder cycloaddition methodology
for the total synthesis of cyclic guanidine
alkaloids. M. Yu, V. Kumbam,
S. Rasapalli
4:00 867. Multicatalytic, asymmetric Michael/Stetter
reaction of salicylaldehydes
and activated alkynes. T. Rovis,
C. M. Filloux, S. P. Lathrop
4:20 868. Synthesis of new chiral vicinal diamines
from isoquinoline and nitromethane.
M. Ahamed,M.H.Todd
4:40 869. Catalytic trifluoromethylation/ fluorination
of aromatic and heteroaromatic
compounds. F. Nowrouzi,R.A.Batey
5:00 870. Stereoretentive and mild halogenation
of cyclic alcohols catalyzed by titanium
(IV) reagents: Evidence for a new
front-side attack mechanism. S. Li,
D. Mondal, S. D. Lepore
Section D
Boston Convention & Exhibition Center
Room 203
Heterocycles and Aromatics
S. Sieburth, Organizer
C. Anderson, Presiding
1:00 871. Transition metal-catalyzed synthesis
of N-heterocycles from azides: Relationship
between mechanism and
metal. T. G. Driver,B.J.Stokes,
H. Dong, K. Sun, L. Urnezis
1:20 872. Synthesis of highly substituted
quinolines via a tandem ynamide benzannulation/iodocyclization
strategy.
T. P. WIllumstad, P. D. Boudreau,
R. L. Danheiser
1:40 873. �-Carboline library development
via inverse electron demand Diels-Alder
reaction of indoles with 1, 2, 4-triazines.
F. Ni,J.K.Johnson,S.E.Schaus,
J. K. Snyder
2:00 874. Synthetic routes to and reactivity
of bicyclic diazenium salts. J. Wyman,
M. Brewer
2:20 875. Studies toward concise synthesis
of calothrixin and its structural analogs.
O. B. Olubanwo, S. Rasapalli
2:40 876. Beckmann rearrangement and
ring annulation of porphyrin dione
oximes: Novel strategy toward the synthesis
of long wavelength chromophores.
J. Akhigbe,C.Brückner
3:00 877. Syntheses of 3-azido azetidinones
in [bmim][PF6]: A comparative study.
M. S. Chorghade, A. M. Rahatgaonkar,
A. M. Ghatole
3:20 878. Novel application of oxonium
(Meerwein) salts: Total synthesis of indole
alkaloids. V. Kumbam,M.Yu,
S. Rasapalli
3:40 879. Synthesis and properties of novel
benzisoxazole-N-oxides. M. G. Kociolek
4:00 880. Syntheses, structures, modification,
and optical properties of two isomericmeso-tetraaryl-2,3,12,13-tetrahydroxybacteriochlorins.
L. P. Samankumara, M. Zeller,
C. Brückner
4:20 881. Synthesis of novel porphyrinoids
through porphyrin N-oxidation.
S. Banerjee, M. Zeller, C. Brückner
4:40 882. 1,2,3-triazole coordinated boron
complex as efficient reagent for C-B
bond formation. T. Liao,X.Shi
5:00 883. Synthesis of tetrabenzoquadrannulene
(TBQ). B. Kumar,B.T.King
Section E
Boston Convention & Exhibition Center
Room 204A
Molecular Recognition and Self-Assembly
S. Sieburth, Organizer
S. Saha, Presiding
1:00 884. Coupling molecular recognition
with surface-enhanced resonance Raman
scattering for quantitative TNT sensing.
A. H. Flood, E. H. Witlicki, L. Jensen,
E. W. Wong, J. O. Jeppesen
1:20 885. Metal ion-assembled micro-collagen
heterotrimers. M. A. Case,
L. T. LeBruin, S. Banerjee
1:40 886. Engineering self-assembled platinate
nanostructures for cancer chemotherapy.
A. S. Paraskar,S.Soni,
S. Sengupta
2:00 887. Structural diversity in organic solid
derived from pyrazole-3,5-dicarboxylic
acid and amines. O. Ugono, A. M. Beatty
2:20 888. Highly selective fluorescent sensor
for pyrophosphate in aqueous solution
based on ESIPT turn-on. W. Chen,
Y. Pang
2:40 889. Alkynes of surprises: Acetylenes
are a versatile electron withdrawing
group for nucleophilic aromatic substitution.
J. W. Wackerly, J. L. Katz,
E. Braunstein, S. Carlin, M. Zhang,
N. Staley
3:00 890. Theoretical modeling of self-assembling
DNA base super-structures on
the Au(111) surface. R. E. Kelly,M.Mura,
L. N. Kantorovich
The official technical program
for the 240th National Meeting
is available at:
www.acs.org/boston2010
ORGN
TECH–95