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review of literature on clinical pancreatology - The Pancreapedia

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study was to evaluate the efficacy and safety <str<strong>on</strong>g>of</str<strong>on</strong>g> single-step EUS-guided endoscopicapproaches for treatment <str<strong>on</strong>g>of</str<strong>on</strong>g> sterile PFC. During a 3-year period, 77 c<strong>on</strong>secutive patients withsymptomatic, persistent sterile PFC were evaluated and treated with the linear EUS. It wasexcluded patients with grossly purulent collecti<strong>on</strong>s, chr<strong>on</strong>ic pseudocyst and those whosecytology diagnostic was neoplastic cyst <str<strong>on</strong>g>of</str<strong>on</strong>g> pancreas. 44 patients received a single 10-Frplastic straight stent under EUS or fluoroscopic c<strong>on</strong>trol (group I) and 33 <str<strong>on</strong>g>of</str<strong>on</strong>g> these underwent asingle-step complete aspirati<strong>on</strong> with a 19-gauge needle (group II). <strong>The</strong> mean size <str<strong>on</strong>g>of</str<strong>on</strong>g> thesterile PFC was 48 mm in group I and 28 mm in group II. Overall, endoscopic treatment wassuccessful in 70 (91 %) patients. <strong>The</strong> mean volume aspirated was 25 (18-65) ml. <strong>The</strong> totalnumber <str<strong>on</strong>g>of</str<strong>on</strong>g> procedures was 50 in group I and 41 punctures in group II. After a mean follow-up<str<strong>on</strong>g>of</str<strong>on</strong>g> 64 + 16 weeks there were 6 complicati<strong>on</strong>s (14 %): 2 recurrences (referred to surgery), 2developing abscesses (submitted a new EUS-guided endoscopic drainage with success), 1perforati<strong>on</strong> that died (2 %), and 1 case <str<strong>on</strong>g>of</str<strong>on</strong>g> bleeding (sent to surgery) in group I. In group IIthere were <strong>on</strong>ly 6 (18 %) recurrences (submitted a new EUS-guided aspirati<strong>on</strong>). N<strong>on</strong>e <str<strong>on</strong>g>of</str<strong>on</strong>g> thepatients undergoing single-step aspirati<strong>on</strong> developed infecti<strong>on</strong>s, perforati<strong>on</strong> or hemorrhage. Itwas c<strong>on</strong>cluded that recurrence <str<strong>on</strong>g>of</str<strong>on</strong>g> pancreatic pseudocysts after endoscopic treatment wassimilar, either by means <str<strong>on</strong>g>of</str<strong>on</strong>g> plastic stents or by complete single-step aspirati<strong>on</strong> [646].Other radiologyMost pancreatic pseudocysts are comm<strong>on</strong> complicati<strong>on</strong>s <str<strong>on</strong>g>of</str<strong>on</strong>g> acute or chr<strong>on</strong>ic pancreatitis.<strong>The</strong>y usually occur within the pancreas or in peripancreatic tissues, and are visualized asround or oval fluid collecti<strong>on</strong>s with thin or thick walls <strong>on</strong> computed tomography (CT) scans.However, pancreatic pseudocysts are <str<strong>on</strong>g>of</str<strong>on</strong>g>ten combined with various complicati<strong>on</strong>s, e.g.,various organ involvements, infecti<strong>on</strong>, hemorrhage with pseudoaneurysm formati<strong>on</strong>, rupturewith fistula formati<strong>on</strong>, or gastrointestinal or biliary obstructi<strong>on</strong>, which may necessitate promptinterventi<strong>on</strong> or surgery. A <str<strong>on</strong>g>review</str<strong>on</strong>g> illustrates the CT appearances <str<strong>on</strong>g>of</str<strong>on</strong>g> various complicati<strong>on</strong>sassociated with pancreatic pseudocysts [647].Case reportIt was reporter a huge pancreatic pseudocyst migrating to the psoas muscle and inguinalregi<strong>on</strong> [648].Intrahepatic pancreatic pseudocyst is an extremely rare complicati<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> acute pancreatitis.However, it was reported a case <str<strong>on</strong>g>of</str<strong>on</strong>g> a 37-year old diabetic male who presented with mildpancreatitis as predicted by modified Glasgow criteria. Abdominal CT scan showed a lefthepatic subcapsular cyst <str<strong>on</strong>g>of</str<strong>on</strong>g> 9x4 cm that progressively increased in size. CT guided aspirati<strong>on</strong><str<strong>on</strong>g>of</str<strong>on</strong>g> the cyst yielded 90 ml <str<strong>on</strong>g>of</str<strong>on</strong>g> yellow brown fluid with a high amylase c<strong>on</strong>centrati<strong>on</strong>. Bacterialculture <str<strong>on</strong>g>of</str<strong>on</strong>g> the fluid was negative. <strong>The</strong> patient dramatically improved after aspirati<strong>on</strong>; 3 m<strong>on</strong>thslater the patient was asymptomatic and follow-up abdominal ultrasound has shown completeresoluti<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> the cyst [649].It was reported a sp<strong>on</strong>taneous gastric drainage <str<strong>on</strong>g>of</str<strong>on</strong>g> a pancreatic pseudocyst [650].A patient with a pancreatic pseudocyst rupture into the portal vein with a resultantn<strong>on</strong>infectious systemic inflammatory resp<strong>on</strong>se syndrome and subsequent portal veinthrombosis diagnosed by computed tomography and ultras<strong>on</strong>ography was reported [651].Hemosuccus pancreaticusErosi<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> peripancreatic arteries in acute or chr<strong>on</strong>ic pancreatitis is a rare cause <str<strong>on</strong>g>of</str<strong>on</strong>g> bleedinginto gastrointestinal tract - hemosuccus pancreaticus. It was reported a case <str<strong>on</strong>g>of</str<strong>on</strong>g> a patient withchr<strong>on</strong>ic pancreatitis who developed acute bleeding into the gastrointestinal tract due to the

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