review of literature on clinical pancreatology - The Pancreapedia
review of literature on clinical pancreatology - The Pancreapedia
review of literature on clinical pancreatology - The Pancreapedia
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the stomach and duodenum. Analysis <str<strong>on</strong>g>of</str<strong>on</strong>g> the CT findings included evaluati<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> the locati<strong>on</strong>,c<strong>on</strong>tour, growth pattern, border, enhancement pattern, and enhancement grade <str<strong>on</strong>g>of</str<strong>on</strong>g> the tumor,as well as the presence <str<strong>on</strong>g>of</str<strong>on</strong>g> surface dimpling, prominent enhancement <str<strong>on</strong>g>of</str<strong>on</strong>g> overlying mucosa,and low intralesi<strong>on</strong>al attenuati<strong>on</strong>. <strong>The</strong> attenuati<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> each lesi<strong>on</strong>, the l<strong>on</strong>g diameter (LD), theshort diameter (SD), and the LD/SD ratio were measured. <strong>The</strong> typical locati<strong>on</strong> (prepyloricantrum and duodenum), endoluminal growth pattern, ill-defined border, prominentenhancement <str<strong>on</strong>g>of</str<strong>on</strong>g> overlying mucosa, and an LD/SD ratio <str<strong>on</strong>g>of</str<strong>on</strong>g> greater than 1.4 were found to besignificant for differentiating ectopic pancreas from other tumors. When at least two <str<strong>on</strong>g>of</str<strong>on</strong>g> thesefive criteria were used in combinati<strong>on</strong>, the sensitivity and specificity for diagnosing ectopicpancreas were 100 percent (14 <str<strong>on</strong>g>of</str<strong>on</strong>g> 14) and 83 percent (33 <str<strong>on</strong>g>of</str<strong>on</strong>g> 40), respectively. When four <str<strong>on</strong>g>of</str<strong>on</strong>g>these criteria were used, a sensitivity <str<strong>on</strong>g>of</str<strong>on</strong>g> 43 percent and a specificity <str<strong>on</strong>g>of</str<strong>on</strong>g> 100 percent wereachieved [114].Ectopic pancreatic tissue within a duodenal diverticulum has not been previously describedin the English-language <str<strong>on</strong>g>literature</str<strong>on</strong>g>. It was reported a case <str<strong>on</strong>g>of</str<strong>on</strong>g> a 52-year-old woman whopresented with a perforated duodenal diverticulum after upper endoscopy. Operativeresecti<strong>on</strong> and repair <str<strong>on</strong>g>of</str<strong>on</strong>g> the perforated diverticulum was performed, and, <strong>on</strong> microscopicexaminati<strong>on</strong>, ectopic pancreatic tissue was found within the diverticulum [115].Circumportal annulare<strong>The</strong>re have been 6 cases <str<strong>on</strong>g>of</str<strong>on</strong>g> circumportal pancreas reported, and 2 <str<strong>on</strong>g>of</str<strong>on</strong>g> them had the mainpancreatic duct in a retroportal dorsal porti<strong>on</strong>. This extremely uncomm<strong>on</strong> anomaly isasymptomatic and therefore incidentally discovered. For the surge<strong>on</strong>, it is important todiscover this during pancreatic resecti<strong>on</strong> so the pancreatic duct can be closed and fistula isavoided. It was now describe a third case where a circumportal pancreas had its mainpancreatic duct passing under the portal vein. <strong>The</strong> duct was identified and ligated. A fistuladid not occur [116].Pancreas annulareAnnular pancreas is a rare embry<strong>on</strong>al abnormality. Its manifestati<strong>on</strong> in adulthood is <str<strong>on</strong>g>of</str<strong>on</strong>g>tenpinpointed with a substantial delay, which is most <str<strong>on</strong>g>of</str<strong>on</strong>g>ten attributed to pancreatitis, biliarypathology or dyspepsia. It was presented a case <str<strong>on</strong>g>of</str<strong>on</strong>g> a 28-year-old woman who hadexacerbating symptoms <str<strong>on</strong>g>of</str<strong>on</strong>g> high bowel obstructi<strong>on</strong> from 20th week <str<strong>on</strong>g>of</str<strong>on</strong>g> pregnancy, progressingafter premature delivery. Diagnostic work-up revealed partial annular pancreas compressingthe duodenum. Despite attempts <str<strong>on</strong>g>of</str<strong>on</strong>g> c<strong>on</strong>servative treatment, her state deteriorated to such anextent that surgery was indicated and gastrojejunal bypass created. Her postoperativerecovery was uneventful. In cases in which symptoms <str<strong>on</strong>g>of</str<strong>on</strong>g> high bowel obstructi<strong>on</strong> in pregnancypersist and prostrati<strong>on</strong> occurs, we suggest close m<strong>on</strong>itoring and a more thorough diagnosticapproach. <strong>The</strong> questi<strong>on</strong> remains whether annular pancreas presents a cause <str<strong>on</strong>g>of</str<strong>on</strong>g> pathologicfindings, a c<str<strong>on</strong>g>of</str<strong>on</strong>g>actor, or a mere accidental diagnosis in the development <str<strong>on</strong>g>of</str<strong>on</strong>g> superposedpathologies [117].<strong>The</strong> purpose <str<strong>on</strong>g>of</str<strong>on</strong>g> <strong>on</strong>e study was to <str<strong>on</strong>g>review</str<strong>on</strong>g> the CT, MRI, and ERCP findings <str<strong>on</strong>g>of</str<strong>on</strong>g> annularpancreas in adults. A search <str<strong>on</strong>g>of</str<strong>on</strong>g> the radiology and ERCP databases at <strong>on</strong>e instituti<strong>on</strong> forcases <str<strong>on</strong>g>of</str<strong>on</strong>g> annular pancreas in adults yielded the records <str<strong>on</strong>g>of</str<strong>on</strong>g> 42 patients who underwent 29ERCP, 22 CT, and 13 MRI examinati<strong>on</strong>s. Nine <str<strong>on</strong>g>of</str<strong>on</strong>g> 24 (38 %) cases <str<strong>on</strong>g>of</str<strong>on</strong>g> annular pancreasdetected with CT or MRI did not have a radiologically complete ring <str<strong>on</strong>g>of</str<strong>on</strong>g> pancreatic tissuesurrounding the sec<strong>on</strong>d part <str<strong>on</strong>g>of</str<strong>on</strong>g> the duodenum. Three <str<strong>on</strong>g>of</str<strong>on</strong>g> the nine patients (33 %) withradiologically incomplete annular pancreas and six <str<strong>on</strong>g>of</str<strong>on</strong>g> the 15 patients (40 %) with completeannular pancreas had gastric outlet obstructi<strong>on</strong>. <strong>The</strong> presence <str<strong>on</strong>g>of</str<strong>on</strong>g> pancreatic tissueposterolateral to the sec<strong>on</strong>d part <str<strong>on</strong>g>of</str<strong>on</strong>g> the duodenum had a high sensitivity (92 %) andspecificity (100 %) for the presence <str<strong>on</strong>g>of</str<strong>on</strong>g> annular pancreas. <strong>The</strong> rates <str<strong>on</strong>g>of</str<strong>on</strong>g> pancreas divisum (37%) and chr<strong>on</strong>ic pancreatitis (48 %) were high in this cohort. It was c<strong>on</strong>cluded that annular