108. Pittenger GL, Taylor-Fishwick D, Vinik AI. <strong>The</strong> role <str<strong>on</strong>g>of</str<strong>on</strong>g> islet neogeneis-associated protein (INGAP)in pancreatic islet neogenesis. Curr Protein Pept Sci 2009; 10: 37-45.109. Hamelin R, Allagnat F, Haefliger JA, Meda P. C<strong>on</strong>nexins, diabetes and the metabolic syndrome.Curr Protein Pept Sci 2009; 10: 18-29.110. Li Z, Korzh V, G<strong>on</strong>g Z. DTA-mediated targeted ablati<strong>on</strong> revealed differential interdependence <str<strong>on</strong>g>of</str<strong>on</strong>g>endocrine cell lineages in early development <str<strong>on</strong>g>of</str<strong>on</strong>g> zebrafish pancreas. Differentiati<strong>on</strong> 2009 2009; 78:241-52.111. Dorrell C, Abraham SL, Lanx<strong>on</strong>-Cooks<strong>on</strong> KM, Canaday PS, Streeter PR, Grompe M. Isolati<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g>major pancreatic cell types and l<strong>on</strong>g-term culture-initiating cells using novel human surface. Stem CellRes 2008; 1: 183-94.112. Fraker CA, Ricordi C, Inverardi L, Domínguez-Bendala J. Oxygen: a master regulator <str<strong>on</strong>g>of</str<strong>on</strong>g>pancreatic development? Biol Cell 2009; 101: 431-40.113. Mulla C, Geras-Raaka E, Raaka BM, Gershengorn MC. High levels <str<strong>on</strong>g>of</str<strong>on</strong>g> thyrotropin-releasinghorm<strong>on</strong>e receptors activate programmed cell death in human pancreatic precursors. Pancreas 2009;38: 197-202.114. Kim JY, Lee JM, Kim KW, Park HS, Choi JY, Kim SH, Kim MA, Lee JY, Han JK, Choi BI. Ectopicpancreas: CT findings with emphasis <strong>on</strong> differentiati<strong>on</strong> from small gastrointestinal stromal tumor andleiomyoma. Radiology 2009; 252: 92-100.115. Volchok J, Massimi T, Wilkins S, Curletti E. Duodenal diverticulum: case report <str<strong>on</strong>g>of</str<strong>on</strong>g> a perforatedextraluminal diverticulum c<strong>on</strong>taining ectopic pancreatic tissue. Arch Surg 2009; 144: 188-90.116. Hashimoto Y, Ross AS, Traverso LW. Circumportal pancreas with retroportal main pancreaticduct. Pancreas 2009; 38: 713-5.117. Ledinsky M, Suić I, Babić N, Kujundzić S. Symptoms <str<strong>on</strong>g>of</str<strong>on</strong>g> annular pancreas exacerbated bypregnancy. Acta Clin Croat 2009; 48: 47-50.118. Sandrasegaran K, Patel A, Fogel EL, Zyromski NJ, Pitt HA. Annular pancreas in adults. Am JRoentgenol 2009; 193: 455-60.119. Arena F, Impellizzeri P, Scalfari G, Ant<strong>on</strong>uccio P, M<strong>on</strong>talto AS, Racchiusa S, Romeo C. Anuncomm<strong>on</strong> case <str<strong>on</strong>g>of</str<strong>on</strong>g> associate intrinsic and extrinsic stenosis <str<strong>on</strong>g>of</str<strong>on</strong>g> the duodenum in newborn. Pediatr MedChir 2008; 30: 212-4.120. Kim SW, Shin HC, Kim IY, Bae SB, Park JM. Duplicati<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> the spleen with a short pancreas. BrJ Radiol 2009; 82: e42-3.121. Paraskevas G, Papaziogas B, Ioannidis O, Kitsoulis P, Spanidou S. Double comm<strong>on</strong> bile duct: acase report. Acta Chir Belg 2009; 109: 507-9.122. Hac S, Nalecz A, Dobosz M, Reszetow J, Dobrowolski S, Friess H, Mihaljevic AL, Studniarek M,Jaskiewicz K, Sledzinski Z. Pancreatic duct diversity. Pancreas 2009; 38: 318-21.123. Sakpal SV, Sexcius L, Babel N, Chamberlain RS. Agenesis <str<strong>on</strong>g>of</str<strong>on</strong>g> the dorsal pancreas and itsassociati<strong>on</strong> with pancreatic tumors. Pancreas 2009; 38: 367-73.124. Lee JS, Kim SH, Jun DW, Han JH, Jang EC, Park JY, S<strong>on</strong> BK, Kim SH, Jo YJ, Park YS, Kim YS.Clinical implicati<strong>on</strong>s <str<strong>on</strong>g>of</str<strong>on</strong>g> fatty pancreas: correlati<strong>on</strong>s between fatty pancreas and metabolic syndrome.World J Gastroenterol 2009; 15: 1869-75.125. Balli O, Karcaaltincaba M, Karaosmanoglu D, Akata D. Multidetector computed tomographydiagnosis <str<strong>on</strong>g>of</str<strong>on</strong>g> fusi<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> pancreas and spleen c<strong>on</strong>firmed by magnetic res<strong>on</strong>ance imaging. J ComputAssist Tomogr 2009; 33: 291-2.
126. Toouli J. Sphincter <str<strong>on</strong>g>of</str<strong>on</strong>g> Oddi: functi<strong>on</strong>, dysfuncti<strong>on</strong>, and its management. J Gastroenteol Hepatol2009; 24 suppl 3: S57-62.127. Li CP, Qian W, Hou XH. Effect <str<strong>on</strong>g>of</str<strong>on</strong>g> four medicati<strong>on</strong>s associated with gastrointestinal motility <strong>on</strong>Oddi sphincter in the rabbit. Pancreatology 2009; 9: 615-20.128. Magni P, Dozio E, Ruscica M, Celotti F, Masini MA, Prato P, Broccoli M, Mambro A, Morè M,Strollo F. Feeding behavior in mammals including humans. Ann N Y Acad Sci 2009; 1163: 221-32.129. García M, Hernández-Lorenzo P, San Román JI, Calvo JJ. Pancreatic duct secreti<strong>on</strong>:experimental methods, i<strong>on</strong> transport mechanisms and regulati<strong>on</strong>. Physiol Biochem 2008; 64: 243-57.130. Rengman S, Weström B, Ahrén B, Pierzynowski SG. Arterial gastroduodenal infusi<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g>cholecystokinin-33 stimulates the exocrine pancreatic enzyme release via an enteropancreatic reflex,without affecting the endocrine insulin secreti<strong>on</strong> in pigs. Pancreas 2009; 38: 213-8.131. Gullo L, Sim<strong>on</strong>i P, Migliori M, Lucrezio L, Bassi M, Frau F, Lorenzo Costa P, Nesticò V. A study<str<strong>on</strong>g>of</str<strong>on</strong>g> pancreatic functi<strong>on</strong> am<strong>on</strong>g subjects over ninety years <str<strong>on</strong>g>of</str<strong>on</strong>g> age. Pancreatology 2009; 9: 240-4.132. Boros LG, Deng QG, Pandol SJ, Tsukamoto H, Go VLW, Lee WNP. Ethanol diversely alterspalmitate, stearate, and oleate metabolism in the liver and pancreas <str<strong>on</strong>g>of</str<strong>on</strong>g> rats using the deuterium oxidesingle tracer. Pancreas 2009; 38: e47-52.133. Mishra R, Sellin D, Radovan D, Gohlke A, Winter R. Inhibiting islet amyloid polypeptide fibrilformati<strong>on</strong> by the red wine compound resveratrol. Chembiochem 2009; 10: 445-9.134. Nauck MA. Unraveling the science <str<strong>on</strong>g>of</str<strong>on</strong>g> incretin biology. Am J Med 2009; 122 (6 suppl): S3-10.135. Mudaliar S, Henry RR. Incretin therapies: effects bey<strong>on</strong>d glycemic c<strong>on</strong>trol. Am J Med 2009; 122(6 suppl): S25-30.136. Campbell RK. Type 2 diabetes: where we are today: an overview <str<strong>on</strong>g>of</str<strong>on</strong>g> disease burden, currenttreatments, and treatment strategies. J Am Pharm Assoc 2009; 49 suppl 1: S3-9.137. Janosz KE, Zalesin KC, Miller WM, McCullough PA. Treating type 2 diabetes: incretin mimeticsand enhancers. <strong>The</strong>r Adv Cardiovasc Dis 2009; 3: 387-95.138. White J. Efficacy and safety <str<strong>on</strong>g>of</str<strong>on</strong>g> incretin based therapies: <strong>clinical</strong> trial data. J Am Pharm Assoc2009; 49 suppl 1: S30-40.139. Nauck MA. Unraveling the science <str<strong>on</strong>g>of</str<strong>on</strong>g> incretin biology. Eur J Intern Med 2009; 20 (suppl 2): S303-8.140. Mudaliar S, Henry RR. Incretin therapies: effects bey<strong>on</strong>d glycemic c<strong>on</strong>trol. Eur J Intern Med2009: 20 (suppl 2): S319-28.141. McCall MD, Toso C, Baetge EE, Shapiro AM. Are stem cells a cure for diabetes? Clin Sci 2009;118: 87-97.142. Foulis AK. Pancreatic pathology in type 1 diabetes in human. Novartis Found Symp 2008; 292: 2-13.143. Brandhorst H, Friberg A, Anderss<strong>on</strong> HH, Felldin M, Foss A, Salmela K, Lundgren T, Tibell A,Tufves<strong>on</strong> G, Korsgren O, Brandhorst D. <strong>The</strong> importance <str<strong>on</strong>g>of</str<strong>on</strong>g> tryptic-like activity in purified enzymeblends for efficient islet isolati<strong>on</strong>. Transplantati<strong>on</strong> 2009; 87: 370-5.144. Lau J, Carlss<strong>on</strong> PO. Low revascularizati<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> human islets when experimentally transplanted intothe liver. Transplantati<strong>on</strong> 2009; 87: 322-5.
- Page 1 and 2:
REVIEW OF LITERATURE ONCLINICAL PAN
- Page 3 and 4:
ABBREVIATIONAAPacute alcoholicABPac
- Page 5 and 6:
FMF AIPfocal mass-forming autoimmun
- Page 7 and 8:
ODPopen distal pancreatectomyOForga
- Page 9 and 10:
USUTDTVESDVTEZESWHOXIAPUnited State
- Page 11 and 12:
Ectopic pancreasCircumportal annula
- Page 13 and 14:
SymptomsEndocopic ultrasography (EU
- Page 15 and 16:
HSP27HuRIGF-1 receptorIntegrinesInt
- Page 17 and 18:
HemodialysisSerous cystadenomasSero
- Page 19 and 20:
CRPC-reactive proteinCRTchemoradiot
- Page 21 and 22:
ITNPintrathecal narcotics pumpJCGAI
- Page 23 and 24:
QSRquantitative systematic
- Page 25 and 26:
PANCREATIC HISTORYEarly conceptsPan
- Page 27 and 28:
derived from broadly Harveian anato
- Page 29 and 30:
acute appendicitis, intestinal obst
- Page 31 and 32:
dogma and its implied presence <str
- Page 33 and 34:
In the late 19th century, explorato
- Page 35 and 36:
performed. In 1880, Carl Thiersch <
- Page 37 and 38:
cancer was reported by Nestor Dimit
- Page 39 and 40:
Modern pancreatic historyHoward Reb
- Page 41 and 42:
PANCREATIC DEVELOPMENT, EMBRYOLOGY
- Page 43 and 44:
preparations. They were also employ
- Page 45 and 46:
pancreas can be diagnosed without t
- Page 47 and 48:
PANCREATIC PHYSIOLOGYSphincter <str
- Page 49 and 50:
acid profile and d
- Page 51 and 52:
hormones. The roles of</str
- Page 53 and 54:
ACUTE PANCREATITISAcute pancreatiti
- Page 55 and 56:
necrosis or a severe course, and lo
- Page 57 and 58:
of 245 cases <stro
- Page 59 and 60:
plasty of the mino
- Page 61 and 62:
no significant difference. The stro
- Page 63 and 64:
Urinary trypsinogen-2There is not a
- Page 65 and 66:
groups. None of th
- Page 67 and 68:
evaluated the presence or absence <
- Page 69 and 70:
adical, etc, further studies are st
- Page 71 and 72:
Precut at sphincterotomyPrecut is p
- Page 73 and 74:
indications [204].Hypercalcemia-ind
- Page 75 and 76:
endoscopic retrograde cholangiopanc
- Page 77 and 78:
(before ERCP), serum TAP was detect
- Page 79 and 80:
concentration and clinical symptoms
- Page 81 and 82:
However, the recipients of<
- Page 83 and 84:
less safe for predominantly cephali
- Page 85 and 86:
increased mortality. Mortality in p
- Page 87 and 88:
Epidemiology and demographyChinaCHR
- Page 89 and 90:
for the first time the significance
- Page 91 and 92:
endoscopic ultrasound accurately de
- Page 93 and 94:
possible to at least reduce relapse
- Page 95 and 96:
etiologies have been proposed and a
- Page 97 and 98:
patients, can be performed with mod
- Page 99 and 100:
negative binomial model. One hundre
- Page 101 and 102:
Halofuginone did n
- Page 103 and 104:
years, the risk of
- Page 105 and 106:
patients with a proven exocrine pan
- Page 107 and 108:
high-risk patients [296].Cystic fib
- Page 109 and 110:
TNF-alpha promoter were performed.
- Page 111 and 112:
were validated in another series <s
- Page 113 and 114:
vascular invasion (14/15). Abnormal
- Page 115 and 116:
and other lymph nodes, salivary gla
- Page 117 and 118:
HEREDITARY PANCREATITISPatients wit
- Page 119 and 120:
Classification of
- Page 121 and 122:
historically, but recent life-style
- Page 123 and 124:
carcinogen exposure with cancer ris
- Page 125 and 126:
the risk of pancre
- Page 127 and 128:
conducted a cohort analysis <strong
- Page 129 and 130:
emain to be solved in screening for
- Page 131 and 132:
considered for women with Lynch syn
- Page 133 and 134:
Annexin A5Protein misfolding is a c
- Page 135 and 136:
CTNNB1To use fluorescence in situ h
- Page 137 and 138:
expression was not associated with
- Page 139 and 140:
(ECM) are not fully understood. In
- Page 141 and 142:
lines. However, the role of
- Page 143 and 144:
andomized to high-dose vitamin A, t
- Page 145 and 146:
Synuclein-gammaPerineural invasion
- Page 147 and 148:
interventions. Cancer nests were ma
- Page 149 and 150:
the optimal combination of<
- Page 151 and 152:
which is essential in tumor and nod
- Page 153 and 154:
provide conclusive evidence for the
- Page 155 and 156:
MD-CT is suitable for evaluating tu
- Page 157 and 158:
approved study and imaged during sh
- Page 159 and 160:
Quantum dotsIt was reported the suc
- Page 161 and 162:
clearly have a very high incidence
- Page 163 and 164:
patients for operation and when cou
- Page 165 and 166:
demonstrated using the confocal mic
- Page 167 and 168:
cancer [468].To evaluate pancreatic
- Page 169 and 170:
pancreaticoduodenectomy (PD). The s
- Page 171 and 172:
safe option as an interposition gra
- Page 173 and 174:
a curative surgery, while double-by
- Page 175 and 176:
%), pseudocyst (3 %), and trauma (3
- Page 177 and 178:
procedure is failing to progress la
- Page 179 and 180:
Glucos metabolism after pancreatect
- Page 181 and 182:
Quality of lifeOne
- Page 183 and 184:
was observed in the NACRT group. Th
- Page 185 and 186:
interval 0.80 to 0.96]. On subgroup
- Page 187 and 188:
ate in patients with pancreatic can
- Page 189 and 190: median survival time was 7 versus 7
- Page 191 and 192: and the endoscopic ultrasound-guide
- Page 193 and 194: local recurrence of</strong
- Page 195 and 196: CurcuminCurcumin has been shown to
- Page 197 and 198: size >1.5 cm (odds ratio 2.4), and
- Page 199 and 200: adenocarcinoma must be addressed at
- Page 201 and 202: Molecular biologyCD44v6The purpose
- Page 203 and 204: IPMN were studied. Two-dimensional
- Page 205 and 206: the NT-IPMN-Br group. Eleven patien
- Page 207 and 208: metastatic neoplasms showing cystic
- Page 209 and 210: Solid pseudopapillary neoplasms <st
- Page 211 and 212: The tumor cells were negative for p
- Page 213 and 214: Duodenal tumorsColorectal polyposis
- Page 215 and 216: Colorectal carcinomaPancreatic meta
- Page 217 and 218: It was described a case of<
- Page 219 and 220: evaluation. The purpose of<
- Page 221 and 222: perforation of a p
- Page 223 and 224: the 28 had pancreatic duct injury <
- Page 225 and 226: ENDOCRINE PANCREATIC TUMORSHistoryA
- Page 227 and 228: 25-111 pg/mL). Mean Hemoglobin A1C
- Page 229 and 230: clinical features, misdiagnosis occ
- Page 231 and 232: achieved in selected cases by tissu
- Page 233 and 234: Overall survivalPancreatic neuroend
- Page 235 and 236: REFERENCES001. Metter CC. History <
- Page 237 and 238: 044. Fitz RH. The symptomatology an
- Page 239: 089. McClusky DA, Skandalakis LJ, C
- Page 243 and 244: 162. Deshpande AV, Thomas G, Shun A
- Page 245 and 246: 196. Park JH, Lee TH, Cheon SL, Sun
- Page 247 and 248: 226. Botoi G, Andercou A. Early and
- Page 249 and 250: 260. Nakamura H, Morifuji M, Muraka
- Page 251 and 252: 292. Borak GD, Romagnuolo J, Alsola
- Page 253 and 254: 324. Oh HC, Kim MH, Choi KS, Moon S
- Page 255 and 256: 358. Koornstra JJ, Mourits MJ, Sijm
- Page 257 and 258: 391. Chen JY, Amos CI, Merriman KW,
- Page 259 and 260: 421. Horwhat JD, Gerke H, Acosta RD
- Page 261 and 262: 451. Zamboni G, Capelli P, Scarpa A
- Page 263 and 264: 483. Rosa F, Pacelli F, Papa V, Tor
- Page 265 and 266: 517. Isayama H, Nakai Y, Togawa O,
- Page 267 and 268: 545. Pino MS, Milella M, Gelibter A
- Page 269 and 270: 576. Tanno S, Sasajima J, Koizumi K
- Page 271 and 272: 605. Ayadi L, Ellouze S, Khabir A,
- Page 273 and 274: 637. Nagar AM, Raut AA, Morani AC,
- Page 275 and 276: 670. Lejonklou M, Edfeldt K, Johans