Hepatogastroenterology 2009; 56: 515-8.591. Yo<strong>on</strong> LS, Catalano OA, Fritz S, Ferr<strong>on</strong>e CR, Hahn PF, Sahani DV. Another dimensi<strong>on</strong> inmagnetic res<strong>on</strong>ance cholangiopancreatography: comparis<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> 2- and 3-dimensi<strong>on</strong>al magneticres<strong>on</strong>ance cholangiopancreatography for the evaluati<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> intraductal papillary mucinous neoplasm <str<strong>on</strong>g>of</str<strong>on</strong>g>the pancreas. J Comput Assist Tomogr 2009; 33: 363-8.592. Ringold DA, Shr<str<strong>on</strong>g>of</str<strong>on</strong>g>f P, Sikka SK, Ylagan L, J<strong>on</strong>nalagadda S, Early DS, Edmundowicz SA, Azar R.Pancreatitis is frequent am<strong>on</strong>g patients with side-branch intraductal papillary mucinous neoplasiadiagnosed by EUS. Gastrointest Endosc 2009 Jun 23 [Epub ahead <str<strong>on</strong>g>of</str<strong>on</strong>g> print].593. Pala C, Serventi F, Scognamillo F, Attene F, Pisano IP, Cugia L, Mel<strong>on</strong>i M, Trignano M. Cysticpancreatic tumor treated by distal spleno-pancreatectomy with occasi<strong>on</strong>al diagnosis <str<strong>on</strong>g>of</str<strong>on</strong>g> neuroendocrinetumor: case report. Ann Ital Chir 2008; 79: 451-6 (in Italian).594. Oh SJ, Lee SJ, Lee HY, Paik YH, Lee DK, Lee KS, Chung JB, Yu JS, Yo<strong>on</strong> DS. Extrapancreatictumors in intraductal papillary mucinous neoplasm <str<strong>on</strong>g>of</str<strong>on</strong>g> the pancreas. Korean J Gastroenterol 2009; 54:162-6 (in Korean).595. Hir<strong>on</strong>o S, Tani M, Kawai M, Ina S, Nishioka R, Miyazawa M, Fujita Y, Uchiyama K, Yamaue H.Treatment strategy for intraductal papillary mucinous neoplasm <str<strong>on</strong>g>of</str<strong>on</strong>g> the pancreas based <strong>on</strong> malignantpredictive factors. Arch Surg 2009; 144: 345-9.596. Gill KR, Pelaez-Luna M, Keaveny A, Woodward TA, Wallace MB, Chari ST, Smyrk TC,Takahashi N, Clain JE, Levy MJ, Pears<strong>on</strong> RK, Petersen BT, Topazian MD, Vege SS, Kendrick M,Farnell MB, Raim<strong>on</strong>do M. Branch duct intraductal papillary mucinous neoplasm <str<strong>on</strong>g>of</str<strong>on</strong>g> the pancreas insolid organ transplant recipients. Am J Gastroenterol 2009; 104: 1256-61.597. Nara S, Shimada K, Sakamoto Y, Esaki M, Kosuge T, Hiraoka N. Clinical significance <str<strong>on</strong>g>of</str<strong>on</strong>g> frozensecti<strong>on</strong> analysis during resecti<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> intraductal papillary mucinous neoplasm: should a positivepancreatic margin for adenoma or borderline lesi<strong>on</strong> be resected additi<strong>on</strong>ally? J Am Coll Surg 2009;209: 614-21.598. Ishikawa T, Takeda K, Itoh M, Imaizumi T, Oguri K, Takahashi H, Kasuga H, Toriyama T, MatsuoS, Hirooka Y, Itoh A, Kawashima H, Kasugai T, Ohno E, Miyahara R, Ishigami M, Katano Y, OhmiyaN, Niwa Y, Goto H. Prevalence <str<strong>on</strong>g>of</str<strong>on</strong>g> pancreatic cystic lesi<strong>on</strong>s including intraductal papillary mucinousneoplasms in patients with end-stage renal disease <strong>on</strong> hemodialysis. Pancreas 2009; 38: 175-9.599. Wargo JA, Fernandez-del-Castillo C, Warshaw AL. Management <str<strong>on</strong>g>of</str<strong>on</strong>g> pancreatic serouscystadenomas. Adv Surg 2009; 43: 23-34.600. Allen PJ, Qin LX, Tang L, Klimstra D, Brennan MF, Lokshin A. Pancreatic cyst fluid proteinexpressi<strong>on</strong> pr<str<strong>on</strong>g>of</str<strong>on</strong>g>iling for discriminating between serous cystadenoma and intraductal papillarymucinous neoplasm. Ann Surg 2009; 250: 754-60.601. Agarwal N, Kumar S, Dass J, Arora VK, Rathi V. Diffuse pancreatic serous cystadenomaassociated with neuroendocrine carcinoma: a case report and <str<strong>on</strong>g>review</str<strong>on</strong>g> <str<strong>on</strong>g>of</str<strong>on</strong>g> <str<strong>on</strong>g>literature</str<strong>on</strong>g>. JOP 2009; 10: 55-8.602. Marsh WL, Col<strong>on</strong>na J, Yearsley M, Bloomst<strong>on</strong> M, Frankel WL. Calp<strong>on</strong>in is expressed in serouscystadenomas <str<strong>on</strong>g>of</str<strong>on</strong>g> the pancreas but not in adenocarcinomas or endocrine tumors. ApplImmunohistochem Mol Morphol 2009; 17: 216-9.603. Akiyama T, Sadahira Y, Irei I, Nishimura H, Hida AI, Notohara K, Hamazaki S. Pancreatic serousmicrocystic adenoma with extensive <strong>on</strong>cocytic change. Pathol Int 2009; 59: 102-6.604. Hisa T, Ohkubo H, Shiozawa S, Ishigame H, Ueda M, Takamatsu M, Furutake M. Mucinouscystadenoma <str<strong>on</strong>g>of</str<strong>on</strong>g> the pancreas with huge mural hematoma. Pathol Int 2009; 59: 762-5.
605. Ayadi L, Ellouze S, Khabir A, Daoud E, Bahri I, Trigui D, Mnif Z, Beyrouti MI, Makni S,Boudawara T. Frantz's tumor: anatomo<strong>clinical</strong> study <str<strong>on</strong>g>of</str<strong>on</strong>g> six Tunisian cases. Rev Med Brux 2008; 29:572-6 (in French).606. Reddy S, Camer<strong>on</strong> JL, Scudiere J, Hruban RH, Fishman EK, Ahuja N, Pawlik TM, Edil BH,Schulick RD, Wolfgang CL. Surgical management <str<strong>on</strong>g>of</str<strong>on</strong>g> solid-pseudopapillary neoplasms <str<strong>on</strong>g>of</str<strong>on</strong>g> the pancreas(Franz or Hamoudi tumors): a large single-instituti<strong>on</strong>al series. J Am Coll Surg 2009; 208: 950-7.607. Kang CM, Kim HK, Kim H, Choi GH, Kim KS, Choi JS, Lee WJ. Expressi<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> Wnt target genesin solid pseudopapillary tumor <str<strong>on</strong>g>of</str<strong>on</strong>g> the pancreas: a pilot study. Pancreas 2009; 38: e53-9.608. Matos JM, Grützmann R, Agaram NP, Saeger HD, Kumar HR, Lillemoe KD, Schmidt CM. Solidpseudopapillary neoplasms <str<strong>on</strong>g>of</str<strong>on</strong>g> the pancreas: a multi-instituti<strong>on</strong>al study <str<strong>on</strong>g>of</str<strong>on</strong>g> 21 patients. J Surg Res 2009;157: e137-42.609. Reddy S, Wolfgang CL. Solid pseudopapillary neoplasms <str<strong>on</strong>g>of</str<strong>on</strong>g> the pancreas. Adv Surg 2009; 43:269-82.610. Kim SH, Cho YT, Kw<strong>on</strong> HJ, An CM, Kim IH, Kim SW, Lee ST, Lee SO. A case <str<strong>on</strong>g>of</str<strong>on</strong>g> atypical solidpseudopapillarytumor <str<strong>on</strong>g>of</str<strong>on</strong>g> the pancreas. Korean J Gastroenterol 2009; 54: 252-6 (in Korean).611. Farah-Klibi F, El Amine O, Rammeh S, Ben Rejeb M, Ferchiou M, Kourda J, Abdessalem M,Zaouche A, Ben Jilani S, Zermani R. Solid pseudopapillary tumors <str<strong>on</strong>g>of</str<strong>on</strong>g> the pancreas: a pediatric casereport. Tunis Med 2008; 86: 928-31 (in French).612. Chung YE, Kim MJ, Choi JY, Lim JS, H<strong>on</strong>g HS, Kim YC, Cho HJ, Kim KA, Choi SY.Differentiati<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> benign and malignant solid pseudopapillary neoplasms <str<strong>on</strong>g>of</str<strong>on</strong>g> the pancreas. J ComputAssist Tomogr 2009; 33: 689-94.613. Burford H, Baloch Z, Liu X, Jhala D, Siegal GP, Jhala N. E-cadherin/beta-catenin and CD10: alimited immunohistochemical panel to distinguish pancreatic endocrine neoplasm from solidpseudopapillary neoplasm <str<strong>on</strong>g>of</str<strong>on</strong>g> the pancreas <strong>on</strong> endoscopic ultrasound-guided fine-needle aspirates <str<strong>on</strong>g>of</str<strong>on</strong>g>the pancreas. Am J Clin Pathol 2009; 132: 831-9.614. Kanter J, Wils<strong>on</strong> DB, Strasberg S. Downsizing to resectability <str<strong>on</strong>g>of</str<strong>on</strong>g> a large solid and cystic papillarytumor <str<strong>on</strong>g>of</str<strong>on</strong>g> the pancreas by single-agent chemotherapy. J Pediatr Surg 2009; 44: e23-5.615. Terada T. Intraductal tubular carcinoma, intestinal type, <str<strong>on</strong>g>of</str<strong>on</strong>g> the pancreas. Pathol Int 2009; 59: 53-8.616. Vo<strong>on</strong>g KR, Davis<strong>on</strong> J, Pawlik TM, Uy MO, Hsu CC, Winter J, Hruban RH, Laheru D, Rudra S,Swartz MJ, Nathan H, Edil BH, Schulick R, Camer<strong>on</strong> JL, Wolfgang CL, Herman JM. Resectedpancreatic adenosquamous carcinoma: clinicopathologic <str<strong>on</strong>g>review</str<strong>on</strong>g> and evaluati<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> adjuvantchemotherapy and radiati<strong>on</strong> in 38 patients. Hum Pathol 2010; 41: 113-22.617. van Wensen RJ, Bosscha K, Jager GJ, van der Linden JC, Fijnheer R. An invasive process in thepancreas: sometimes lymphoma. Ned Tijdschr Geneeskd 2009; 153: B164 (in Dutch).618. Luo G, Jin C, Fu D, L<strong>on</strong>g J, Yang F, Ni Q. Primary pancreatic lymphoma. Tumori 2009; 95: 156-9.619. Yamagami Y, Ueshima S, Mizutani S, Uchikoshi F, Ohyama T, Yoshidome K, Tori M, Hiraoka K,Takahashi H, Sueyoshi K, Taira M, Kido T, Sakamaki Y, Yasukawa M, Oka K, Tsujimoto M, NakaharaM, Nakao K. An autopsied case <str<strong>on</strong>g>of</str<strong>on</strong>g> giant small cell carcinoma <str<strong>on</strong>g>of</str<strong>on</strong>g> the pancreas. Gan To Kagaku Ryoho2009; 36: 123-5 (in Japanese).620. Hurtuk MG, Hughes C, Shoup M, Aranha GV. Does lymph node ratio impact survival in resectedperiampullary malignancies? Am J Surg 2009; 197: 348-52.
- Page 1 and 2:
REVIEW OF LITERATURE ONCLINICAL PAN
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ABBREVIATIONAAPacute alcoholicABPac
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FMF AIPfocal mass-forming autoimmun
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ODPopen distal pancreatectomyOForga
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USUTDTVESDVTEZESWHOXIAPUnited State
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Ectopic pancreasCircumportal annula
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SymptomsEndocopic ultrasography (EU
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HSP27HuRIGF-1 receptorIntegrinesInt
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HemodialysisSerous cystadenomasSero
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CRPC-reactive proteinCRTchemoradiot
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ITNPintrathecal narcotics pumpJCGAI
- Page 23 and 24:
QSRquantitative systematic
- Page 25 and 26:
PANCREATIC HISTORYEarly conceptsPan
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derived from broadly Harveian anato
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acute appendicitis, intestinal obst
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dogma and its implied presence <str
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In the late 19th century, explorato
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performed. In 1880, Carl Thiersch <
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cancer was reported by Nestor Dimit
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Modern pancreatic historyHoward Reb
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PANCREATIC DEVELOPMENT, EMBRYOLOGY
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preparations. They were also employ
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pancreas can be diagnosed without t
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PANCREATIC PHYSIOLOGYSphincter <str
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acid profile and d
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hormones. The roles of</str
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ACUTE PANCREATITISAcute pancreatiti
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necrosis or a severe course, and lo
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of 245 cases <stro
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plasty of the mino
- Page 61 and 62:
no significant difference. The stro
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Urinary trypsinogen-2There is not a
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groups. None of th
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evaluated the presence or absence <
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adical, etc, further studies are st
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Precut at sphincterotomyPrecut is p
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indications [204].Hypercalcemia-ind
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endoscopic retrograde cholangiopanc
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(before ERCP), serum TAP was detect
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concentration and clinical symptoms
- Page 81 and 82:
However, the recipients of<
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less safe for predominantly cephali
- Page 85 and 86:
increased mortality. Mortality in p
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Epidemiology and demographyChinaCHR
- Page 89 and 90:
for the first time the significance
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endoscopic ultrasound accurately de
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possible to at least reduce relapse
- Page 95 and 96:
etiologies have been proposed and a
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patients, can be performed with mod
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negative binomial model. One hundre
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Halofuginone did n
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years, the risk of
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patients with a proven exocrine pan
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high-risk patients [296].Cystic fib
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TNF-alpha promoter were performed.
- Page 111 and 112:
were validated in another series <s
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vascular invasion (14/15). Abnormal
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and other lymph nodes, salivary gla
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HEREDITARY PANCREATITISPatients wit
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Classification of
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historically, but recent life-style
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carcinogen exposure with cancer ris
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the risk of pancre
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conducted a cohort analysis <strong
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emain to be solved in screening for
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considered for women with Lynch syn
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Annexin A5Protein misfolding is a c
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CTNNB1To use fluorescence in situ h
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expression was not associated with
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(ECM) are not fully understood. In
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lines. However, the role of
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andomized to high-dose vitamin A, t
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Synuclein-gammaPerineural invasion
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interventions. Cancer nests were ma
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the optimal combination of<
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which is essential in tumor and nod
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provide conclusive evidence for the
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MD-CT is suitable for evaluating tu
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approved study and imaged during sh
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Quantum dotsIt was reported the suc
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clearly have a very high incidence
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patients for operation and when cou
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demonstrated using the confocal mic
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cancer [468].To evaluate pancreatic
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pancreaticoduodenectomy (PD). The s
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safe option as an interposition gra
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a curative surgery, while double-by
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%), pseudocyst (3 %), and trauma (3
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procedure is failing to progress la
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Glucos metabolism after pancreatect
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Quality of lifeOne
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was observed in the NACRT group. Th
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interval 0.80 to 0.96]. On subgroup
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ate in patients with pancreatic can
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median survival time was 7 versus 7
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and the endoscopic ultrasound-guide
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local recurrence of</strong
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CurcuminCurcumin has been shown to
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size >1.5 cm (odds ratio 2.4), and
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adenocarcinoma must be addressed at
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Molecular biologyCD44v6The purpose
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IPMN were studied. Two-dimensional
- Page 205 and 206:
the NT-IPMN-Br group. Eleven patien
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metastatic neoplasms showing cystic
- Page 209 and 210:
Solid pseudopapillary neoplasms <st
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The tumor cells were negative for p
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Duodenal tumorsColorectal polyposis
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Colorectal carcinomaPancreatic meta
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It was described a case of<
- Page 219 and 220: evaluation. The purpose of<
- Page 221 and 222: perforation of a p
- Page 223 and 224: the 28 had pancreatic duct injury <
- Page 225 and 226: ENDOCRINE PANCREATIC TUMORSHistoryA
- Page 227 and 228: 25-111 pg/mL). Mean Hemoglobin A1C
- Page 229 and 230: clinical features, misdiagnosis occ
- Page 231 and 232: achieved in selected cases by tissu
- Page 233 and 234: Overall survivalPancreatic neuroend
- Page 235 and 236: REFERENCES001. Metter CC. History <
- Page 237 and 238: 044. Fitz RH. The symptomatology an
- Page 239 and 240: 089. McClusky DA, Skandalakis LJ, C
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- Page 255 and 256: 358. Koornstra JJ, Mourits MJ, Sijm
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