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Name (Title):
Mingsheng Xu (ICYS Researcher, NIMS)
Affiliation:
International Center for Young Scientist, Sengen, NIMS
Address:
1-2-1 Sengen, Tsukuba, Ibaraki 305-0047, Japan
Email: XU.Mingsheng@nims.go.jp
Home Page: http://www.nims.go.jp/icysimat/researchers.html
Presentation Title:
ZnO nanostructures-mediated cell viability
Abstract:
The chemical design and synthesis of nanomaterials have
fueled the growth of nanotechnology. The unusual
physicochemical properties of nanomaterials are attributable
to their small size (surface area and size distribution),
chemical composition (purity, crystallinity, electronic
properties, etc.), surface structure (surface reactivity, surface
groups, inorganic or organic coatings, etc.), solubility, shape,
and aggregation. Distinct optical, electronic, or magnetic
properties can be tuned during chemical synthesis. Currently,
more than 350 nanoproducts are already on the market, used
in sporting goods, tires, stain-resistant clothing, sunscreens,
cosmetics, and electronics and will also be increasingly
utilized in medicine for purposes of diagnosis, imaging, and
drug delivery. The increased presence of nanomaterials in
commercial products raises concerns about adverse effects on
the toxicological and environmental effects of direct and
indirect exposure to these materials.
In this presentation, we evaluate the cell viability of
different sized and shaped ZnO nanomaterials because of the
importance and availability of a rich genre of ZnO
nanostructures. The finding of this study will have
implication in the chemical design and synthesis of safe
nanomaterials for variously applications.
Co-authors:
Daisuke Fujita, Shoko Kajiwara, Xianglan Li, Takashi Minowa and Nobutaka Hanagata
References:
[1] A.D. Maynard, Nature 444, 267 (2006).
[2] A. Nel, et al., Science 311, 622 (2006).
[3] N. Lewinski, et al., Small 4, 26 (2008).
[4] C. A. Poland, et al., Nature Nanotechnol. 3, 423 (2008).
[5] A. Takagi, et al., J. Toxicol. Sci. 33, 105 (2008).
[6] Z. L. Wang, Materials Today 7, 26 (2004).
122
Poster Session PIR-9
Figure 1 NIH3T3 cell viability after
incubated with ZnO nanoparticles
(~60 nm) with dose of (a) 0 and (b)
12.5 µg/ml for 48 h.