Duke University 2009-2010 - Office of the Registrar - Duke University

tissue types to be reviewed include cartilage, skin equivalents, blood vessels, myocardium and heart valves, and
bioartificial livers. Prerequisites: Mathmetics 108 or consent of instructor. Instructor: Bursac. 3 units.
252. Neural Signal Acquisition (GE, IM, EL). This course will be an exploration of analog and digital signal processing
techniques for measuring and characterizing neural signals. the analog portion will cover electrodes, amplifiers, filters
and A/D converters for recording neural electrograms and EEGs. The digital portion will cover methods of EEG
processing including spike detection and spike sorting. A course pack of relevant literature will be used in lieu of a
textbook. Students will be required to write signal-processing algorithms. Prerequisite: Biomedical Engineering 154L.
Instructor: Wolf. 3 units.
253. Computational Neuroengineering (GE, EL). This course introduces students to the fundamentals of computational
modeling of neurons and neuronal circuits and the decoding of information from populations of spike trains. Topics
include: integrate and fire neurons, Spike Response Models, Homogeneous and Inhomogeneous Poisson processes,
neural circuits, Weiner (optimal), Adaptive Filters, neural networks for classification, population vector coding and
decoding. Programming assignments and projects will be carried out using MATLAB. Prerequisites: BME 101/201 or
equivalent. Instructor: Henriquez. 3 units.
254. Fundamentals of Electrical Stimulation of the Nervous System (GE, EL). This course presents a quantitative
approach to the fundamental principles, mechanisms, and techniques of electrical stimulation required for nondamaging
and effective application of electrical stimulation. Consent of instructor required. Instructor: Grill. 3 units.
258L. Genome Science & Technology Lab (GE, MC). Hands-on experience on using and developing advanced
technology platforms for genomics and proteomics research. Experiments may include nucleic acid amplification and
quantification, lab-on-chip, bimolecular separation and detection, DNA sequencing, SNP genotyping, microarrays, and
synthetic biology techniques. Laboratory exercises and designing projects are combined with lectures and literature
reviews. Prior knowledge in molecular biology and biochemistry is required. Instructor consent required. Instructor:
Tian. Variable credit. C-L: Computational Biology and Bioinformatics 222
260L. Devices for People with Disabilities (DR or GE, IM, BB). Design of custom devices to aid disabled individuals.
Students will be paired with health care professionals at local hospitals who will supervise the development of projects
for specific clients. Formal engineering design principles will be emphasized; overview of assistive technologies, patent
issues, engineering ethics. Oral and written reports will be required. Selected projects may be continued as independent
study. Prerequisite: Biomedical Engineering 154L and Statistics 113. Consent of instructor required. Instructor: Bohs
or Goldberg. 3 units.
261L. Electronic Designs for the Developing World (DR or GE, IM). Design of custom devices to help the specific and
unique needs of developing world hospitals. Formal engineering design principles will be emphasized; overview of
developing world conditions, patent issues, engineering ethics. Designs must be based on microcontroller or equivalent
electronic circuitry. Oral and written reports will be required. Students may elect to personally deliver their projects to
a developing world hospital, if selected, in the summer following the course. Prerequisites: Biomedical Engineering
154L and Statistics 113. Consent of instructor required. Instructor: Malkin. 3 units.
262L. Design for the Developing World (DR or GR). Design of custom devices to help the specific and unique needs
of developing world hospitals. Formal engineering design principles will be emphasized; overview of developing world
conditions, patent issues, engineering ethics. Oral and written reports will be required. Students may elect to personally
deliver their projects to a developing world hospital, if selected, in the summer following the course. Prerequisite:
Biomedical Engineering 154L and Statistics 113. Consent of instructor required. Instructor: Malkin. 3 units.
264L. Medical Instrument Design (DR or GE, IM). General principles of signal acquisition, amplification processing,
recording, and display in medical instruments. System design, construction, and evaluation techniques will be
emphasized. Methods of real-time signal processing will be reviewed and implemented in the laboratory. Each student
will design, construct, and demonstrate a functional medical instrument and collect and analyze data with that
instrument. Formal write-ups and presentations of each project will be required. Prerequisite: Biomedical Engineering
154L and Statistics 113, or equivalent or senior standing. Instructor: Malkin, S. Smith, Trahey, or Wolf. 4 units.
265. Advanced Topics in Biomedical Engineering. Advanced subjects related to programs within biomedical
engineering tailored to fit the requirements of a small group. Consent of instructor required. Instructor: Staff. 3 units.
265L. Advanced Topics with Lab. To be used as a "generic" course number for any advanced topics course with lab
sections. Instructor: Staff. 3 units.
301. Biological Engineering Seminar Series (CBIMMS and CBTE). 1 unit. C-L: see Mechanical Engineering and
Materials Science 301
302. Biological Engineering Seminar Series (CBIMMS and CBTE). 1 unit. C-L: see Mechanical Engineering and
Materials Science 302
311. BME Graduate Seminars. Two semester, weekly seminars series required of all BME graduate students. Students
are exposed to the breadth of research topics in BME via seminars given by BME faculty, advanced graduate students,
and invited speakers. At the end of each semester students are required to write a synopsis of the seminars attended. More
than three unexcused absences will result in a failing grade. Instructor: Staff. 0 units.
Departments, Programs, and Course Offerings 105