Duke University 2009-2010 - Office of the Registrar - Duke University

J. York; Assistant Professors Hockman (Surgery), Macalpine, Muoio (Medicine), Rathmell, S. York; Medical Research
Professor Wilson
Pharmacology is the science of drug action on biological systems. It encompasses the study of targets of drug action,
the mechanisms by which drugs act, the therapeutic and toxic effects of drugs, as well as the development of new
therapeutic agents. As the study of pharmacology is interdisciplinary, the graduate program in pharmacology is diverse
and flexible. The focus of the graduate program in pharmacology is to prepare qualified individuals for a career in
independent research. The Department currently has 23 primary faculty and 22 secondary faculty with primary
appointments in departments such as molecular genetic and microbiology, cell biology, cardiology, medicine, and
neurobiology. The collaborative and collegial atmosphere between faculty and students provides a wide diversity of
research opportunities.
Pharmacology and Cancer Biology (PHARM)
210. Research Independent Study in Science Education. Individual research in a field of science education (with
reference to pharmacology) at the precollege/college level, under the supervision of a faculty member, resulting in a
substantive paper or written report containing significant analysis and interpretation of study results. Open to all
qualified seniors and graduate students with consent of supervising instructor. Instructor: Schwartz-Bloom. 3 units.
211. Research Independent Study in Science Education. Individual research in a field of science education (with
reference to pharmacology) at the precollege/college level, under the supervision of a faculty member, resulting in a
substantive paper or written report containing significant analysis and interpretation of study results. Open to all
qualified seniors and graduate students with consent of supervising instructor. Instructor: Schwartz-Bloom. 1 unit.
233. Essentials of Pharmacology and Toxicology. Drug absorption, distribution, excretion, and metabolism. Structure
and activity relationships; drug and hormone receptors and target cell responses. Consent of instructor required.
Prerequisite: introductory biology; Chemistry 151L; Mathematics 31 and 32. Instructor: Slotkin and staff. 4 units.
234. Interdisciplinary Approach to Pharmacology. Several model systems (cancer, immunological disorders, and
infectious diseases) will be used to explore the molecular, biochemical, and physiological basis of drug action.
Instructors: Rathmell, Wang, or Whorton. 4 units.
235. Interdisciplinary Approaches to Pharmacology Part II. Several model systems (CNS, cardiovascular, and
infectious diseases) will be used to explore the molecular biochemical, and physiological basis of drug action. Instructor:
Whorton. 4 units.
254. Mammalian Toxicology. Principles of toxicology as related to humans. Emphasis on the molecular basis for toxicity
of chemical and physical agents. Subjects include metabolism and toxicokinetics, toxicologic evaluation, toxic agents,
target organs, toxic effects, environmental toxicity, management of poisoning, epidemiology, risk assessment, and
regulatory toxicology, Prerequisite: introductory biology, and Chemistry 151L, or consent of instructor. Instructor:
Abou-Donia and staff. 4 units.
280. Student Seminar in Pharmacology. Preparation and presentation of seminars to students and faculty on topics of
broad interest to pharmacology. Required of all pharmacology graduate students. Instructor: Wang and Thiele. 2 units.
297. Research Independent Study. Individual research in a pharmacology-related area under the supervision of a faculty
member, resulting in a substantive paper or written report containing significant analysis and interpretation of the study
results. Open to juniors and seniors with consent of supervising instructor. Instructor: Staff. 3 units.
298. Research Independent Study. Individual research in a pharmacology-related area under the supervision of a faculty
member, resulting in a substantive paper or written report containing significant analysis and interpretation of the study
results. Open to juniors and seniors with consent of supervising instructor. Instructor: Staff. 3 units.
299. Research Independent Study. Individual research in a pharmacology-related area under the supervision of a faculty
member, resulting in a substantive paper or written report containing significant analysis and interpretation of the study
results. Open to juniors and seniors who have already taken Pharmacology 297 and 298, with consent of supervising
instructor. Instructor: Staff. 3 units.
For Graduate Students Only
314. Integrated Case Studies in Toxicology. 1 unit. C-L: see Environment 314
315. Focused Topics in Toxicology. 1 unit. C-L: see Environment 315
333. Statistics for Basic Biomedical Scientists. The use and importance of statistical methods in laboratory science, with
an emphasis on the nuts and bolts of experimental design, hypothesis testing, and statistical inference. Central tendency
and dispersion, Gaussian and non-Gaussian distributions, parametric and nonparametric tests, uni- and multivariate
designs, ANOVA and regression procedures. Ethical issues in data handling and presentation. Student presentations in
addition to formal lectures. Intended for third-year graduate students. Instructor: Slotkin. 2 units. C-L: Neurobiology
333
347. Seminar in Toxicology. A weekly research seminar throughout the year is required of participants in the Toxicology
Program. Students, faculty, and invited speakers present their findings. Instructor: Levin. 1 unit.
Departments, Programs, and Course Offerings 179