SOUCHES AFRICAINES DU VIRUS DE LA ROUGEOLE : ETUDE ...

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A ) Hunan.CHN/93/7 Beijing.CHN/94/1 Yaounde.CAE/9.01 0.01 Genotype H1 H2 86 Yaounde.CAE/8.01 Yaounde.CAE/6.01 Yaounde.CAE/5.01 96 81 Ibadan.NIE/11.98 Ibadan.NIE/97/1 Ibadan.NIE/10.98/3 B3. 1 Khartoum.SUD/28.00/6 Khartoum.36.97/1 97 Ibadan.NIE/9.98/3 Ibadan.NIE/8.98/10 96 94 New York.USA/94 Gambia/93 (G954) B3. 2 Lyon.FRA/94 (Lys-1) Yaounde.CAE/83/14 B1 Libreville.GAB/84/96 MVs/Madrid.SPA/94-SSPE Edmonston-wt.USA/54 B2 F A 90 Madrid.SPA/79 “JM”USA/77 Braxator.DEU/71 Johannesburg.SOA/88/1 C1 C2 E D2 80 Victoria.AUS/16.85 Manchester.UNK/30.94 Palau.BLA/93 Montreal.CAN/89 Chicago.USA/89/1 New-Jersey.USA/94/1 Bristol.UNK/74 Berkeley.USA/83 D7 D8 D5 D4 D3 D6 D1 G1 98 MVs.Victoria.AUS/24.99 Amsterdam.NET/49.97 g3 G2 Fig 1 : Phylogenetic analysis of African measles isolates based on NP gene (A) and HA gene (B). Significant bootstrap values (>80%) are indicated. 105
106 0.005 100 82 100 86 98 New York.USA/94 91 98 98 100 98 98 100 93 100 100 100 97 88 Khartoum.SUD/28.00/6 Berkeley.USA/83 Hunan.CHN/93/7 Beijing.CHN/94/1 Bristol.UNK/74 Johannesburg.SOA/88/1 New-Jersey.USA/94/1 Chicago.USA/89/1 Palau.BLA/93 Montreal.CAN/89 Victoria.AUS/16.85 Manchester.UNK/30.94 Braxator.DEU/71 “JM”USA/77 Gambia/93 (G954) Lyon.FRA/94 (LYS-1) Ibadan.NIE/9.98/3 IbadanNIE/8.98/10 Yaounde.CAE/5.01 Yaounde.CAE/9.01 Yaounde.CAE/8.01 Yaounde.CAE/6.01 Ibadan.NIE/10.98/3 Ibadan.NIE/11.98 Khartoum.SUD/36.97/1 Yaounde.CEA/83/14 Libreville.GAB/84/96 Madrid.SPA/79 Edmonston-wt.USA/54 MVs/Madrid.SPA/94-SSPE MVs.Victoria.AUS/24.99 Amsterdam.NET/49.97 Ibadan.NIE/97/1 B3.1 B3.2 B) Genotype
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UNIVERSITE JOSEPH FOURIER-GRENOBLE
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Je remercie le Dr Florence PRADEL e
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II.3 2. Les nouveaux vaccins……
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VI.3. La rougeole au Cameroun : Etu
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CHAPITRE I : LE VIRUS DE LA ROUGEOL
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I.Le virus de la rougeole 2. Classi
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I.Le virus de la rougeole 3. Struct
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I.Le virus de la rougeole 5. Cycle
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I.Le virus de la rougeole 5. Cycle
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Récepteur cellulaire Etat natif H
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I.Le virus de la rougeole 6. Pathol
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II. La vaccination 1. Les vaccins i
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II. La vaccination 2. Les vaccins v
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Figure 6 : Souches vaccinales utili
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II. La vaccination 3. Les nouvelles
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II. La vaccination 3. Les nouvelles
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II. La vaccination 4. Position actu
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CHAPITRE III. ETUDES EPIDEMIOLOGIQU
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III. Etudes épidémiologiques 1. I
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III. Etudes épidémiologiques 2. P
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III. Etudes épidémiologiques 4. R
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Page 61 and 62: IV. Epidémiologie moléculaire du
Page 73 and 74: V. La rougeole en Afrique 1. La rou
Page 79 and 80: Figure 8: Répartition des cas de r
Page 83 and 84: VI. Etude des souches Africaines du
Page 89 and 90: VI.1.4. Article 1 : Adaptation des
Page 91 and 92: 1506 NOTES J. VIROL. FIG. 1. MV inf
Page 93 and 94: 1508 NOTES J. VIROL. FIG. 3. Flow c
Page 97 and 98: Figure 9 : Répartition géographiq
Page 103 and 104: Measles virus strains circulating i
Page 105 and 106: In 1983, measles viruses isolated i
Page 107 and 108: obtained for the two 1983 isolates
Page 109 and 110: easons. The available data for meas
Page 111: Malvoisin E, Wild TF. 1990. Contrib
Page 115 and 116: Table 1 : African measles strains u
Page 117 and 118: VI.3. LA ROUGEOLE AU CAMEROUN : ETU
Page 129 and 130: CHAPITRE VII. DISCUSSION 122
Page 131 and 132: VII. Discussion 1. Interaction viru
Page 133 and 134: VII. Discussion 1. Interaction viru
Page 135 and 136: VII. Discussion 2. Epidémiologie C
Page 137 and 138: VII. Discussion 2. Epidémiologie f
Page 139 and 140: CHAPITRE VIII. CONCLUSION ET PERSPE
Page 141 and 142: ANNEXES 134
Page 143 and 144: Consensus ATATCCATCA TGGGTCTCAA GGT
Page 145 and 146: Consensus MTEIYDFDKS AWDIKGSIAP IQP
Page 147 and 148: Consensus ATGTCACCGC AACGAGACCG GAT
Page 149 and 150: Consensus MSPQRDRINA FYKDNPYPKG SRI
Page 151 and 152: Consensus MGLKVNVSAI FMAVLLTLQT PAG
Page 153 and 154: Aaby, P., Bukh, J., Lisse, I. M. &
Page 155 and 156: Bouteille, M., Fontaine C., Vedrenn
Page 157 and 158: Davenport, M. P., Quinn, C. L., Chi
Page 159 and 160: Foege, W. (1971). Measles vaccinati
Page 161 and 162: Griffin, D. E., Ward, B. J., Jaureg
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Holt, E. A., Moulton, L. H., Siberr
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Kok, P. W., Kenya, P. R. & Ensering
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Markowitz, L. E., Albrecht, P., Rho
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Norrby, E., Enders-Ruckles, G. & Me
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Poland, G. A., Jacobson, R. M., Col
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Siber, G. R., Werner, B. G., Halsey
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Truong, A. T., Mulders, M. N., Gaut
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WHO, World Health Organisation, Exp
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TABLE DES ILLUSTRATIONS Figure 1. R
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Abstract Despite the availability o
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