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nutrição, imunidade e infecção na infância - Nestlé

nutrição, imunidade e infecção na infância - Nestlé

nutrição, imunidade e infecção na infância - Nestlé

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Pesquisa futura: Trabalho adicio<strong>na</strong>l é necessário para (i) delinear asalterações nos mecanismos de controle central e periférico durante a<strong>infecção</strong>; (ii) para determi<strong>na</strong>r se esses controles diferem conforme o tipode <strong>infecção</strong> e (iii) para explorar maneiras de modificar as viasanorexíge<strong>na</strong>s periféricas com possíveis efeitos benéficos sobre a ingestãode alimento sem comprometer a capacidade do hospedeiro de responderà <strong>infecção</strong>.Bibliografia1. Dunn AJ, Wang J. Cytokine effects on CNS biogenic amines. Neuroiimuno-modulation1995;2:319-28.2. Conn CA, Me Clellan JL, Maassab JF, Smitka CW, Majde JA, Kluger MJ. Cytokinesand the acute phase response to influenza virus in mice. Am J Physiol 1995; 268;R78-84.3. Ballinger AB, Kelly P, Hallyburton E, Besser R, Farthing MJG. Plasma leptin inchronic inflammatory bowel disease and HIV: implications for the pathogenesis ofanorexia and weight loss. Clinical Science 1998;94:479-83.4. Sonti G, Ilyn SE, Plata-Salaman CR. Anorexia induced by cytokine interactions atpathophysiological concentrations. Am J Physiol 1996;270;R1394-402.5. Ballinger AB, El-Haj T,,Corder R, Williams G, Farthing MJG. The role of hypothalamicneuropeptide Y in anorexia associated with experimental colitis. Gastroenterology1999, in press.6. El-Haj T, Ballinger AB, Perrett D, Williams G, Farthing MJG. Increasing activity ofhypothalamic 5-HT neuro<strong>na</strong>l activity in a model of colitis-associated anorexia.Gastroenterology 1999, in press.37

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