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CHAPTER 11 The Trematodes

Operculum

Thickened rim

around operculum

(called shoulders)

Developed

miracidium

Small knob

B

A

Average size: 30 m by 15 m

FIGURE 11-5 A, Clonorchis sinensis egg. B, Clonorchis sinensis egg. (B from Mahon CR, Lehman DC, Manuselis G:

Textbook of diagnostic microbiology, ed 4, St Louis, 2011, Saunders.)

encysted metacercariae. Maturation of the immature

flukes takes place in the liver. The adult

worms take up residence in the bile duct.

Epidemiology

C. sinensis is endemic in areas of the Far East,

including China, especially the northeast portions,

Taiwan, Korea, Vietnam, and Japan. Reservoir

hosts include fish-eating mammals, dogs,

and cats. More than 35 million people are

infected, and the numbers have tripled to 15

million in China alone in the last decade. Much of

this increase may be the result of aquaculture.

Clinical Symptoms

Average size: 2 cm by 0.5 cm

FIGURE 11-6 Clonorchis sinensis adult.

Asymptomatic. Light infections typically

occur without any obvious symptoms.

Clonorchiasis. Persons infected with a heavy

worm burden often experience symptoms that

include fever, abdominal pain, eosinophilia, diarrhea,

anorexia, epigastric discomfort, and occasional

jaundice. Enlargement and tenderness of

the liver and leukocytosis may also occur. Liver

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