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APPENDIX A

Glossary

larva (pl., larvae) Juvenile stage of a worm. Singular,

larva.

larval Pertaining to larvae.

leishmaniasis General and collective name for the

diseases caused by any organisms of the genus

Leishmania.

lymphadenopathy Enlargement of the lymph

nodes.

macrogametocyte (pl., macrogametocytes)

Female sex cell that occurs in the malarial life

cycle.

macronucleus Large, often kidney-bean shaped

nucleus found in Balantidium coli. The macronucleus

shape may vary.

malaria, malarial Name for the disease caused by

infection with Plasmodium spp.; pertaining to

malaria.

malarial malaria Name for the form of malaria

caused by plasmodium malarial.

malignant tertian malaria Disease caused by

Plasmodium falciparum that develops following

a relatively short incubation period of 7 to 10

days. Daily episodes of chills and fever, as well

as severe diarrhea, nausea, and vomiting, rapidly

develop, followed by cyclic paroxysms, which

occur every 36 to 48 hours. A fulminating

disease results and the intestinal symptoms

(nausea, vomiting, diarrhea) mimic those seen in

malignant infections—hence, the name malignant

tertian malaria. It is also known as black

water fever.

mature schizont (pl., schizonts) Fully developed

stage of the asexual sporozoa trophozoite (i.e.,

Plasmodium spp.) characterized by the presence

of mature merozoites.

Maurer’s dot (pl., dots) A dark-red staining,

irregular to comma-shaped dot located in the

cytoplasm of red blood cells infected with Plasmodium

falciparum; also known as Maurer’s

clefts. Maurer’s dots tend to have a more bluish

tint after Giemsa staining than Schüffner’s dots.

median body (pl., median bodies) Slightly rodlike-shaped

structure (resembling a comma)

located in the posterior portion of Giardia intestinalis

trophozoites and cysts. Although they are

believed to be associated with energy or metabolism,

or with supporting the organism’s posterior

end, their exact function is unclear.

megacolon Enlargement of the colon seen in

infections caused by the presence of Trypanosoma

cruzi.

megaesophagus Enlargement of the esophagus

seen in infections caused by the presence of Trypanosoma

cruzi.

merozoite (pl., merozoites) Contents of the fully

developed stage of the asexual Sporozoa trophozoite

(i.e., Plasmodium spp., the mature schizont)

produced in both the liver cells and RBCs

and capable of initiating infection in previously

healthy red blood cells.

metacercaria (pl., metacerariae) Encysted form

of the fluke life cycle; occurs on water plants or

in the second intermediate host, such as fish,

crabs, or crayfish. It is the infective stage for

humans.

metamorphosis Transition of one developmental

stage into another. In the case of the arthropods,

the nymphs resemble the adults morphologically

in incomplete (simple) metamorphosis. In complete

metamorphosis, the developmental stages

(larvae and pupa) do not morphologically resemble

the adults.

Metazoa Subkingdom that consists of multicellular

organisms, including parasitic worms.

microfilaria (pl., microfilariae) The embryonic

stage of a filarial parasite. Adult female filarial

worms lay live microfilariae; there is no known

egg stage.

microgametocyte (pl., microgametocytes) Male

sex cell that occurs in the malarial life cycle.

micron (pl., microns) Measuring unit of parasites;

also known as a micrometer; one thousandth

(10 −3 ) of a millimeter or one millionth (10 −6 ) of

a meter. Microns are abbreviated as µ or µm.

micronucleus Small dotlike nucleus found in Balantidium

coli; often difficult to see, even in

stained preparations.

miracidium First-stage larva of flukes that emerge

from the egg in fresh water, equipped with cilia,

which aid in movement. This is the infective

stage for the first intermediate host (snail).

mode of transmission (pl., modes of transmission)

The means whereby a parasite gains entry

into an unsuspecting host.

Montenegro skin test A test similar to that of the

tuberculin skin test used for screening large populations

at risk for contracting Leishmania spp.

infections.

mucocutaneous Refers to disease that causes

lesions of the skin and mucous membranes, specifically

in the oral and nasal mucosa regions of

the body.

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