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CHAPTER 12 Artifacts and Confusers

Average size: up to 150 m

FIGURE 12-4 Vegetable cell.

FIGURE 12-6 Vegetable spiral, Iron hematoxylin stain,

1000X. Arrow indicates a vegetable spiral artifact. (Courtesy

of Carolina Biological Supply Company.)

FIGURE 12-5 Vegetable spiral.

VEGETABLE CELLS

Vegetable cells may easily be confused with helminth

eggs (Fig. 12-4). These cells are typically

large and roundish oval to irregularly round in

shape and may measure up to 150 µm in size.

Thick cell walls are usually present. The interior

portion of vegetable cells is unorganized and

often appears to consist primarily of large

vacuoles.

VEGETABLE SPIRALS

Vegetable spirals often resemble helminth larvae

in their shape and size (Figs. 12-5 and 12-6).

Unlike helminth larvae, however, vegetable

spirals do not have a head or tail region. Vegetable

spirals are readily distinguished from parasitic

forms by their ladder-like appearance. The

ladder consists of a series of rungs that are spaced

closely together.

FIGURE 12-7 Charcot-Leyden crystal.

Quick Quiz! 12-2

Which of the following characteristics can help differentiate

vegetable spirals from helminth larvae?

(Objective 11-1)

A. Presence of head or tail region

B. Ladder-like appearance

C. Characteristic worm shape

D. Length of spiral

CHARCOT-LEYDEN CRYSTALS

Of all of the confusers and artifacts discussed in

this chapter, Charcot-Leyden crystals have the

most clinical significance (Fig. 12-7). They are

typically found in stool or sputum specimens and

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