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CHAPTER 3 The Amebas

TABLE 3-10

choice for identifying E. nana trophozoites and

cysts is stool examination.

Epidemiology

E. nana is found primarily in warm, moist regions

of the world, as well as other areas in which poor

hygiene and substandard sanitary conditions

exist. Food or drink contaminated with E. nana

infective cysts serve as the major sources of parasite

transmission.

Clinical Symptoms

E. nana infections are usually asymptomatic.

Treatment

E. nana is considered a nonpathogen. Treatment

is generally not indicated.

Prevention and Control

Endolimax nana Cyst:

Typical Characteristics at

a Glance

Parameter

Description

Size range 4-12 µm

Shape

Spherical, ovoid, ellipsoid

Number of nuclei One to four; four most

common

Karyosome

Large, blotlike, usually

central

Peripheral chromatin Absent

Cytoplasm

Granular and vacuolated

Cytoplasmic inclusions Chromatin granules

Nondescript small mass

Diffuse glycogen mass in

young cysts

As with other intestinal amebas, protection of

food and drink from flies and cockroaches is

essential to halt the spread of E. nana infections.

In addition, good sanitation and personal hygiene

practices are also crucial preventive measures.

Quick Quiz! 3-15

The appearance of an E. nana karyosome is usually

which of the following? (Objective 3-9A)

A. Granular

B. Large and round

C. Small and round

D. Blotlike

Quick Quiz! 3-16

Which of the following statements is true regarding

E. nana? (Objectives 3-2 and 3-7)

A. E. nana is found primarily in cold regions of the

world.

B. E. nana is prevalent in areas in which poor hygiene

and substandard sanitary conditions exist.

C. E. nana is considered as a human pathogen, so

treatment is mandatory.

D. Humans can obtain protection from E. nana via

vaccination.

Iodamoeba bütschlii

(eye-o’doh-mee’buh/bootch’lee-eye)

Common associated disease or condition names:

None (considered as a nonpathogen).

Morphology

Trophozoites. The trophozoites of Iodamoeba

bütschlii average 12 to 18 µm but may vary from

8 to 22 µm in size (Fig. 3-16; Table 3-11). These

trophozoites characteristically exhibit progressive,

sluggish motility. The single nucleus consists

of a large, usually central karyosome surrounded

by refractive achromatic granules, which are

often not distinct, even when the trophozoite is

permanently stained. Peripheral chromatin is

absent. The coarsely granular and vacuolated

cytoplasm may contain bacteria, yeast cells, or

other debris.

Cysts. I. bütschlii cysts typically measure 8 to

12 µm in size. Some cysts may be as small as

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