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CHAPTER 4 The Flagellates

A. Identify and describe the function of key

differential characteristic structures.

B. Identify each responsible flagellate

organism by category, scientific name,

common name, and morphologic form,

with justification when indicated.

C. Identify the associated symptoms,

diseases, and conditions associated with

the responsible parasite.

D. Construct a life cycle associated with

each flagellate parasite present that

includes corresponding epidemiology,

route of transmission, infective stage,

and diagnostic stage(s).

E. Propose each of the following related to

controlling and preventing flagellate

infections:

1. Treatment options

2. Prevention and control plan

F. Determine the specimen of choice and

alternative specimen types, where

appropriate, as well as appropriate

laboratory diagnostic technique for the

recovery of each flagellate.

G. Recognize sources of error, including but

not limited to, those involved in specimen

collection, processing, and testing and

propose solutions to remedy them.

H. Interpret laboratory data, determine

specific follow-up tests to be done, and

predict the results of those tests.

I. Determine additional morphologic

forms, when appropriate, that may also

be detected in clinical specimens.

4-11. Compare and contrast the similarities and

differences between:

A. The flagellates covered in this chapter

B. The flagellates covered in this chapter

and the other parasites covered in this

text

4-12. Describe the standard, immunologic, and

new laboratory diagnostic approaches for

the recovery of flagellates in clinical

specimens.

4-13. Given prepared laboratory specimens, and

with the assistance of this manual, the

learner will be able to:

A. Differentiate flagellate parasites from

artifacts.

B. Differentiate the flagellate organisms

from each other and from the other

appropriate categories of parasites.

C. Correctly identify each flagellate parasite

by scientific and common names and

morphologic form, based on its key

characteristic structure(s).

CASE STUDY 4-1

UNDER THE MICROSCOPE

A 30-year-old man, Bryan, visited his physician complaining

of cramping, frequent diarrhea, and weight loss. Patient

history revealed that Bryan was a frequent back country

hiker and camper who did not always filter his drinking

water while on his camping trips. The physician on duty

ordered a series of stool samples for ova and parasite

(O&P) examination.

Questions for Consideration

1. Indicate how Bryan might have come into contact with

parasites and identify the factors that likely contributed

to this contact. (Objective 4-10D)

2. Name two other symptoms associated with parasitic

infections that people like Bryan may experience.

(Objective 4-10C)

3. How should the physician order the O&P analysis in terms

of frequency of specimen collection? (Objective 4-10F)

FOCUSING IN

Flagellates belong to the phylum Protozoa and

are members of the subphylum Mastigophora.

The flagellates can be categorized into two

groups, intestinal and atrial. This chapter

describes the morphologic features, laboratory

diagnosis, life cycle, epidemiology, clinical symptoms,

treatment, and prevention and control of

eight members of the flagellates, each of which is

known to infect humans.

MORPHOLOGY AND LIFE

CYCLE NOTES

Movement of the flagellates is accomplished by

the presence of whiplike structures known as

flagella in their trophozoite form. It is this

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