Biological - NIH Office of Science Education - National Institutes of ...
Biological - NIH Office of Science Education - National Institutes of ...
Biological - NIH Office of Science Education - National Institutes of ...
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Key aspects <strong>of</strong> case studies and<br />
answers to discussion questions<br />
CASE HISTORY 1:<br />
Key aspects<br />
Diagnosis<br />
Matching symptoms<br />
From Primary Information<br />
• Excessive daytime sleepiness<br />
• Possible genetic connection through mother<br />
• Vivid dreams<br />
• Inability to move after waking in the morning<br />
• Weakness associated with emotion<br />
Narcolepsy<br />
• Excessive daytime sleepiness<br />
• Cataplexy<br />
• Sleep paralysis<br />
After reading Secondary Information<br />
Is your initial diagnosis confirmed?<br />
If no, what is your new diagnosis?<br />
If no, what caused you to change your mind?<br />
Recommended treatment<br />
Expected outcome<br />
(effect <strong>of</strong> treatment on patient symptoms)<br />
Answers will vary.<br />
Answers will vary.<br />
Entering REM sleep early is consistent with vivid<br />
dreams and hypnagogic hallucinations characteristic<br />
<strong>of</strong> narcolepsy.<br />
Medication and lifestyle changes such as<br />
frequent napping<br />
Control <strong>of</strong> most symptoms<br />
ANSWERS TO DISCUSSION QUESTIONS<br />
1. Why is it important to consider that the patient’s mother reportedly<br />
had a similar problem?<br />
It establishes the possibility <strong>of</strong> a genetic link for the patient’s disorder.<br />
Genetics is implicated in some sleep disorders and not others. In<br />
fact, a gene responsible for narcolepsy in dogs has been discovered.<br />
2. Of what significance is it that this patient’s sleepiness began during<br />
her teen years?<br />
The excessive sleepiness characteristic <strong>of</strong> narcolepsy usually begins<br />
during a person’s teen years or early twenties.<br />
109<br />
Student Lesson 4