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Biological - NIH Office of Science Education - National Institutes of ...

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Key aspects <strong>of</strong> case studies and<br />

answers to discussion questions<br />

CASE HISTORY 1:<br />

Key aspects<br />

Diagnosis<br />

Matching symptoms<br />

From Primary Information<br />

• Excessive daytime sleepiness<br />

• Possible genetic connection through mother<br />

• Vivid dreams<br />

• Inability to move after waking in the morning<br />

• Weakness associated with emotion<br />

Narcolepsy<br />

• Excessive daytime sleepiness<br />

• Cataplexy<br />

• Sleep paralysis<br />

After reading Secondary Information<br />

Is your initial diagnosis confirmed?<br />

If no, what is your new diagnosis?<br />

If no, what caused you to change your mind?<br />

Recommended treatment<br />

Expected outcome<br />

(effect <strong>of</strong> treatment on patient symptoms)<br />

Answers will vary.<br />

Answers will vary.<br />

Entering REM sleep early is consistent with vivid<br />

dreams and hypnagogic hallucinations characteristic<br />

<strong>of</strong> narcolepsy.<br />

Medication and lifestyle changes such as<br />

frequent napping<br />

Control <strong>of</strong> most symptoms<br />

ANSWERS TO DISCUSSION QUESTIONS<br />

1. Why is it important to consider that the patient’s mother reportedly<br />

had a similar problem?<br />

It establishes the possibility <strong>of</strong> a genetic link for the patient’s disorder.<br />

Genetics is implicated in some sleep disorders and not others. In<br />

fact, a gene responsible for narcolepsy in dogs has been discovered.<br />

2. Of what significance is it that this patient’s sleepiness began during<br />

her teen years?<br />

The excessive sleepiness characteristic <strong>of</strong> narcolepsy usually begins<br />

during a person’s teen years or early twenties.<br />

109<br />

Student Lesson 4

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