Bipolar Disorders: Mixed States, Rapid-Cycling, and Atypical Forms

227 Acute and transient psychotic disorderTable 9.13 Significant differences between acute and transient psychotic disorder (ATPD:polymorphic subtype) and all mixed statesATPD(n ¼ 25)n(%)All mixedstates (n ¼ 48)n(%)Statisticalanalysis aGenderFemale 20(80.0) 26(54.2) P ¼ 0.030Male 5(20.0) 22(45.8)Age at onset (years) 34.5 8.0 31.8 11.3 NSbDisability pension at follow-up2(8.0) 22(55.0) P ¼ 0.001Number of suicide attempts 0.40 0.65 1.23 1.8 0.028Premorbid personality b n ¼ 22 n ¼ 34Obsessoid 5(22.7) 16(47.1) NSSthenic/highly self-confident 5(22.7) 12(35.3) NSAsthenic/low self-confident 10(45.5) 4(11.8) P ¼ 0.004Nervous-tense 2(9.1) 2(5.9) NSbDimensional personality scores (NEO-FFI) N ¼ 19 N ¼ 42Neuroticism 1.88 0.50 2.09 0.67 NSExtroversion 2.12 0.62 2.06 1.90 NSOpenness to experiences 2.14 0.41 2.16 2.24 NSAgreeableness 2.66 0.42 2.73 2.48 NSConscientiousness 2.80 0.41 2.76 2.39 P ¼ 0.006a 2 -test or Fisher’s exact test, two-tailed for categorical variables, t-test for continuous variables.b Reduced n, because some patients could not be followed up or information was insufficient torate this item.NEO-FFI, NEO Five-Factor Inventory.ATPD versus the groups of bipolar affective mixed, bipolar schizoaffective mixed, bipolaraffective non-mixed, and non-mixed bipolar schizoaffective disordersFinally, we also included the non-mixed subtypes of bipolar affective and schizoaffectivedisorders (i.e., patients who never during the course of their illnessexperienced an episode that qualified as mixed episodes). The results of thesecomparison s, now compr ising five groups, a re provided in Table 9.1 4asand9.14b.For some of the comparisons, the statistical power was quite small due to thelow number of patients in some subgroups. We therefore calculated the comparisonsfor the combined groups of mixed and non-mixed bipolar disorders (affectiveand schizoaffective). The results are given in Table 9.15. Generally, theyconfirm the picture given in the preceding tables.