Bipolar Disorders: Mixed States, Rapid-Cycling, and Atypical Forms

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Table 9.14a Significant differences between acute and transient psychotic disorder (ATPD), affective mixed states, and schizoaffective mixed states(part 1)Bipolaraffectivemixed states(BAD-MIX:n ¼ 16)Bipolarschizoaffectivemixed states(BSAP-MIX:ATPD(n ¼ 39)n (%) n (%) n ¼ 32) n (%)Bipolaraffective –never mixed(BAD-NOMIX:n ¼ 30)Bipolarschizoaffectivenever mixed(BSAP-NOMIX:n ¼ 48)Statistical analysis aGenderFemale 30(76.9) 11(68.8) 15(46.9) 16(51.6)21(42.9) ATPD > BSAP-NOMIXATPD > BAD-NOMIX ATPD > BSAP-MIX Male 9(23.1) 5(31.3) 17(53.1) 15(48.4) 28(57.1)Age at onset 35.4 11.4 37.0 11.3 29.3 10.5 35.9 12.3 28.2 10.3 ATPD > BSAP-NOMIXBSAP-NOMIX > BAD-NOMIX bDisabilitypension atfollow-upn ¼ 39 n ¼ 14 n ¼ 26 n ¼ 26 n ¼ 424(10.3) 5(35.7) 17(65.4) 17(65.4) 34(81.0) ATPD < BAD-MIX ATPD < BSAP-MIX ATPD < BAD-NOMIX ATPD < BSAP-NOMIX BAD-MIX > BSAP-NOMIX a Only pairwise comparisons with significant differences (2 -test or Fisher’s exact test, two-tailed) are shown. P < 0.05; P < 0.01; P < 0.001; NS, no significance.b Differences overall significant in ANOVA (P ¼ 0.002), pairwise comparisons given are significant on trend level (P < 0.1) in Scheffé test.
Table 9.14b Significant differences between acute and transient psychotic disorder (ATPD), affective mixed states, and schizoaffective mixed states(part 2)Bipolaraffective mixedstates (BAD-MIX)Bipolarschizoaffectivemixed states(BSAP-MIX)Bipolaraffective –never mixed(BAD-NOMIX)Bipolarschizoaffectivenever mixed(BSAP-NOMIX)ATPDn (%) n (%) n (%) Statistical analysis aPremorbidpersonality c n ¼ 35 n ¼ 11 n ¼ 23 n ¼ 13 n ¼ 20Obsessoid 8(22.9) 5(45.5) 11(47.8) 8(61.5) 12(60.0) ATPD < BSAP-MIX ATPD < BSAP-NOMIX ATPD < BAD-NOMIX Sthenic/highlyself-confident 5(14.3) 5(45.5) 7(30.4) 5(38.5) 4(20.0) ATPD < BSAP-MIX Asthenic/lowself-confident 19(54.3) 0 4(17.4) 0 3(15.0)ATPD > BSAP-MIX ATPD > BAD-MIX ATPD > BAD-NOMIX ATPD > BSAP-NOMIX Nervous-tense 3(8.6) 1(9.1) 1(4.3) 0 1(5.0) NSDimensionalpersonalityscores (NEO-FFI)n ¼ 32 n ¼ 15 n ¼ 27 n ¼ 27 n ¼ 41
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Bipolar DisordersMixed States, Rapi
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ContentsList of contributorsPreface
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ContributorsValadeta Ajdacic PhDPsy
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ixList of contributorsAlexia E. Kou
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PrefaceBipolar disorders have a lon
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2 A. Marneros and F. K. Goodwinold
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4 A. Marneros and F. K. GoodwinFig.
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6 A. Marneros and F. K. GoodwinThe
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8 A. Marneros and F. K. GoodwinFig.
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16 A. Marneros and F. K. Goodwin(19
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18 A. Marneros and F. K. GoodwinBip
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26 A. Marneros and F. K. Goodwinbou
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28 A. Marneros and F. K. GoodwinAno
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30 A. Marneros and F. K. GoodwinTab
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32 A. Marneros and F. K. GoodwinBip
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38 A. Marneros and F. K. GoodwinAki
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40 A. Marneros and F. K. GoodwinDil
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42 A. Marneros and F. K. GoodwinMar
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44 A. Marneros and F. K. GoodwinPri
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46 G. Perugi and H. S. AkiskalTable
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50 G. Perugi and H. S. AkiskalDepre
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52 G. Perugi and H. S. Akiskalwith
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54 G. Perugi and H. S. Akiskal3020.
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59 Longitudinal perspective of mixe
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3Rapid-cycling bipolar disorder1 2O
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63 Rapid-cycling bipolar disorderPs
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65 Rapid-cycling bipolar disorderOn
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67 Rapid-cycling bipolar disorderBr
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69 Rapid-cycling bipolar disorderin
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71 Rapid-cycling bipolar disorderLa
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73 Rapid-cycling bipolar disorderre
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75 Rapid-cycling bipolar disorderCo
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77 Rapid-cycling bipolar disorderDe
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79 Rapid-cycling bipolar disorderan
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81 Rapid-cycling bipolar disorderTa
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83 Rapid-cycling bipolar disorderRE
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85 Rapid-cycling bipolar disorderJo
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87 Rapid-cycling bipolar disorderde
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89 Bipolar I and bipolar II: a dich
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101 Bipolar I and bipolar II: a dic
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5Recurrent brief depression as an i
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111 Recurrent brief depressionRecur
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113 Recurrent brief depressionbeen
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115 Recurrent brief depressioncorre
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117 Recurrent brief depressionThere
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Chronic 4.8 18.2 9.1 10 NCRapid-cyc
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121 Recurrent brief depressionTable
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123 Recurrent brief depressionPreva
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125 Recurrent brief depressionWe fo
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127 Recurrent brief depressionREFER
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129 Recurrent brief depressionMarne
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6Atypical depression and its relati
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133 Atypical depression and bipolar
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7Agitated depression: spontaneous a
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159 Agitated depression: spontaneou
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Page 191 and 192: 177 Agitated depression: spontaneou
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Page 209 and 210: 195 Schizoaffective mixed statesTab
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Page 219 and 220: 205 Schizoaffective mixed statesMar
Page 221 and 222: 9Acute and transient psychotic diso
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Page 237 and 238: Table 9.10 (cont.)ATPD(n ¼ 39)Bipo
Page 239 and 240: Table 9.11 (cont.)Bipolar affective
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Page 261 and 262: Pellegrini et al. (1986) 16 23 (7-1
Page 267 and 268: 253 Atypical features of bipolarity
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279 Challenges in the genetics of b
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Table 13.1 Proportion of first-degr
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Table 13.3 Summary of recent bipola
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13q32 = 3.321q22 = 3.6Liu, C.et al.
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14Biological aspects of rapid cycli
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313 Rapid cycling and mixed statesa
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315 Rapid cycling and mixed statesa
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317 Rapid cycling and mixed statesi
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319 Rapid cycling and mixed statesC
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321 Rapid cycling and mixed statesJ
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323 Rapid cycling and mixed statesW
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325 The treatment of bipolar mixed
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16The use of atypical antipsychotic
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355 Use of atypical antipsychotic a
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17Investigational strategies: treat
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371 Investigational strategiesBIPOL
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373 Investigational strategiesinsta
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375 Investigational strategiesWhat
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377 Investigational strategiesTable
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379 Investigational strategiescateg
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381 Investigational strategiesTable
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383 Investigational strategies2. Th
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385 Investigational strategiesSachs
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387 Indexclinical course and outcom
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389 Indexdepressive mixed states 51
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391 IndexLange, J. 163learning disa
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393 Indexpsychopharmacological revo
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395 Indexmania, acute 334mixed stat
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Bipolar Disorders: Mixed States, Rapid-Cycling, and Atypical Forms

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