ʺThe WHO Does What?ʺ"The only thing I know about the World Health Organization," Isaid to Jackie after learning of Strecker's theory, "is that it's aprestigious internationally supported organization that developshealth and vaccination programs for developing countries."It suddenly seemed odd to me that over the course of my training- more than four years of college, three years of dental school, tenyears of postdoctoral research and teaching, and sixteen years ofclinical dental practice - I had learned very little about the WHO."I don't even know what's involved in becoming a WHOmember," I admitted. "The name sure imparts an air of scientificaristocracy."Eventually, as the novelty of Strecker's theory wore off, andfurther attempts at contacting Strecker by phone failed, I decidedto venture into the dungeons of Harvard's Countway MedicalLibrary to prove "the null hypothesis" - that nothing was trueabout Strecker's memorandum. [2] What I unearthed, however, inback issues of the 'WHO Chronicle' was engaging.Dozens of 'WHO Chronicle' articles that I photocopied andbrought home revealed that by 1968 the WHO had been solely incontrol of the world's experimental "biologicals" for almost twodecades. [3]"WHO has exerted a powerful influence on the quality control ofbiological substances since its very inception in 1948. . . . Since1952, when WHO interest in the establishment of internationalrequirements for such biological products began, various possiblemeasures have been examined for attempting to achieve a greaterdegree of uniformity in the quality, safety, and potency ofvaccines, antisera, etc. . . . for the control of substances ofparticular interest to WHO in relation to its mass immunizationand mass prophylaxis schemes in developing countries. . . . Themain purpose served by these international standards, referencepreparations, and reference reagents is to provide a means ofensuring worldwide uniformity in expressing the potency ofpreparations used in the prophylaxis, therapy, or diagnosis ofhuman and animal disease." [3]The coordinating body for all this work I learned was "the WHOsecretariat." The Geneva-based organization maintained severalfull-time officers and part-time consultants who worked incollaboration with several other laboratories in other countries:"The laboratories most deeply involved are the WHOInternational Laboratories for Biological Standards within thedepartments of biological standards of the Statens Seruminstitut,Copenhagen, the National Institute for Medical Research,London, and the Central Veterinary Laboratory, Weybridge,
England. Between them, these laboratories undertake the detailedwork of organizing international collaborative assays and ofholding and distributing the international biological standards andmany of the international biological reference preparations andinternational biological reference reagents. The initiative forsetting up standards and reference preparations usually comesfrom a WHO Expert Committee on Biological Standardization,which is convened annually in Geneva. It comprises recognizedexperts in the field, who serve without remuneration in theirpersonal capacity and not as representatives of governments orother bodies, together with members of the WHO secretariat.This Expert Committee also establishes the internationalstandards and reference preparations on the basis of the results ofthe international collaborative assays.""For pharmaceuticals generally, still including some biologicals,the drawing up of standards is in the hands of the ExpertCommittee on Specifications for Pharmaceutical Preparations, incollaboration with the WHO secretariat and with the help of theExpert Advisory Panel on the International Pharmacopoeia andPharmaceutical Preparations. Needless to say, close liaison isneeded between the secretariat, the Expert Committee onBiological Standardization, the Expert Committee onSpecifications for Pharmaceutical Preparations, and various otherexpert committees on, for example, antibiotics, tuberculosis,yellow fever, and cholera." [3]Another article [4] discussed the WHO's "National controlactivities" which provided advice and encouragement whencountries became "conscious of the need for controllingbiologicals." WHO helped them establish and develop their"national controllaboratories." [3]It was quickly apparent that the WHO set the standards for thedevelopment, manufacture, distribution, and administration ofessentially all pharmaceuticals used throughout the world (seefig. 2.1). [3,4]As seen in figure 2.2, they were also intimately involved indetermining which drugs should be made or remain illegal. [4]Besides assembling teams of scientists to develop, test, andstandardize new (and ancient) drugs, the WHO applied similaradministrative leadership to develop plans for attacking all thewoes of humanity. Polio, yellow fever, cholera, smallpox,whooping cough, diphtheria, tetanus, measles, anthrax, typhoid,tuberculosis, influenza, and even the common cold were alltargeted. The WHO's approach to controlling communicablediseases was spelled out by their Assistant Director-General, Dr.A. M, Payne:"Mass campaigns against certain communicable diseases requirean initial attack sustained uninterruptedly over a relatively largearea within a short period of time. . . . In smallpox, for instance,
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it up to here with this goddamn dis
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Collusion at the TopJim Goedert was
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HTLV-III publication in Francis's p
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the footprints of a retrovirus allo
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questions. Had Gallo been ashamed o
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Chapter 6Galloʹs Research Antholog
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That same year, Gallo and his cowor
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team discussed the synthesis of new
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STRINGNER S. YANGROBERT C. TINGBion
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and pellets seperated. The pellets
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[5] Gallo RC and Breitman TR. The e
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Chapter 7An Interview with Dr. Robe
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human viruses, and that the genetic
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LEN: Now, who was studying that?ROB
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father's recommendation that I coul
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LEN: OK. Explain this now. Why did
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the cancer virus. . . . Nixon was t
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LEN: OK.ROBERT: And. . . that's the
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ROBERT: If you look in the world, w
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ROBERT: They're in the references [
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started with BVV.ROBERT: Well, in t
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LEN: OK. So what happens then?ROBER
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apology Gorbachev offered Reagan ac
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slowly, and not fast. And that they
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immunodeficiency virus. Nature 1987
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GalloRC. Aminoacyl Transfer RNA Pro
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history, organization, and program