13.07.2015 Views

ICAR Technical Series no. 7 - Nitra Proc.

ICAR Technical Series no. 7 - Nitra Proc.

ICAR Technical Series no. 7 - Nitra Proc.

SHOW MORE
SHOW LESS
  • No tags were found...

Create successful ePaper yourself

Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.

Inhibition of oxytocin in repeated milkingflow ceased again 10 IU of OT was injected intrave<strong>no</strong>usly to remove theremaining milk including residual milk. Milk flow was recordedcontinuously and blood samples were collected via jugular vein cannulaat 1-min intervals from 1 min before start of milking until i.v. injection ofOT. The inhibition of milk ejection and its <strong>no</strong>rmalization during repeatedmilking in unfamiliar surroundings was <strong>no</strong>t influenced by naloxonetreatment. Therefore, any role of endoge<strong>no</strong>us opioids in the inhibition ofmilk ejection in unfamiliar surroundings could <strong>no</strong>t be demonstrated. Therewere <strong>no</strong>t differences in cortisol release during control milking and allrelocations between naloxone and control group.In addition, the effect of exoge<strong>no</strong>us ACTH 1-24(8 IU) i.v. on the release ofcortisol related to the response of cows milked in unfamiliar surroundingswas studied. Cows with totally inhibited milk ejection in response tovaginal stimulation during milking after first relocation had numericallylower cortisol levels (8.8±3.4 ng/ml; AUC/min) in response to ACTH thancows with at least partial milk ejection (38.7±12.9 ng/ml). Thus animalswith higher adrenal response to ACTH seemed to have less severeinhibition of milk ejection.ReferencesBicknell, R. J. & Leng, G. 1982 Endoge<strong>no</strong>us opiates regulate oxytocinbut <strong>no</strong>t vasopressin secretion from the neurohypophysis. Nature 298161-162von Borell, E. & Ladewig, J. 1992 Relationship between behaviourand adre<strong>no</strong>cortical response pattern in domestic pigs. Appl. Anim. Behav.Sci. 34 195-206Bruckmaier, R. M., Schams, D. & Blum, J. W. 1993 Milk removal infamiliar and unfamiliar surroundings: concentrations of oxytocin, prolactin,cortisol and β-endorphin. J Dairy Res 60 449-456Pumford, K. M., Leng, G. & Russell, J. A. 1991 Morphine actions onsupraoptic oxytocin neurones in anaesthetised rats: tolerance after i.c.v.morphine infusion. J Physiol 440 437-454Wellnitz, O., Bruckmaier, R. M. & Blum, J. W. 1997 Naloxone andadrenergic blocking agents fail to abolish central inhibition of milk ejectionin cows. J Dairy Res 64 627-631276Conference on "Physiological and technicalaspects of machine milking"

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!