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Anemia of Prematurity - Portal Neonatal

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Activity: The infant with temperature instability needs thermoregulatory support with a radiant<br />

warmer or incubator. Also, encouraging parental contact is important to ease the stress for parents<br />

and continue the bonding between the parents and child.<br />

MEDICATION Section 7 <strong>of</strong> 11<br />

Some <strong>of</strong> the antibiotics commonly used to treat neonatal sepsis syndrome are ampicillin, gentamicin,<br />

cefotaxime, vancomycin, metronidazole, erythromycin, and piperacillin. The choice <strong>of</strong> antibiotic<br />

agents should be based on the specific organisms associated with sepsis, sensitivities <strong>of</strong> the<br />

bacterial agent, and prevalent nosocomial infection trends in the nursery. Viral infections, such as<br />

herpes and fungal infections, can masquerade as bacterial infections.<br />

Drug Category: Antibiotics -- Empiric antimicrobial therapy must be comprehensive and should<br />

cover all likely pathogens in the context <strong>of</strong> the clinical setting.<br />

Drug Name<br />

Pediatric Dose<br />

Ampicillin (Marcillin, Omnipen, Polycillin, Principen, Totacillin) -- A betalactam<br />

antibiotic that is bacteriocidal for susceptible organisms, such as<br />

GBS, Listeria, non–penicillinase-producing Staphylococcus, some<br />

strains <strong>of</strong> H influenzae, and meningococci.<br />

2000 g: 2.5 mg/kg/dose IV/IM q8h<br />

IV dosage preferred; IM may be used if IV access difficult<br />

Contraindications Documented hypersensitivity<br />

Interactions<br />

Coadministration with other aminoglycosides, cephalosporins,<br />

penicillins, indomethacin, and amphotericin B may increase<br />

nephrotoxicity; because aminoglycosides enhance effects <strong>of</strong><br />

neuromuscular blocking agents prolonged respiratory depression may<br />

occur; coadministration with loop diuretics may increase auditory toxicity<br />

<strong>of</strong> aminoglycosides; possible irreversible hearing loss <strong>of</strong> varying<br />

degrees may occur (monitor regularly)<br />

Pregnancy D - Unsafe in pregnancy

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