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Anemia of Prematurity - Portal Neonatal

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Table 3. Meta-Analysis <strong>of</strong> Head-to-Head Trials With Natural Versus Synthetic Surfactants*<br />

Outcome<br />

Number <strong>of</strong><br />

trials<br />

Relative Risk<br />

(95% CI)<br />

Relative Difference<br />

(95% CI)<br />

Pneumothorax 5 0.68 (0.56, 0.83) -4.1% (-6.3%, -2.0%)<br />

BPD 4 0.97 (0.88, 1.07) -1.2% (-5.4%, -2.9%)<br />

Mortality 7 0.88 (0.76, 1.02) -2.2% (-4.7%, 0.4%)<br />

BPD or death 2 0.94 (0.87, 1.01) -3.6% (-8.0%, 0.8%)<br />

Table 4. Meta-Analysis <strong>of</strong> Clinical Trials Comparing Prophylactic Use <strong>of</strong> Surfactant Versus<br />

Rescue Treatment <strong>of</strong> Infants With Respiratory Distress Syndrome*<br />

Outcome<br />

Number<br />

<strong>of</strong><br />

trials<br />

Relative Risk<br />

(95% CI)<br />

Relative Difference<br />

(95% CI)<br />

Pneumothorax 6 0.62 (0.42, 0.89) -2.1% (-3.7%, -0.55)<br />

BPD 7 0.95 (0.81, 1.11) -0.9% (-3.5%, 1.7%)<br />

Mortality 6 0.59 (0.46, 0.76) -4.6% (-6.8%, -2.5%)<br />

BPD or death 7 0.85 (0.76, 0.95) -4.5% (-7.4%, -1.5%)<br />

Infants

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