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Anemia of Prematurity - Portal Neonatal

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PICTURES Section 10 <strong>of</strong> 11<br />

Picture 1. The lower curve indicates lungs obtained at postmortem from an infant with HMD; these<br />

lungs require far more pressure to achieve a given volume <strong>of</strong> inflation than do those obtained from<br />

an infant dying <strong>of</strong> a nonrespiratory cause. The arrows depict the inspiratory and expiratory limbs <strong>of</strong><br />

the pressure volume curves. Note the decrease in lung compliance and the higher critical opening<br />

and closing pressures respectively in the premature infant with hyaline membrane disease.<br />

Picture 2. Microscopic appearance <strong>of</strong> lungs <strong>of</strong> an infant with respiratory distress syndrome.<br />

Hematoxylin and eosin stain exhibits the presence <strong>of</strong> hyaline membranes (pink areas).<br />

Picture 3. A schematic outlining <strong>of</strong> the pathology <strong>of</strong> respiratory distress syndrome. Infants may<br />

recover completely or develop chronic lung damage, resulting in bronchopulmonary dysplasia.<br />

Picture 4. The bar chart below demonstrates the composition <strong>of</strong> lung surfactant. Of the 10%<br />

proteins, approximately 1% comprises surfactant apoproteins; the remaining proteins are derived<br />

from alveolar exudate.

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