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Anemia of Prematurity - Portal Neonatal

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POSTOPERATIVE CARE FOLLOWING SURGERY FOR BOWEL<br />

OBSTRUCTION<br />

Section 7 <strong>of</strong><br />

11<br />

Although laparotomy in the newborn period poses a significant stress to the patient, most infants<br />

recover well following successful surgical correction <strong>of</strong> the cause <strong>of</strong> the bowel obstruction.<br />

In the initial postoperative period, derangements in fluid balance, glucose metabolism, and respiratory<br />

status are common. Most infants have some third-space fluid sequestration following laparotomy and<br />

may require additional fluids in the postoperative period. Maintenance IV fluid requirements are initially<br />

at least 1.5 times normal. Nasogastric decompression until normal bowel function is established aids<br />

in the decompression <strong>of</strong> proximal bowel and facilitates healing <strong>of</strong> a bowel anastomosis. Following<br />

surgery for bowel obstruction, a transient ileus is invariably present. If postoperative bowel function is<br />

not expected to rapidly return, parenteral nutrition support is indicated. Patience before feeding a child<br />

may avoid anastomotic breakdown or postoperative obstruction.<br />

Once bowel motility is reestablished, an infant frequently demonstrates intolerance to lactose and<br />

other complex carbohydrates. A predigested or lactose-free formula may initially aid in absorption. If<br />

the terminal ileum is resected, derangements in folate metabolism and the enterohepatic circulation<br />

may be observed. Wound care is usually straightforward, and empiric antibiotics are not generally<br />

recommended after the perioperative period.<br />

LONG-TERM OUTCOMES Section 8 <strong>of</strong> 11<br />

In general, most infants with bowel obstruction who are expeditiously identified and treated have an<br />

excellent outcome. Survival usually depends on comorbidities, such as degree <strong>of</strong> prematurity,<br />

associated cardiac anomalies, and the presence <strong>of</strong> peritonitis or bowel compromise at the time <strong>of</strong><br />

surgery. The survival rate for duodenal atresia is greater than 90%. Long-term survival in patients with<br />

volvulus and jejunoileal atresia depends upon the amount <strong>of</strong> bowel remaining after resection, but an<br />

80-90% survival rate is expected. The rate <strong>of</strong> leaking anastomoses following repair <strong>of</strong> newborns with<br />

jejunoileal atresia is approximately 15%.<br />

Total parenteral nutrition and better methods for central IV access have greatly improved outcomes for<br />

neonates who undergo surgery for bowel obstruction. Often, bowel function is not established for a<br />

prolonged interval postoperatively. While total parenteral nutrition can support an infant through this<br />

period, both long- and short-term complications are observed. Short-term complications from<br />

parenteral nutrition include catheter sepsis, respiratory insufficiency, and problems related to securing<br />

central venous access. Long-term problems include cholestasis, nutritional deficiencies, and<br />

development <strong>of</strong> oral aversion.<br />

As with any laparotomy, postoperative adhesions may develop. Operative technique that avoids<br />

unnecessary manipulation <strong>of</strong> the bowel and spillage <strong>of</strong> enteric contents is perhaps the best prevention<br />

against the development <strong>of</strong> intraperitoneal scar tissue.<br />

Poor motility is <strong>of</strong>ten observed following bowel resection for obstruction. Chronic dilation <strong>of</strong> the<br />

intestinal segment proximal to the obstruction may alter normal peristalsis across that segment <strong>of</strong><br />

bowel. For example, persistent constipation and delayed intestinal transit may not resolve after relief <strong>of</strong><br />

chronic partial volvulus via Ladd procedure. Interruption <strong>of</strong> vagal neuroenteric pathways by an atresia<br />

or surgical anastomosis may also contribute to abnormal intestinal motility.<br />

Short bowel syndrome deserves special mention. Short bowel syndrome results when the remaining<br />

length <strong>of</strong> intestine cannot sustain normal absorptive functions. Normal length <strong>of</strong> the small bowel in a<br />

term infant is approximately 250 cm and in an adult is 600-800 cm. The estimated minimum jejunoileal<br />

length for sufficient bowel function in a term infant is 75 cm. Resection <strong>of</strong> more than 60% <strong>of</strong> the small<br />

bowel predisposes the child to malabsorption, resulting in failure to grow and develop normally.

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