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Bites and stings – marine<br />

STEPHEN H. THOMAS AND CIARAN J. BROWNE<br />

n Agents<br />

n Antivenom<br />

n Opioids<br />

n Magnesium<br />

n Local anesthetics<br />

n Acetic acid (vinegar)<br />

n Papain (proteolytic meat tenderizer)<br />

n Slurry of bicarbonate (baking soda)<br />

n Evidence<br />

Marine envenomation can result from discharging nematocysts (e.g. jellyfish,<br />

fire coral), puncturing spines (e.g. sea urchins, stingrays), or actual bites<br />

(e.g. blue octopus, sea snakes). The preponderance of the evidence, and<br />

thus most of this chapter’s focus,addressesjellyfish(Cnidaria or Coelenterates)<br />

envenomation.<br />

In keeping with this text’s aim, this discussion emphasizes pharmacotherapy,<br />

but one physical modality deserves mention. For most marine envenomations,<br />

hot water immersion (40–45 °C via immersion or shower, for up to<br />

90 min) can inactivate venom and achieve better pain relief than alternative<br />

approaches such as acetic acid, papain,oropioids. 1–5 One recent US series of<br />

over 100 stingray envenomations found that hot water immersion alone was<br />

sufficient for pain therapy in nearly 90% of patients. 6<br />

Whether considering physical interventions (e.g. hot water immersion),<br />

topical therapies (e.g. acetic acid dousing), or IV drug therapy (e.g. with<br />

antivenom), treatments for different marine envenomations – even those<br />

from different members of the same genus – can vary significantly. Be aware<br />

of local species, and be wary of overextrapolating clinical trials data. Although<br />

it may be impossible to identify the organism responsible for a given<br />

117

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