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Neck and back pain – spinal spondylitic<br />

syndromes<br />

MICHAEL WALTA AND STEPHEN H. THOMAS<br />

n Agents<br />

n NSAIDs<br />

n Opioids<br />

n Tricyclic antidepressants<br />

n Antiepileptics<br />

n Corticosteroids<br />

n Evidence<br />

In this chapter, neck and back pain from spinal stenosis, intervertebral disk<br />

disease, or arthritis is grouped into the category of spinal spondylitic syndromes<br />

(SSS). Acute care provider familiarity with treating SSS pain is<br />

important. Only half of medically managed patients achieve adequate outpatient<br />

analgesia, and there is little evidence to support surgical intervention<br />

for the sole purpose of obtaining pain relief. 1–4 Injection therapy (into<br />

the facet joint, epidural space, or locally) has little supporting evidence for<br />

use in SSS. 5<br />

Despite scant evidence support for their use in SSS, NSAIDs are frequently<br />

used to treat pain from these disorders. Recommendation for NSAID use in<br />

SSS, after acetaminophen (paracetamol) has failed, is based upon a presumed<br />

inflammatory component to the pain. 6,7 Since Cochrane review provides<br />

inconclusive evidence of NSAIDs’ overall efficacy in spinal pain<br />

syndromes, and since patients with SSS tend to be relatively older and<br />

more susceptible to NSAID side effects, NSAIDs should be used with caution<br />

in SSS. 8 However, NSAIDs’ common use with anecdotal success for some<br />

patients with SSS means that the acute care clinician should keep this class in<br />

mind for occasional use. COX-2 selective NSAIDs (the risks of which are<br />

addressed in the chapter on Arthritis) have not been studied in SSS. These<br />

agents appear to have little role in acute care management of SSS.<br />

273

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