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n Summary and recommendations<br />

First line: acetaminophen (initial dose 650–1000 mg PO QID), opioids (e.g.<br />

oxycodone 5–10 mg PO q4–6h)<br />

Reasonable: short course of NSAIDs (e.g. ibuprofen 600–800 mg PO TID)<br />

Pregnancy: acetaminophen (initial dose 650–1000 mg PO QID), opioids (e.g.<br />

oxycodone 5–10 mg PO q4–6h)<br />

Pediatric: acetaminophen (10–15 mg/kg PO QID), opioids (e.g. hydrocodone<br />

2.5 mg PO q4–6 h for age > 5 years)<br />

Special case:<br />

n if other agents fail and side effect risk favorable: cyclobenzaprine (5 mg PO<br />

TID) or tricyclic antidepressants (e.g. nortriptyline 50–150 mg PO qHS)<br />

References<br />

Neck and back pain – spinal spondylitic syndromes 275<br />

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transport of patients during early hours of acute myocardial infarction.<br />

Arch <strong>Int</strong>ern Med. 1989;149(2):353–355.<br />

2. Rao R. Neck pain, cervical radiculopathy, and cervical myelopathy:<br />

pathophysiology, natural history, and clinical evaluation. Instr Course Lect.<br />

2003;52:479–488.<br />

3. Kadanka Z, Mares M, Bednanik J, et al. Approaches to spondylotic cervical<br />

myelopathy: conservative versus surgical results in a 3-year follow-up study.<br />

Spine. 2002;27(20):2205–2210; discussion 2210–2211.<br />

4. Sampath P, Bendebba M, Davis JD, et al. Outcome of patients treated for<br />

cervical myelopathy. A prospective, multicenter study with independent clinical<br />

review. Spine. 2000;25(6):670–676.<br />

5. Nelemans PJ, de Bie RA, de Vet HC, et al. Injection therapy for subacute and<br />

chronic benign low back pain. Cochrane Database Syst Rev. 2000(2):CD001824.<br />

6. Mazanec D, Reddy A. <strong>Medical</strong> management of cervical spondylosis.<br />

Neurosurgery. 2007;60(1 Supp1 1):S43–S50.<br />

7. Clyman BB. Osteoarthritis: new roles for drug therapy and surgery. <strong>Int</strong>erview by<br />

Peter Pompei. Geriatrics. 1996;51(9):32–36.

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