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Chest wall trauma 171<br />

systemically administered opioids. 19,20 The success of interpleural analgesia<br />

can be affected by a number of factors, including catheter position, patient<br />

position, presence of hemothorax, location of RFs, characteristics of<br />

the local anesthetic used, and the co-administration of epinephrine. 20<br />

Because of diaphragmatic uptake of bupivacaine after interpleural administration,<br />

respiratory excursion may be affected. 21 <strong>Int</strong>erpleural catheter<br />

placement can be technically difficult and can result in symptomatic<br />

pneumothorax, intrapulmonary catheter placement, or misplacement<br />

into the chest wall or in an extrapleural plane. Local anesthetic agents<br />

are rapidly absorbed from the intrapleural space, resulting in high plasma<br />

concentration, with potential for systemic toxicity. <strong>Int</strong>erpleural instillation<br />

of local anesthetic can also cause phrenic nerve paralysis and Horner’s<br />

syndrome. 16<br />

Local anesthetics (sometimes co-administered with opioids) have also<br />

been used by the epidural administration route. <strong>This</strong> approach is associated<br />

with decreased pulmonary morbidity and mortality in patients older than<br />

60 years of age with RF. 7 Used in patients with chest wall trauma, epidural<br />

analgesia produces pain relief that is dramatic and superior to that produced<br />

by systemic opioids or other local anesthetic approaches. 5,8,11,22–24<br />

Even though the epidural route is not used by the ED provider, the evidence<br />

comparing its (favorable) performance to that of systemically administered<br />

opioids cannot be ignored. Particularly for patients with multiple RFs,<br />

epidural regimens’ advantages of improved analgesia and decreased complication<br />

rates warrant early consideration of this approach (usually after<br />

the ED setting) in patients who have been adequately resuscitated for<br />

fluid. 22<br />

Local anesthetic administration via thoracic paravertebral block entails<br />

injecting an agent such as bupivacaine alongside the thoracic vertebrae. <strong>This</strong><br />

produces multidermatomal ipsilateral somatic and sympathetic nerve blockade<br />

in contiguous thoracic dermatomes. There are few publications describing<br />

the use of this method in patients with blunt thoracic trauma, and there is<br />

a lack of comparative data. 16 Paravertebral administration of local anesthetics<br />

likely has efficacy, and low complication rates, for multiple RFs, but<br />

the technique is outside most ED providers’ practice scope. 25–27

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