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Selected opioids
Maintenance
pediatric dose
Maintenance adult
dose c
Initial pediatric
dose
Initial adult
dose b
Route a
Medication Example
tradename
Pure agonists
15–60 mg q4–6 h 0.5–1 mg/kg q 4–6 h
PO 30 mg 0.5–1 mg/kg for
age >1 yr
Codeine Tylenol d
Fentanyl Sublimaze IV 50–100 μg 1–2 μg/kg 50–100 μg q1–2 h 0.5–2 μg/kg q1–4 h
IN 1–2 μg/kg 1–2 μg/kg 1–2 μg/kg q1–2 h
Nebulized 1–3 μg/kg 1–3 μg/kg 1–3 μg/kg q1–2 h 1–3 μg/kg q1–2 h
>30 min interval
between doses
Actiq Lozenge 200 μg 10–15 μg/kg >30 min interval
between doses
100 μg > 4 h interval
between doses
Fentora Buccal
tablet
5–10 mg q4–6 h 2.5 mg q4–6 h
PO 5–10 mg 2.5 mg for age
>6yr
Hydrocodone Vicodin d
2–8 mg q3–4 h 0.03–0.08 mg/kg
q4–6 h
Hydromorphone Dilaudid PO 1–2 mg 0.03 mg/kg for
age >6 mth
1–4 mg q 4–6 h 0.015 mg/kg q4–6 h
IV 1 mg 0.015 mg/kg for
age >6 mth
Demerol IV 50 mg 1.1–1.8 mg/kg 50–150 mg q3–4 h 1.1–1.8 mg/kg
q3–4 h
Meperidine
(pethidine)
10–30 mg q3–4 h 0.2–0.5 mg/kg
q4–6 h
Morphine MSContin PO 10–30 mg 0.2–0.5 mg/kg for
age >6 mth
15 mL 2:1000
solution q2–4 h
Oral rinse 15 mL 2:1000
solution