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xxii<br />

Abbreviations<br />

BID twice daily<br />

CNS central nervous system<br />

COX cyclooxygenase<br />

ED emergency department<br />

EM emergency medicine<br />

EMS emergency medical services<br />

FDA US Food and Drug Administration<br />

GI gastrointestinal<br />

HIV human immunodeficiency virus<br />

HS at bedtime<br />

ICP intracranial pressure<br />

IM intramuscular<br />

IN intranasal<br />

IU international units<br />

IV intravenous<br />

n number of patients or study subjects<br />

NSAID nonsteroidal anti-inflammatory drug<br />

OTM oral transmucosal<br />

PCA patient-controlled analgesia<br />

PO oral<br />

PR rectal<br />

q every (e.g. q8 h = every 8h)<br />

QD (once) daily<br />

QID four times daily<br />

RCT randomized, controlled trial<br />

SC subcutaneous<br />

SL sublingual<br />

SSRI selective serotonin reuptake inhibitor<br />

TD transdermal<br />

TID three times daily<br />

VAS visual analog scale

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