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Special cases:<br />

n antivenom available: consider for intractable pain or severe toxicity<br />

n Irukandji-like syndrome: magnesium (0.05 g/kg IV, maximum 2.5 g over<br />

20–30 min, with repeat dosing and infusion rates guided by side effects and<br />

magnesium levels); benzodiazepines (e.g. diazepam 5–10 mg IV q3–4h)<br />

for cramping<br />

n failure of acetic acid, especially for stings of the sea nettle: slurry of bicarbonate<br />

(baking soda) in water<br />

References<br />

Bites and stings – marine 121<br />

1. Watters MR, Stommel EW. Marine neurotoxins: envenomations and contact<br />

toxins. Curr Treat Options Neurol. 2004;6(2):115–123.<br />

2. Perkins RA, Morgan SS. Poisoning, envenomation, and trauma from marine<br />

creatures. Am Fam Physician. 15 2004;69(4):885–890.<br />

3. Atkinson PR, Boyle A, Hartin D, et al. Is hot water immersion an effective<br />

treatment for marine envenomation? Emerg Med J. 2006;23(7):503–508.<br />

4. Yoshimoto CM, Yanagihara AA. Cnidarian (coelenterate) envenomations in<br />

Hawai’i improve following heat application. Trans R Soc Trop Med Hyg.<br />

2002;96(3):300–303.<br />

5. Nomura JT, Sato RL, Ahern RM, et al. A randomized paired comparison trial of<br />

cutaneous treatments for acute jellyfish (Carybdea alata) stings. Am J Emerg<br />

Med. 2002;20(7):624–626.<br />

6. Clark RF, Girard RH, Rao D, et al. Stingray envenomation: a retrospective<br />

review of clinical presentation and treatment in 119 cases. J Emerg Med.<br />

2007;33(1):33–37.<br />

7. Kimball AB, Arambula KZ, Stauffer AR, et al. Efficacy of a jellyfish sting<br />

inhibitor in preventing jellyfish stings in normal volunteers. Wilderness<br />

Environ Med. 2004;15(2):102–108.<br />

8. Currie BJ. Marine antivenoms. J Toxicol Clin Toxicol. 2003;41(3):301–308.<br />

9. Fenner PJ, Williamson JA, Blenkin JA. Successful use of Chironex antivenom<br />

by members of the Queensland Ambulance Transport Brigade. Med J Aust.<br />

1989;151(11–12):708–710.<br />

10. Williamson JA, Le Ray LE, Wohlfahrt M, et al. Acute management of serious<br />

envenomation by box-jellyfish (Chironex fleckeri). Med J Aust. 1984;141(12–<br />

13):851–853.

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