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Neck and back pain – mechanical strain<br />

MICHAEL TURTURRO<br />

n Agents<br />

n NSAIDs<br />

n Opioids<br />

n Skeletal muscle relaxants<br />

n Benzodiazepines<br />

n Corticosteroids<br />

n Local anesthetics<br />

n Evidence<br />

Because of different therapeutic approaches, this text separates mechanical<br />

strain spinal pain (MSSP) from neck and back pain of other etiologies<br />

(e.g. spondylosis, radiculopathy). There may be some overlap in presentation,<br />

so referral to other chapters of this text addressing neck and back pain<br />

may be useful.<br />

The NSAIDs are the mainstay of therapy for nonradiating mechanical<br />

back pain, and also – by extrapolation of evidence from back pain<br />

studies – for neck strain. 1–4 Cochrane review of the relevant evidence<br />

(from over 50 trials) addressing MSSP pain relief concluded that NSAIDs<br />

are probably more effective than placebo; there is conflicting evidence<br />

as to whether NSAIDs are consistently better than other MSSP treatment<br />

alternatives. 4<br />

There are good data supporting a contention that there are no differences<br />

in the analgesic efficacies of the different NSAIDs for MSSP. 4 In most cases,<br />

because of its wide availability and low cost, ibuprofen (600 mg PO QID or<br />

800 mg PO TID) is a reasonable first-line therapy.<br />

Opioids are the preferred treatment for MSSP in patients who have not<br />

responded to, or who cannot take, NSAIDs. Although RCTs have not specifically<br />

evaluated opioid therapy for MSSP, support for their use can be<br />

263

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