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Special cases:<br />

n patients requiring on-demand relief for occasional GERD pain: pantoprazole<br />

20 mg PO QD<br />

n patients on chronic therapy (e.g. a PPI) with intermittent need for breakthrough<br />

pain relief: antacids (e.g. aluminum/magnesium salts, 2–4 teaspoons<br />

or 2–4 tablets PO, between meals and HS)<br />

n breastfeeding patients requiring systemic therapy: ranitidine 150 mg PO BID<br />

References<br />

Gastroesophageal reflux disease 229<br />

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9. Pandak WM, Arezo S, Everett S, et al. Short course of omeprazole: a better first<br />

diagnostic approach to noncardiac chest pain than endoscopy, manometry, or<br />

24-hour esophageal pH monitoring. J Clin Gastroenterol. 2002;35(4):307–314.<br />

10. Cremonini F, Wise J, Moayyedi P, et al. Diagnostic and therapeutic use of<br />

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