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54 Chronic pain<br />

care providers, it may be reasonable to refuse medications such as opioids<br />

until a stable doctor–patient relationship is established. One of the most<br />

important tools for long-term pain care provision is the “pain contract.”<br />

Acute care providers should seek to determine whether such a contract has<br />

been arranged for the patient presenting to the ED, and the terms of these<br />

contracts should be respected. In the rare instances when “out-of-contract”<br />

analgesia will be provided by the ED physician, contact with the longitudinal<br />

care provider is critical. In the occasionally inevitable instances for which<br />

the ED becomes the patient’s de facto primary care clinic, the acute care<br />

provider may need to develop (and document for future providers’ reference)<br />

a pain contract (see below).<br />

n Analgesic selections in chronic pain<br />

Patients with chronic pain conditions tend to take analgesics for far longer<br />

than the few days or weeks that suffice for acute pain. Consequently, the<br />

prescribing clinician must be particularly cognizant of the risks of side effects<br />

associated with longer-term use of the medications. Consideration of the<br />

risks may impact medication selection (as risk-to-benefit calculations are<br />

weighed). Alternatively, side effects may prompt the addition of adjunctive<br />

drugs (e.g. stool softeners, anti-dyspeptics) to improve tolerance of pain<br />

relievers.<br />

The fact that an agent or class is used frequently for a given condition<br />

should not lead to an assumption of efficacy. For instance, meta-analysis of<br />

opioid use for chronic low-back pain reveals that this oft-prescribed<br />

approach has only marginal efficacy and incurs a significant risk of<br />

addiction. 2 Similarly, despite their frequent prescription for neuropathic<br />

syndromes, NSAIDs – which are associated with well-described adverse<br />

effects – are generally unhelpful for neuropathy. Even for low-back pain, a<br />

condition in which there is some role for NSAID use in acute care, the chronic<br />

use of these analgesics may have unfavorable risk-to-benefit ratio. Besides<br />

well-publicized ulcer, renal, and cardiovascular risk (see the Arthritis chapter,<br />

p. 94), long-term NSAID use risks abdominal pain, diarrhea, edema, dry<br />

mouth, rash, dizziness, headache, and tiredness. 3 In the past, some experts

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